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Science

User Publications 2017

  1. Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy.
    Blocquel, D.; Li, S.; Wei, N.; Daub, H.; Sajish, M.; Erfurth, M.L.; Kooi, G.; Zhou, J.; Bai, G.; Schimmel, P.; Jordanova, A.; Yang, X.L. Nucleic Acids Res 45, 8091-8104 (2017).
  2. Controllable Activation of Nanoscale Dynamics in a Disordered Protein Alters Binding Kinetics.
    Callaway, D.J.E.; Matsui, T.; Weiss, T.; Stingaciu, L.R.; Stanley, C.B.; Heller, W.T.; Bu, Z. J Mol Biol 429, 987-998 (2017).
  3. Phospho-Priming Confers Functionally Relevant Specificities for Rad53 Kinase Autophosphorylation.
    Chen, E.ShengWen; Weng, J.H.; Chen, Y.H.; Wang, S.C.; Liu, X.X.; Huang, W.C.; Matsui, T.; Kawano, Y.; Liao, J.H.; Lim, L.H.; Bessho, Y.; Huang, K.F.; Wu, W.J.; Tsai, M.D. Biochemistry 56, 5112-5124 (2017).
  4. Paclitaxel suppresses Tau-mediated microtubule bundling in a concentration-dependent manner.
    Choi, M.Chul; Chung, P.J.; Song, C.; Miller, H.P.; Kiris, E.; Li, Y.; Wilson, L.; Feinstein, S.C.; Safinya, C.R. Biochim Biophys Acta 1861, 3456-3463 (2017).
  5. Synchrotron small-angle X-ray scattering and electron microscopy characterization of structures and forces in microtubule/Tau mixtures.
    Chung, P.J.; Song, C.; Miller, H.P.; Li, Y.; Raviv, U.; Choi, M.Chul; Wilson, L.; Feinstein, S.C.; Safinya, C.R. Methods Cell Biol 141, 155-178 (2017).
  6. Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization.
    de la Peña, A.Torrents; Julien, J.P.; de Taeye, S.W.; Garces, F.; Guttman, M.; Ozorowski, G.; Pritchard, L.K.; Behrens, A.J.; Go, E.P.; Burger, J.A.; Schermer, E.E.; Sliepen, K.; Ketas, T.J.; Pugach, P.; Yasmeen, A.; Cottrell, C.A.; Torres, J.L.; Vavourakis, C.D.; van Gils, M.J.; LaBranche, C.; Montefiori, D.C.; Desaire, H.; Crispin, M.; Klasse, P.Johan; Lee, K.K.; Moore, J.P.; Ward, A.B.; Wilson, I.A.; Sanders, R.W. Cell Rep 20, 1805-1817 (2017).
  7. Internal Structure and Preferential Protein Binding of Colloidal Aggregates.
    Duan, D.; Torosyan, H.; Elnatan, D.; McLaughlin, C.K.; Logie, J.; Shoichet, M.S.; Agard, D.A.; Shoichet, B.K. ACS Chem Biol 12, 282-290 (2017).
  8. Environmental Calcium Controls Alternate Physical States of the Caulobacter Surface Layer.
    Herrmann, J.; Jabbarpour, F.; Bargar, P.G.; Nomellini, J.F.; Li, P.N.; Lane, T.J.; Weiss, T.M.; Smit, J.; Shapiro, L.; Wakatsuki, S. Biophys J 112, 1841-1851 (2017).
  9. Hydrophilic Phage-Mimicking Membrane Active Antimicrobials Reveal Nanostructure-Dependent Activity and Selectivity.
    Jiang, Y.; Zheng, W.; Kuang, L.; Ma, H.; Liang, H. ACS Infect Dis 3, 676-687 (2017).
  10. Structural and functional characterization of α-catenin reveals constitutive binding to β-catenin and F-actin.
    Kang, H.; Bang, I.; Jin, K.Sik; Lee, B.; Lee, J.; Shao, X.; Heier, J.A.; Kwiatkowski, A.V.; Nelson, J.; Hardin, J.; Weis, W.I.; Choi, H.J. J Biol Chem 292, 7077-7086 (2017).
  11. Direct Antimicrobial Activity of IFN-β.
    Kaplan, A.; Lee, M.W.; Wolf, A.J.; Limon, J.J.; Becker, C.A.; Ding, M.; Murali, R.; Lee, E.Y.; Liu, G.Y.; Wong, G.C.L.; Underhill, D.M. J Immunol 198, 4036-4045 (2017).
  12. Crystallinity of Double-Stranded RNA-Antimicrobial Peptide Complexes Modulates Toll-Like Receptor 3-Mediated Inflammation.
    Lee, E.Y.; Takahashi, T.; Curk, T.; Dobnikar, J.; Gallo, R.L.; Wong, G.C.L. ACS Nano 11, 12145-12155 (2017).
  13. What can machine learning do for antimicrobial peptides, and what can antimicrobial peptides do for machine learning?
    Lee, E.Y.; Lee, M.W.; Fulan, B.M.; Ferguson, A.L.; Wong, G.C.L. Interface Focus 7, 20160153 (2017).
  14. Structural features of NS3 of Dengue virus serotypes 2 and 4 in solution and insight into RNA binding and the inhibitory role of quercetin.
    Pan, A.; Saw, W.Geok; Manimekalai, M.Sony Subra; Grüber, A.; Joon, S.; Matsui, T.; Weiss, T.M.; Grüber, G. Acta Crystallogr D Struct Biol 73, 402-419 (2017).
  15. Plasmon-actuated nano-assembled microshells.
    Quint, M.T.; Sarang, S.; Quint, D.A.; Keshavarz, A.; Stokes, B.J.; Subramaniam, A.Bala; Huang, K.Casey; Gopinathan, A.; Hirst, L.S.; Ghosh, S. Sci Rep 7, 17788 (2017).
  16. Determination of the conformational ensemble of the TAR RNA by X-ray scattering interferometry.
    Shi, X.; Walker, P.; Harbury, P.B.; Herschlag, D. Nucleic Acids Res 45, e64 (2017).
  17. Distinct solubility and cytotoxicity regimes of paclitaxel-loaded cationic liposomes at low and high drug content revealed by kinetic phase behavior and cancer cell viability studies.
    Steffes, V.M.; Murali, M.M.; Park, Y.; Fletcher, B.J.; Ewert, K.K.; Safinya, C.R. Biomaterials 145, 242-255 (2017).
  18. Bacterial amyloid curli acts as a carrier for DNA to elicit an autoimmune response via TLR2 and TLR9.
    Tursi, S.A.; Lee, E.Y.; Medeiros, N.J.; Lee, M.H.; Nicastro, L.K.; Buttaro, B.; Gallucci, S.; Wilson, R.Paul; Wong, G.C.L.; Tükel, Ç. PLoS Pathog 13, e1006315 (2017).
  19. Molecular Architecture of the Major Membrane Ring Component of the Nuclear Pore Complex.
    Upla, P.; Kim, S.Joong; Sampathkumar, P.; Dutta, K.; Cahill, S.M.; Chemmama, I.E.; Williams, R.; Bonanno, J.B.; Rice, W.J.; Stokes, D.L.; Cowburn, D.; Almo, S.C.; Sali, A.; Rout, M.P.; Fernandez-Martinez, J. Structure 25, 434-445 (2017).
  20. The molecular architecture of the yeast spindle pole body core determined by Bayesian integrative modeling.
    Viswanath, S.; Bonomi, M.; Kim, S.Joong; Klenchin, V.A.; Taylor, K.C.; Yabut, K.C.; Umbreit, N.T.; Van Epps, H.A.; Meehl, J.; Jones, M.H.; Russel, D.; Velazquez-Muriel, J.A.; Winey, M.; Rayment, I.; Davis, T.N.; Sali, A.; Muller, E.G. Mol Biol Cell 28, 3298-3314 (2017).
  21. Dynamic intramolecular regulation of the histone chaperone nucleoplasmin controls histone binding and release.
    Warren, C.; Matsui, T.; Karp, J.M.; Onikubo, T.; Cahill, S.; Brenowitz, M.; Cowburn, D.; Girvin, M.; Shechter, D. Nat Commun 8, 2215 (2017).