Structural Molecular Biology

BL14-1

Beam line 14-1 employs a vertically collimating Rh-coated Si mirror, and a double-crystal Si(111) monochromator with a 0.013% energy bandpass producing ~2x1011 p/s at 10 KeV and providing an energy range that extends from 6 to 13 KeV. A vertically and horizontally focusing toroid mirror produces a beam focus of 50 x 80 um2

BL12-2

BL12-2 is optimized for high-throughput micro-crystal macromolecular crystallography data collection to high-resolution.  BL12-2 also supports advanced serial and time-resolved crystallography methods.  BL12-2 is an undulator beam line with a fully adjustable focus. Micron-sized beams (10 x 10 µm2 or 20 x 20 µm2) are achieved with precision micro-collimators. BL12-2 is SAD and MAD capable and can be run in a fully remote access mode. 

BL12-1

BL12-1 is designed for investigations of the most challenging macromolecular crystallography systems confronting scientists today, including cases where crystals can only be grown to a few microns in size, serial room temperature studies and time-resolved measurements. BL12-1 supports fully remote-access experiments using samples at cryogenic conditions in uni-pucks or cassettes, and samples at controlled humidity and elevated-temperature conditions using specialized SSRL plates. 

BL9-3

Beam line 9-3 is a high flux focused wiggler side-station optimized for x-ray absorption spectroscopy (XANES and EXAFS) in the 5.5–30 keV range, for x-ray absorption spectroscopy and EXAFS measurements primarily on dilute biological systems. A dedicated LHe cryostat allows for routine low temperature measurements. The station features an LN2-cooled double-crystal Si(220) monochromator with energy resolution up to 10-4 (ΔE/E) and small vertical entrance slits to reduce intensity glitches.

BL9-2

BL 9-2 is a broad-fan wiggler end station dedicated for monochromatic, high-throughput and high-resolution macromolecular crystallography experiments. Optimized for SAD and MAD experiments, BL9-2 can be run in a full remote access mode and features a remote access-controlled UV-Vis microspectrophotometer for in-situ single crystal absorption spectroscopy measurements. 

BL7-3

Beam line 7-3 is a high flux wiggler side-station optimized for x-ray absorption spectroscopy (XANES and EXAFS) in the 5.5–40 keV range, dedicated for x-ray absorption spectroscopy and EXAFS measurements on dilute biological systems. A dedicated LHe cryostat allows for routine low temperature measurements. The unfocused beam on BL7-3 is ideal for samples especially susceptible to radiation damage, such as high-valent intermediates and other oxidized species.

BL7-1

Not supported for general users

Beam line 7-1 is a 8-pole, 2.0-Tesla wiggler side-station beam line optimized for monochromatic, high-throughput, high-resolution macromolecular crystallography. It is SAD and MAD capable and can be run in a full remote access mode. It is equipped with an ADSC Q315R CCD detector. Currenlty 7-1 is dedicated to staff development and user training.

See the Macromolecular Crystallography website for details.

BL4-1

Beam line 4-1 is a high-flux wiggler station optimized for x-ray absorption spectroscopy (XANES and EXAFS) in the 5–38 keV range, covering transition metals, lanthanides, actinides and P-block elements. BL4-1 accommodates radioactive materials (RAM) samples with radionuclides based on radiotoxicity level, activity, shielding requirements and experimental needs. The station features an LN2-cooled double-crystal Si(220) monochromator with energy resolution up to 10-5(ΔE/E) and small vertical entrance slits to reduce intensity glitches.

BL4-2

Beam line 4-2 is a small-angle scattering/diffraction station dedicated to structural biology studies primarily on non-crystalline systems. The instrument features a standard pin-hole geometry SAXS camera with an adjustable sample-to-detector distance from 0.25 m to 3.5 m in discreet steps. This allows optimizing the instrument according to experimental needs. A Pilatus3 X 1M is the primary detector, featuring a large active area, photon counting x-ray detection and a 500-Hz maximum frame rate which also enables fast time-resolved studies.