User Publications (2013 - 2022)
You are here
-
Adaptable SEC-SAXS data collection for higher quality structure analysis in solution.
Matsui, T.; Rajkovic, I.; Mooers, B.H.M.; Liu, P.; Weiss, T.M. Protein Science 33, (2024).
-
Revealing Temperature-dependent Polymer Aggregation in Solution with Small-angle X-ray Scattering
Abdelsamie, M.; Chaney, T.P.; Yan, H.; Schneider, S.A.; Ayhan, I.A.; Gomez, E.D.; Reynolds, J.R.; Toney, M.F. J. Mater. Chem. A 10, (2022).
-
Viscoelastic analysis of mussel threads reveals energy dissipative mechanisms.
Areyano, M.; Valois, E.; Carvajal, I.Sanchez; Rajkovic, I.; Wonderly, W.R.; Kossa, A.; McMeeking, R.M.; Waite, H. J R Soc Interface 19, 20210828 (2022).
-
Design of a Flexible, Zn-Selective Protein Scaffold that Displays Anti-Irving-Williams Behavior.
Choi, T.Su; Tezcan, A. J Am Chem Soc 144, 18090-18100 (2022).
-
Overcoming universal restrictions on metal selectivity by protein design.
Choi, T.Su; Tezcan, A. Nature 603, 522-527 (2022).
-
Stabilization of glucose-6-phosphate dehydrogenase oligomers enhances catalytic activity and stability of clinical variants.
Garcia, A.Ann; Mathews, I.I.; Horikoshi, N.; Matsui, T.; Kaur, M.; Wakatsuki, S.; Mochly-Rosen, D. J Biol Chem 298, 101610 (2022).
-
Formation Mechanism of Flower-like Polyacrylonitrile Particles
Gong, H.; Ilavsky, J.; Kuzmenko, I.; Chen, S.; Yan, H.; Cooper, C.B.; Chen, G.; Chen, Y.; Chiong, J.A.; Jiang, Y.; Lai, J.C.; Zheng, Y.; Stone, K.H.; Huelsenbeck, L.; Giri, G.; Tok, J.B.H.; Bao, Z. J. Am. Chem. Soc. 144, (2022).
-
Dynamic, Polymer-Integrated Crystals for Efficient, Reversible Protein Encapsulation.
Han, K.; Na, Y.; Zhang, L.; Tezcan, A. J Am Chem Soc 144, 10139-10144 (2022).
-
Hydrophilic nanoparticles that kill bacteria while sparing mammalian cells reveal the antibiotic role of nanostructures.
Jiang, Y.; Zheng, W.; Tran, K.; Kamilar, E.; Bariwal, J.; Ma, H.; Liang, H. Nat Commun 13, 197 (2022).
-
Assembly of ordered DNA-curli fibril complexes during Salmonella biofilm formation correlates with strengths of the type I interferon and autoimmune responses.
Nicastro, L.K.; de Anda, J.; Jain, N.; Grando, K.C.M.; Miller, A.L.; Bessho, S.; Gallucci, S.; Wong, G.C.L.; Tükel, Ç. PLoS Pathog 18, e1010742 (2022).
-
Conjugated Polyelectrolyte-based Ternary Exciton Funnels via Liposome Scaffolds
Palmer, J.; Segura, C.J.; Matsushima, L.; Abrams, B.; Lee, H.W.; Ayzner, A.L. Mol. Syst. Des. Eng. 7, (2022).
-
The Influence of Calcium Ions (Ca2+) on the Enzymatic Hydrolysis of Lipopolysaccharide Aggregates to Liberate Free Fatty Acids (FFA) in Aqueous Solution
Pazol, J.; Weiss, T.M.; Martínez, C.D.; Quesada, O.; Nicolau, E. Jcis Open 7, (2022).
-
Energy Transfer in Aqueous Light Harvesting Antennae Based on Brush-like Inter-Conjugated Polyelectrolyte Complexes.
Pitch, G.M.; Matsushima, L.N.; Kraemer, Y.; Dailing, E.A.; Ayzner, A.L. Macromolecules 55, 10302-10311 (2022).
-
From Protein Design to the Energy Landscape of a Cold Unfolding Protein.
Pulavarti, S.V.S.R.K.; Maguire, J.B.; Yuen, S.; Harrison, J.S.; Griffin, J.; Premkumar, L.; Esposito, E.A.; Makhatadze, G.I.; Garcia, A.E.; Weiss, T.M.; Snell, E.H.; Kuhlman, B.; Szyperski, T. J Phys Chem B 126, 1212-1231 (2022).
-
A round-robin approach provides a detailed assessment of biomolecular small-angle scattering data reproducibility and yields consensus curves for benchmarking.
Trewhella, J.; Vachette, P.; Bierma, J.; Blanchet, C.; Brookes, E.; Chakravarthy, S.; Chatzimagas, L.; Cleveland, T.E.; Cowieson, N.; Crossett, B.; Duff, A.P.; Franke, D.; Gabel, F.; Gillilan, R.E.; Graewert, M.; Grishaev, A.; Guss, M.; Hammel, M.; Hopkins, J.; Huang, Q.; Hub, J.S.; Hura, G.L.; Irving, T.C.; Jeffries, C.Michael; Jeong, C.; Kirby, N.; Krueger, S.; Martel, A.; Matsui, T.; Li, N.; Pérez, J.; Porcar, L.; Prangé, T.; Rajkovic, I.; Rocco, M.; Rosenberg, D.J.; Ryan, T.M.; Seifert, S.; Sekiguchi, H.; Svergun, D.; Teixeira, S.; Thureau, A.; Weiss, T.M.; Whitten, A.E.; Wood, K.; Zuo, X. Acta Crystallogr D Struct Biol 78, 1315-1336 (2022).
-
Histidine-Mediated Ion Specific Effects Enable Salt Tolerance of a Pore-Forming Marine Antimicrobial Peptide.
Xian, W.; Hennefarth, M.R.; Lee, M.W.; Do, T.; Lee, E.Y.; Alexandrova, A.N.; Wong, G.C.L. Angew Chem Int Ed Engl 61, e202108501 (2022).
-
Mechanism of Additive-Assisted Room-Temperature Processing of Metal Halide Perovskite Thin Films.
Abdelsamie, M.; Li, T.; Babbe, F.; Xu, J.; Han, Q.; Blum, V.; Sutter-Fella, C.M.; Mitzi, D.B.; Toney, M.F. ACS Appl Mater Interfaces 13, 13212-13225 (2021).
-
Structural basis for ALK2/BMPR2 receptor complex signaling through kinase domain oligomerization.
Agnew, C.; Ayaz, P.; Kashima, R.; Loving, H.S.; Ghatpande, P.; Kung, J.E.; Underbakke, E.S.; Shan, Y.; Shaw, D.E.; Hata, A.; Jura, N. Nat Commun 12, 4950 (2021).
-
X-ray Fiber Diffraction and Computational Analyses of Stacked Hexads in Supramolecular Polymers: Insight into Self-Assembly in Water by Prospective Prebiotic Nucleobases.
Alenaizan, A.; Borca, C.H.; Karunakaran, S.C.; Kendall, A.K.; Stubbs, G.; Schuster, G.B.; Sherrill, D.; Hud, N.V. J Am Chem Soc 143, 6079-6094 (2021).
-
Covalent inhibition of hAChE by organophosphates causes homodimer dissociation through long-range allosteric effects.
Blumenthal, D.K.; Cheng, X.; Fajer, M.; Ho, K.Y.; Rohrer, J.; Gerlits, O.; Taylor, P.; Juneja, P.; Kovalevsky, A.; Radić, Z. J Biol Chem 297, 101007 (2021).
-
High Energy Density Shape Memory Polymers Using Strain-Induced Supramolecular Nanostructures.
Cooper, C.B.; Nikzad, S.; Yan, H.; Ochiai, Y.; Lai, J.C.; Yu, Z.; Chen, G.; Kang, J.; Bao, Z. ACS Cent Sci 7, 1657-1667 (2021).
-
Acetaminophen Interactions with Phospholipid Vesicles Induced Changes in Morphology and Lipid Dynamics.
De Mel, J.U.; Gupta, S.; Harmon, S.; Stingaciu, L.; Roth, E.W.; Siebenbuerger, M.; Bleuel, M.; Schneider, G.J. Langmuir 37, 9560-9570 (2021).
-
Manipulating Phospholipid Vesicles at the Nanoscale: A Transformation from Unilamellar to Multilamellar by an -Alkyl-poly(ethylene oxide).
De Mel, J.U.; Gupta, S.; Willner, L.; Allgaier, J.; Stingaciu, L.R.; Bleuel, M.; Schneider, G.J. Langmuir 37, 2362-2375 (2021).
-
Nanostructure-specific X-ray tomography reveals myelin levels, integrity and axon orientations in mouse and human nervous tissue.
Georgiadis, M.; Schroeter, A.; Gao, Z.; Guizar-Sicairos, M.; Liebi, M.; Leuze, C.; McNab, J.A.; Balolia, A.; Veraart, J.; Ades-Aron, B.; Kim, S.; Shepherd, T.; Lee, C.H.; Walczak, P.; Chodankar, S.; DiGiacomo, P.; David, G.; Augath, M.; Zerbi, V.; Sommer, S.; Rajkovic, I.; Weiss, T.; Bunk, O.; Yang, L.; Zhang, J.; Novikov, D.S.; Zeineh, M.; Fieremans, E.; Rudin, M. Nat Commun 12, 2941 (2021).
-
PlzA is a bifunctional c-di-GMP biosensor that promotes tick and mammalian host-adaptation of Borrelia burgdorferi.
Groshong, A.M.; Grassmann, A.A.; Luthra, A.; McLain, M.A.; Provatas, A.A.; Radolf, J.D.; Caimano, M.J. PLoS Pathog 17, e1009725 (2021).
-
Early-Stage Aggregation and Crystalline Interactions of Peptoid Nanomembranes.
Hammons, J.A.; Baer, M.D.; Jian, T.; Lee, J.R.I.; Weiss, T.M.; De Yoreo, J.J.; Noy, A.; Chen, C.L.; Van Buuren, A. J Phys Chem Lett 12, 6126-6133 (2021).
-
Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency.
Horikoshi, N.; Hwang, S.; Gati, C.; Matsui, T.; Castillo-Orellana, C.; Raub, A.G.; Garcia, A.A.; Jabbarpour, F.; Batyuk, A.; Broweleit, J.; Xiang, X.; Chiang, A.; Broweleit, R.; Vöhringer-Martinez, E.; Mochly-Rosen, D.; Wakatsuki, S. Proc Natl Acad Sci U S A 118, (2021).
-
Dynamics and stability in the maturation of a eukaryotic virus: a paradigm for chemically programmed large-scale macromolecular reorganization.
Johnson, J.E.; Domitrovic, T.; Matsui, T.; Castells-Graells, R.; Lomonossoff, G. Arch Virol 166, 1547-1563 (2021).
-
Sequence determinants in the cathelicidin LL-37 that promote inflammation via presentation of RNA to scavenger receptors.
Kulkarni, N.N.; O'Neill, A.M.; Dokoshi, T.; Luo, E.W.C.; Wong, G.C.L.; Gallo, R.L. J Biol Chem 297, 100828 (2021).
-
PACAP is a pathogen-inducible resident antimicrobial neuropeptide affording rapid and contextual molecular host defense of the brain.
Lee, E.Y.; Chan, L.C.; Wang, H.; Lieng, J.; Hung, M.; Srinivasan, Y.; Wang, J.; Waschek, J.A.; Ferguson, A.L.; Lee, K.F.; Yount, N.Y.; Yeaman, M.R.; Wong, G.C.L. Proc Natl Acad Sci U S A 118, (2021).
-
Apolipoprotein Mimetic Peptide Inhibits Neutrophil-Driven Inflammatory Damage via Membrane Remodeling and Suppression of Cell Lysis.
Lee, M.W.; Luo, E.WeiChia; Silvestre-Roig, C.; Srinivasan, Y.; Akabori, K.; Lemnitzer, P.; Schmidt, N.W.; Lai, G.Hwee; Santangelo, C.D.; Soehnlein, O.; Wong, G.C.L. ACS Nano 15, 15930-15939 (2021).
-
SAXS structure of homodimeric oxyHemoglobin III from bivalve Lucina pectinata.
Marchany-Rivera, D.; Estremera-Andújar, R.A.; Nieves-Marrero, C.; Ruiz-Martínez, C.R.; Bauer, W.; López-Garriga, J. Biopolymers 112, e23427 (2021).
-
Advances in the Structural Design of Polyelectrolyte Complex Micelles.
Marras, A.E.; Ting, J.M.; Stevens, K.C.; Tirrell, M.V. J Phys Chem B 125, 7076-7089 (2021).
-
Architecturally complex -glycopeptidases are customized for mucin recognition and hydrolysis.
Pluvinage, B.; Ficko-Blean, E.; Noach, I.; Stuart, C.; Thompson, N.; McClure, H.; Buenbrazo, N.; Wakarchuk, W.; Boraston, A.B. Proc Natl Acad Sci U S A 118, (2021).
-
Design of metal-mediated protein assemblies via hydroxamic acid functionalities.
Subramanian, R.H.; Zhu, J.; Bailey, J.B.; Chiong, J.A.; Li, Y.; Golub, E.; Tezcan, A. Nat Protoc 16, 3264-3297 (2021).
-
CMT2N-causing aminoacylation domain mutants enable Nrp1 interaction with AlaRS.
Sun, L.; Wei, N.; Kuhle, B.; Blocquel, D.; Novick, S.; Matuszek, Z.; Zhou, H.; He, W.; Zhang, J.; Weber, T.; Horvath, R.; Latour, P.; Pan, T.; Schimmel, P.; Griffin, P.R.; Yang, X.L. Natl. Acad. Sci. USA 118, (2021).
-
Highly Basic Clusters in the Herpes Simplex Virus 1 Nuclear Egress Complex Drive Membrane Budding by Inducing Lipid Ordering.
Thorsen, M.K.; Lai, A.; Lee, M.W.; Hoogerheide, D.P.; Wong, G.C.L.; Freed, J.H.; Heldwein, E.E. mBio 12, 01548-21 (2021).
-
Paclitaxel loading in cationic liposome vectors is enhanced by replacement of oleoyl with linoleoyl tails with distinct lipid shapes.
Zhen, Y.; Ewert, K.K.; Fisher, W.S.; Steffes, V.M.; Li, Y.; Safinya, C.R. Sci Rep 11, 7311 (2021).
-
Lignin-Graft-Poly(lactic--glycolic) Acid Biopolymers for Polymeric Nanoparticle Synthesis.
Astete, C.E.; De Mel, J.U.; Gupta, S.; Noh, Y.R.; Bleuel, M.; Schneider, G.J.; Sabliov, C.M. ACS Omega 5, 9892-9902 (2020).
-
Enhanced purification coupled with biophysical analyses shows cross-β structure as a core building block for Streptococcus mutans functional amyloids.
Barran-Berdon, A.L.; Ocampo, S.; Haider, M.; Morales-Aparicio, J.; Ottenberg, G.; Kendall, A.; Yarmola, E.; Mishra, S.; Long, J.R.; Hagen, S.J.; Stubbs, G.; Brady, J. Sci Rep 10, 5138 (2020).
-
Higher order assembling of the mycobacterial polar growth factor DivIVA/Wag31.
Choukate, K.; Gupta, A.; Basu, B.; Virk, K.; Ganguli, M.; Chaudhuri, B. J Struct Biol 209, 107429 (2020).
-
The C-Terminal Domain of α-Synuclein Confers Steric Stabilization on Synaptic Vesicle-like Surfaces
Chung, P.J.; Hwang, H.Luke; Slaw, B.R.; Leong, A.; Adams, E.J.; Lee, K.Yee C. Adv. Mater. Interf. 7, (2020).
-
Antibody Probes of Module 1 of the 6-Deoxyerythronolide B Synthase Reveal an Extended Conformation During Ketoreduction.
Cogan, D.P.; Li, X.; Sevillano, N.; Mathews, I.I.; Matsui, T.; Craik, C.S.; Khosla, C. J Am Chem Soc 142, 14933-14939 (2020).
-
Multivalent Assembly of Flexible Polymer Chains into Supramolecular Nanofibers.
Cooper, C.B.; Kang, J.; Yin, Y.; Yu, Z.; Wu, H.C.; Nikzad, S.; Ochiai, Y.; Yan, H.; Cai, W.; Bao, Z. J Am Chem Soc 142, 16814-16824 (2020).
-
Switchable Membrane Remodeling and Antifungal Defense by Metamorphic Chemokine XCL1.
Dishman, A.F.; Lee, M.W.; de Anda, J.; Lee, E.Y.; He, J.; Huppler, A.R.; Wong, G.C.L.; Volkman, B.F. ACS Infect Dis 6, 1204-1213 (2020).
-
Engineering Supramolecular Polymer Conformation for Efficient Carbon Nanotube Sorting.
Gao, T.Z.; Sun, Z.; Yan, X.; Wu, H.C.; Yan, H.; Bao, Z. Small 16, e2000923 (2020).
-
The influence of proline isomerization on potency and stability of anti-HIV antibody 10E8.
Guttman, M.; Padte, N.N.; Huang, Y.; Yu, J.; Rocklin, G.J.; Weitzner, B.D.; Scian, M.; Ho, D.D.; Lee, K.K. Sci Rep 10, 14313 (2020).
-
Anisotropic Dynamics and Mechanics of Macromolecular Crystals Containing Lattice-Patterned Polymer Networks.
Han, K.; Bailey, J.B.; Zhang, L.; Tezcan, A. J Am Chem Soc 142, 19402-19410 (2020).
-
A bacterial surface layer protein exploits multistep crystallization for rapid self-assembly.
Herrmann, J.; Li, P.N.; Jabbarpour, F.; Chan, A.C.K.; Rajkovic, I.; Matsui, T.; Shapiro, L.; Smit, J.; Weiss, T.M.; Murphy, M.E.P.; Wakatsuki, S. Proc Natl Acad Sci U S A 117, 388-394 (2020).
-
Semiconducting Eggs and Ladders: Understanding Exciton Landscape Formation in Aqueous π-Conjugated Inter-Polyelectrolyte Complexes
Hollingsworth, W.R.; Williams, V.; Ayzner, A.L. Macromolecules 53, 2724-2734 (2020).
-
Halogenation-Dependent Effects of the Chlorosulfolipids of on Lipid Bilayers.
Iii, F.R.Moss; Cabrera, G.E.; McKenna, G.M.; Salerno, G.J.; Shuken, S.R.; Landry, M.L.; Weiss, T.M.; Burns, N.Z.; Boxer, S.G. ACS Chem Biol 15, 2986-2995 (2020).
-
How do cyclic antibiotics with activity against Gram-negative bacteria permeate membranes? A machine learning informed experimental study.
Lee, M.W.; de Anda, J.; Kroll, C.; Bieniossek, C.; Bradley, K.; Amrein, K.E.; Wong, G.C.L. Biochim Biophys Acta Biomembr 1862, 183302 (2020).
-
Structural insights of the enzymes from the chitin utilization locus of Flavobacterium johnsoniae.
Mazurkewich, S.; Helland, R.; Mackenzie, A.; Eijsink, V.G.H.; Pope, P.B.; Brändén, G.; Larsbrink, J. Sci Rep 10, 13775 (2020).
-
Assembly of Building Blocks by Double-End-Anchored Polymers in the Dilute Regime Mediated by Hydrophobic Interactions at Controlled Distances.
Wonder, E.A.; Ewert, K.K.; Liu, C.; Steffes, V.M.; Kwak, J.; Qahar, V.; Majzoub, R.N.; Zhang, Z.; Carragher, B.; Potter, C.S.; Li, Y.; Qiao, W.; Safinya, C.R. ACS Appl Mater Interfaces 12, 45728-45743 (2020).
-
Spatiotemporal Formation and Growth Kinetics of Polyelectrolyte Complex Micelles with Millisecond Resolution
Wu, H.; Ting, J.M.; Yu, B.; Jackson, N.E.; Meng, S.; de Pablo, J.J.; Tirrell, M.V. ACS Macro Lett. 9, 1674-1680 (2020).
-
The structural ensemble of a Holliday junction determined by X-ray scattering interference.
Zettl, T.; Shi, X.; Bonilla, S.; Sedlak, S.M.; Lipfert, J.; Herschlag, D. Nucleic Acids Res 48, 8090-8098 (2020).
-
Environmentally Benign Nanoantibiotics with a Built-in Deactivation Switch Responsive to Natural Habitats.
Zheng, W.; Anzaldua, M.; Arora, A.; Jiang, Y.; McIntyre, K.; Doerfert, M.; Winter, T.; Mishra, A.; Ma, H.; Liang, H. Biomacromolecules 21, 2187-2198 (2020).
-
CMT disease severity correlates with mutation-induced open conformation of histidyl-tRNA synthetase, not aminoacylation loss, in patient cells.
Blocquel, D.; Sun, L.; Matuszek, Z.; Li, S.; Weber, T.; Kuhle, B.; Kooi, G.; Wei, N.; Baets, J.; Pan, T.; Schimmel, P.; Yang, X.L. Proc Natl Acad Sci U S A 116, 19440-19448 (2019).
-
3D Columnar Phase of Stacked Short DNA Organized by Coherent Membrane Undulations.
Bouxsein, N.F.; Leal, C.; McAllister, C.S.; Li, Y.; Ewert, K.K.; Samuel, C.E.; Safinya, C.R. Langmuir 35, 11891-11901 (2019).
-
An ensemble of flexible conformations underlies mechanotransduction by the cadherin-catenin adhesion complex.
Bush, M.; Alhanshali, B.M.; Qian, S.; Stanley, C.B.; Heller, W.T.; Matsui, T.; Weiss, T.M.; Nicholl, I.D.; Walz, T.; Callaway, D.J.E.; Bu, Z. Proc Natl Acad Sci U S A 116, 21545-21555 (2019).
-
Structure of the full-length Clostridium difficile toxin B.
Chen, P.; Lam, K.H.; Liu, Z.; Mindlin, F.A.; Chen, B.; Gutierrez, C.B.; Huang, L.; Zhang, Y.; Hamza, T.; Feng, H.; Matsui, T.; Bowen, M.E.; Perry, K.; Jin, R. Nat Struct Mol Biol 26, 712-719 (2019).
-
α-Synuclein Sterically Stabilizes Spherical Nanoparticle-Supported Lipid Bilayers
Chung, P.J.; Zhang, Q.; Hwang, H.L.; Leong, A.; Maj, P.; Szczygiel, R.; Dufresne, E.M.; Narayanan, S.; Adams, E.J.; Lee, K.Y.C. ACS Appl Bio Mater 2, 1413-1419 (2019).
-
STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition.
Ergun, S.L.; Fernandez, D.; Weiss, T.M.; Li, L. Cell 178, 290-301.e10 (2019).
-
CXCL4 assembles DNA into liquid crystalline complexes to amplify TLR9-mediated interferon-α production in systemic sclerosis.
Lande, R.; Lee, E.Y.; Palazzo, R.; Marinari, B.; Pietraforte, I.; Santos, G.Santiago; Mattenberger, Y.; Spadaro, F.; Stefanantoni, K.; Iannace, N.; Dufour, A.Maria; Falchi, M.; Bianco, M.; Botti, E.; Bianchi, L.; Alvarez, M.; Riccieri, V.; Truchetet, M.E.; Wong, G.C.L.; Chizzolini, C.; Frasca, L. Nat Commun 10, 1731 (2019).
-
Helical antimicrobial peptides assemble into protofibril scaffolds that present ordered dsDNA to TLR9.
Lee, E.Y.; Zhang, C.; Di Domizio, J.; Jin, F.; Connell, W.; Hung, M.; Malkoff, N.; Veksler, V.; Gilliet, M.; Ren, P.; Wong, G.C.L. Nat Commun 10, 1012 (2019).
-
Conformational communication mediates the reset step in t6A biosynthesis.
Luthra, A.; Paranagama, N.; Swinehart, W.; Bayooz, S.; Phan, P.; Quach, V.; Schiffer, J.M.; Stec, B.; Iwata-Reuyl, D.; Swairjo, M.A. Nucleic Acids Res 47, 6551-6567 (2019).
-
Decoupling of mechanical properties and ionic conductivity in supramolecular lithium ion conductors
Mackanic, D.G.; Yan, X.; Zhang, Q.; Matsuhisa, N.; Yu, Z.; Jiang, Y.; Manika, T.; Lopez, J.; Yan, H.; Liu, K.; Chen, X.; Cui, Y.; Bao, Z. Nat Commun 10, 5384 (2019).
-
Importin-9 wraps around the H2A-H2B core to act as nuclear importer and histone chaperone.
Padavannil, A.; Sarkar, P.; Kim, S.Joong; Cagatay, T.; Jiou, J.; Brautigam, C.A.; Tomchick, D.R.; Sali, A.; D'Arcy, S.; Chook, Y.Min Elife 8, (2019).
-
Challenge and Solution of Characterizing Glass Transition Temperature for Conjugated Polymers by Differential Scanning Calorimetry
Qian, Z.; Galuska, L.; McNutt, W.W.; Ocheje, M.U.; He, Y.; Cao, Z.; Zhang, S.; Xu, J.; Hong, K.; Goodman, R.B.; Rondeau-Gagne, S.; Mei, J.; Gu, X. J. Polym. Sci. B 57, 1635 (2019).
-
Minireview - Microtubules and Tubulin Oligomers: Shape Transitions and Assembly by Intrinsically Disordered Protein Tau and Cationic Biomolecules.
Safinya, C.R.; Chung, P.J.; Song, C.; Li, Y.; Miller, H.P.; Choi, M.Chul; Raviv, U.; Ewert, K.K.; Wilson, L.; Feinstein, S.C. Langmuir , (2019).
-
Interaction of dequalinium chloride with phosphatidylcholine bilayers: A biophysical study with consequences on the development of lipid-based mitochondrial nanomedicines.
Sauvage, F.; Legrand, F.X.; Roux, M.; Rajkovic, I.; Weiss, T.M.; Varga, Z.; Augis, L.; Nugue, G.; Debouzy, J.C.; Vergnaud-Gauduchon, J.; Barratt, G. J Colloid Interface Sci 537, 704-715 (2019).
-
Influence of micelle charge density on adsorption and exciton delocalization of conjugated polyelectrolytes
Segura, C.J.; Johnston, A.R.; Hollingsworth, W.R.; Rajkovic, I.; Ayzner, A.L. Proc. SPIE 11084, Physical Chemistry of Semiconductor Materials and Interfaces XVIII , 110840A (2019).
-
Disassembly of an Interconjugated Polyelectrolyte Complex Using Ionic Surfactants
Segura, C.J.; Lucero, M.; Ayzner, A.L. ACS Appl Polym Mater 1, 1034-1044 (2019).
-
A Central Region of NF-κB Essential Modulator Is Required for IKKβ-Induced Conformational Change and for Signal Propagation.
Shaffer, R.; DeMaria, A.M.; Kagermazova, L.; Liu, Y.; Babaei, M.; Caban-Penix, S.; Cervantes, A.; Jehle, S.; Makowski, L.; Gilmore, T.D.; Whitty, A.; Allen, K.N. Biochemistry 58, 2906-2920 (2019).
-
Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death.
Silvestre-Roig, C.; Braster, Q.; Wichapong, K.; Lee, E.Y.; Teulon, J.Marie; Berrebeh, N.; Winter, J.; Adrover, J.M.; Santos, G.Santiago; Froese, A.; Lemnitzer, P.; Ortega-Gómez, A.; Chevre, R.; Marschner, J.; Schumski, A.; Winter, C.; Perez-Olivares, L.; Pan, C.; Paulin, N.; Schoufour, T.; Hartwig, H.; González-Ramos, S.; Kamp, F.; Megens, R.T.A.; Mowen, K.A.; Gunzer, M.; Maegdefessel, L.; Hackeng, T.; Lutgens, E.; Daemen, M.; von Blume, J.; Anders, H.J.; Nikolaev, V.O.; Pellequer, J.L.; Weber, C.; Hidalgo, A.; Nicolaes, G.A.F.; Wong, G.C.L.; Soehnlein, O. Nature 569, 236-240 (2019).
-
Binding partner- and force-promoted changes in αE-catenin conformation probed by native cysteine labeling
Terekhova, K.; Pokutta, S.; Kee, Y.S.; Li, J.; Tajkhorshid, E.; Fuller, G.; Dunn, A.R.; Weis, W.I. Scientific Reports 9, 2045-2322 (2019).
-
Structures of neurexophilin-neurexin complexes reveal a regulatory mechanism of alternative splicing.
Wilson, S.C.; White, I.; Zhou, Q.; Pfuetzner, R.A.; Choi, U.B.; Südhof, T.C.; Brunger, A.T. EMBO J , e101603 (2019).
-
Interparticle Interactions in Dilute Solutions of Polyelectrolyte Complex Micelles
Wu, H.; Ting, J.M.; Weiss, T.M.; Tirrell, M.V. ACS Macro Lett 8, 819-825 (2019).
-
Quaternary structure of α-amino-β-carboxymuconate-ϵ-semialdehyde decarboxylase (ACMSD) controls its activity.
Yang, Y.; Davis, I.; Matsui, T.; Rubalcava, I.; Liu, A. J Biol Chem 294, 11609-11621 (2019).
-
Disassociation and Reformation Under Strain in Polymer with Dynamic Metal–Ligand Coordination Cross-Linking
Zhang, Q.; Zhu, X.; Li, C.H.; Cai, Y.; Jia, X.; Bao, Z. Macromolecules 52, 660-668 (2019).
-
Mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector.
Akturk, A.; Wasilko, D.J.; Wu, X.; Liu, Y.; Zhang, Y.; Qiu, J.; Luo, Z.Q.; Reiter, K.H.; Brzovic, P.S.; Klevit, R.E.; Mao, Y. Nature 557, 729-733 (2018).
-
Molecular Engineering as an Approach To Modulate Gene Delivery Efficiency of Peptide-Modified Gemini Surfactants.
Al-Dulaymi, M.; Michel, D.; Chitanda, J.M.; El-Aneed, A.; Verrall, R.E.; Grochulski, P.; Badea, I. Bioconjug Chem 29, 3293-3308 (2018).
-
Structural and functional delineation of aerobactin biosynthesis in hypervirulent .
Bailey, D.C.; Alexander, E.; Rice, M.R.; Drake, E.J.; Mydy, L.S.; Aldrich, C.C.; Gulick, A.M. J Biol Chem 293, 7841-7852 (2018).
-
Comparison between 102k and 20k Poly(ethylene oxide) Depletants in Osmotic Pressure Measurements of Interfilament Forces in Cytoskeletal Systems
Chung, P.J.; Song, C.; Deek, J.; Miller, H.P.; Li, Y.; Choi, M.Chul; Wilson, L.; Feinstein, S.C.; Safinya, C.R. ACS Macro Lett 7, 228-232 (2018).
-
EpCAM homo-oligomerization is not the basis for its role in cell-cell adhesion.
Gaber, A.; Kim, S.Joong; Kaake, R.M.; Benčina, M.; Krogan, N.; Sali, A.; Pavšič, M.; Lenarčič, B. Sci Rep 8, 13269 (2018).
-
Polyion Charge Ratio Determines Transition between Bright and Dark Excitons in Donor/Acceptor-Conjugated Polyelectrolyte Complexes
Hollingsworth, W.R.; Magnanelli, T.J.; Segura, C.; Young, J.D.; Bragg, A.E.; Ayzner, A.L. J. Phys. Chem. C 122, 22280-22293 (2018).
-
Integrative structure and functional anatomy of a nuclear pore complex.
Kim, S.Joong; Fernandez-Martinez, J.; Nudelman, I.; Shi, Y.; Zhang, W.; Raveh, B.; Herricks, T.; Slaughter, B.D.; Hogan, J.A.; Upla, P.; Chemmama, I.E.; Pellarin, R.; Echeverria, I.; Shivaraju, M.; Chaudhury, A.S.; Wang, J.; Williams, R.; Unruh, J.R.; Greenberg, C.H.; Jacobs, E.Y.; Yu, Z.; de la Cruz, J.; Mironska, R.; Stokes, D.L.; Aitchison, J.D.; Jarrold, M.F.; Gerton, J.L.; Ludtke, S.J.; Akey, C.W.; Chait, B.T.; Sali, A.; Rout, M.P. Nature 555, 475-482 (2018).
-
The L Phase of Pulmonary Surfactant.
Kumar, K.; Chavarha, M.; Loney, R.W.; Weiss, T.M.; Rananavare, S.B.; Hall, S.B. Langmuir 34, 6601-6611 (2018).
-
A viral-fusion-peptide-like molecular switch drives membrane insertion of botulinum neurotoxin A1.
Lam, K.H.; Guo, Z.; Krez, N.; Matsui, T.; Perry, K.; Weisemann, J.; Rummel, A.; Bowen, M.E.; Jin, R. Nat Commun 9, 5367 (2018).
-
Machine learning-enabled discovery and design of membrane-active peptides.
Lee, E.Y.; Wong, G.C.L.; Ferguson, A.L. Bioorg Med Chem 26, 2708-2718 (2018).
-
Modulation of toll-like receptor signaling by antimicrobial peptides.
Lee, E.Y.; Lee, M.W.; Wong, G.C.L. Semin Cell Dev Biol , (2018).
-
What Can Pleiotropic Proteins in Innate Immunity Teach Us about Bioconjugation and Molecular Design?
Lee, M.W.; Lee, E.Y.; Wong, G.C.L. Bioconjug Chem 29, 2127-2139 (2018).
-
Discovery and Characterization of a Thioesterase-Specific Monoclonal Antibody That Recognizes the 6-Deoxyerythronolide B Synthase.
Li, X.; Sevillano, N.; La Greca, F.; Hsu, J.; Mathews, I.I.; Matsui, T.; Craik, C.S.; Khosla, C. Biochemistry 57, 6201-6208 (2018).
-
Structure-Function Analysis of the Extended Conformation of a Polyketide Synthase Module.
Li, X.; Sevillano, N.; La Greca, F.; Deis, L.; Liu, Y.C.; Deller, M.C.; Mathews, I.I.; Matsui, T.; Cane, D.E.; Craik, C.S.; Khosla, C. J Am Chem Soc 140, 6518-6521 (2018).
-
Structure and mechanism of a bacterial t6A biosynthesis system.
Luthra, A.; Swinehart, W.; Bayooz, S.; Phan, P.; Stec, B.; Iwata-Reuyl, D.; Swairjo, M.A. Nucleic Acids Res 46, 1395-1411 (2018).
-
Inhibitor potency varies widely among tumor-relevant human isocitrate dehydrogenase 1 mutants.
Matteo, D.Avellaneda; Wells, G.A.; Luna, L.A.; Grunseth, A.J.; Zagnitko, O.; Scott, D.A.; Hoang, A.; Luthra, A.; Swairjo, M.A.; Schiffer, J.M.; Sohl, C.D. Biochem J 475, 3221-3238 (2018).
-
Design and Evaluation of Gemini Surfactant-Based Lipoplexes Modified with Cell-Binding Peptide for Targeted Gene Therapy in Melanoma Model.
Mohammed-Saeid, W.; Soudy, R.; Tikoo, R.; Kaur, K.; Verrall, R.E.; Badea, I. J Pharm Pharm Sci 21, 363-375 (2018).
-
An N-terminally truncated form of cyclic GMP-dependent protein kinase Iα (PKG Iα) is monomeric and autoinhibited and provides a model for activation.
Moon, T.M.; Sheehe, J.L.; Nukareddy, P.; Nausch, L.W.; Wohlfahrt, J.; Matthews, D.E.; Blumenthal, D.K.; Dostmann, W.R. J Biol Chem 293, 7916-7929 (2018).
-
Ladderane phospholipids form a densely packed membrane with normal hydrazine and anomalously low proton/hydroxide permeability.
Moss, F.R.; Shuken, S.R.; Mercer, J.A.M.; Cohen, C.M.; Weiss, T.M.; Boxer, S.G.; Burns, N.Z. Proc Natl Acad Sci U S A 115, 9098-9103 (2018).
-
α-Catenin Structure and Nanoscale Dynamics in Solution and in Complex with F-Actin.
Nicholl, I.D.; Matsui, T.; Weiss, T.M.; Stanley, C.B.; Heller, W.T.; Martel, A.; Farago, B.; Callaway, D.J.E.; Bu, Z. Biophys J 115, 642-654 (2018).
-
A long-lived Aβ oligomer resistant to fibrillization.
Nick, M.; Wu, Y.; Schmidt, N.W.; Prusiner, S.B.; Stöhr, J.; Degrado, W.F. Biopolymers , (2018).
-
Absence of Mixed Phase in Organic Photovoltaic Active Layers Facilitates Use of Green Solvent Processing
Oosterhout, S.D.; Savikhin, V.; Burgers, M.A.; Zhang, J.; Zhang, Y.; Marder, S.R.; Bazan, G.C.; Toney, M.F. J. Phys. Chem. C 122, 11136-11144 (2018).
-
Intrinsic disorder in the regulatory N-terminal domain of diacylglycerol acyltransferase 1 from Brassica napus.
Panigrahi, R.; Matsui, T.; Song, A.H.; Caldo, K.Mark P.; Young, H.S.; Weselake, R.J.; Lemieux, J. Sci Rep 8, 16665 (2018).
-
Carbon Nanotube Porins in Amphiphilic Block Copolymers as Fully Synthetic Mimics of Biological Membranes.
Sanborn, J.R.; Chen, X.; Yao, Y.C.; Hammons, J.A.; Tunuguntla, R.H.; Zhang, Y.; Newcomb, C.C.; Soltis, J.A.; De Yoreo, J.J.; Van Buuren, A.; Parikh, A.N.; Noy, A. Adv Mater 30, e1803355 (2018).
-
Self-Assembly of a Designed Nucleoprotein Architecture through Multimodal Interactions.
Subramanian, R.H.; Smith, S.J.; Alberstein, R.G.; Bailey, J.B.; Zhang, L.; Cardone, G.; Suominen, L.; Chami, M.; Stahlberg, H.; Baker, T.S.; Tezcan, A. ACS Cent Sci 4, 1578-1586 (2018).
-
Cathelicidin promotes inflammation by enabling binding of self-RNA to cell surface scavenger receptors.
Takahashi, T.; Kulkarni, N.Nitin; Lee, E.Y.; Zhang, L.J.; Wong, G.C.L.; Gallo, R.L. Sci Rep 8, 4032 (2018).
-
Synthesis and Assembly of Designer Styrenic Diblock Polyelectrolytes
Ting, J.M.; Wu, H.; Herzog-Arbeitman, A.; Srivastava, S.; Tirrell, M.V. ACS Macro Letters 7, 726-733 (2018).
-
Cluster Size and Quinary Structure Determine the Rheological Effects of Antibody Self-Association at High Concentrations.
Wang, W.; Lilyestrom, W.G.; Hu, Z.Yu; Scherer, T.M. J Phys Chem B 122, 2138-2154 (2018).
-
De Novo Design and Implementation of a Tandem Acyl Carrier Protein Domain in a Type I Modular Polyketide Synthase.
Wang, Z.; Bagde, S.R.; Zavala, G.; Matsui, T.; Chen, X.; Kim, C.Y. ACS Chem Biol 13, 3072-3077 (2018).
-
Quadruple H-Bonding Cross-Linked Supramolecular Polymeric Materials as Substrates for Stretchable, Antitearing, and Self-Healable Thin Film Electrodes.
Yan, X.; Liu, Z.; Zhang, Q.; Lopez, J.; Wang, H.; Wu, H.C.; Niu, S.; Yan, H.; Wang, S.; Lei, T.; Li, J.; Qi, D.; Huang, P.; Huang, J.; Zhang, Y.; Wang, Y.; Li, G.; Tok, J.B.H.; Chen, X.; Bao, Z. J Am Chem Soc 140, 5280-5289 (2018).
-
Resonant Soft X-Ray Scattering Provides Protein Structure with Chemical Specificity.
Ye, D.; Le, T.P.; Kuei, B.; Zhu, C.; Zwart, P.H.; Wang, C.; Gomez, E.D.; Gomez, E.W. Structure 26, 1513-1521.e3 (2018).
-
Integrative Structural Investigation on the Architecture of Human Importin4_Histone H3/H4_Asf1a Complex and Its Histone H3 Tail Binding.
Yoon, J.; Kim, S.Joong; An, S.; Cho, S.; Leitner, A.; Jung, T.; Aebersold, R.; Hebert, H.; Cho, U.S.; Song, J.J. J Mol Biol 430, 822-841 (2018).
-
Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites
Yoshizawa, T.; Ali, R.; Jiou, J.; Fung, H.Y.J.; Burke, K.A.; Kim, S.J.; Lin, Y.; Peeples, W.B.; Saltzberg, D.; Soniat, M.; Baumhardt, J.M.; Oldenbourg, R.; Sali, A.; Fawzi, N.L.; Rosen, M.K.; Chook, Y.M. Cell 173, 693-705.e22 (2018).
-
Recording and Analyzing Nucleic Acid Distance Distributions with X-Ray Scattering Interferometry (XSI).
Zettl, T.; Das, R.; Harbury, P.A.B.; Herschlag, D.; Lipfert, J.; Mathew, R.S.; Shi, X. Curr Protoc Nucleic Acid Chem 73, e54 (2018).
-
Gold nanocrystal labels provide a sequence-to-3D structure map in SAXS reconstructions.
Zettl, T.; Mathew, R.S.; Shi, X.; Doniach, S.; Herschlag, D.; Harbury, P.A.B.; Lipfert, J. Sci Adv 4, eaar4418 (2018).
-
Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy.
Blocquel, D.; Li, S.; Wei, N.; Daub, H.; Sajish, M.; Erfurth, M.L.; Kooi, G.; Zhou, J.; Bai, G.; Schimmel, P.; Jordanova, A.; Yang, X.L. Nucleic Acids Res 45, 8091-8104 (2017).
-
Controllable Activation of Nanoscale Dynamics in a Disordered Protein Alters Binding Kinetics.
Callaway, D.J.E.; Matsui, T.; Weiss, T.; Stingaciu, L.R.; Stanley, C.B.; Heller, W.T.; Bu, Z. J Mol Biol 429, 987-998 (2017).
-
Phospho-Priming Confers Functionally Relevant Specificities for Rad53 Kinase Autophosphorylation.
Chen, E.ShengWen; Weng, J.H.; Chen, Y.H.; Wang, S.C.; Liu, X.X.; Huang, W.C.; Matsui, T.; Kawano, Y.; Liao, J.H.; Lim, L.H.; Bessho, Y.; Huang, K.F.; Wu, W.J.; Tsai, M.D. Biochemistry 56, 5112-5124 (2017).
-
Paclitaxel suppresses Tau-mediated microtubule bundling in a concentration-dependent manner.
Choi, M.Chul; Chung, P.J.; Song, C.; Miller, H.P.; Kiris, E.; Li, Y.; Wilson, L.; Feinstein, S.C.; Safinya, C.R. Biochim Biophys Acta 1861, 3456-3463 (2017).
-
Synchrotron small-angle X-ray scattering and electron microscopy characterization of structures and forces in microtubule/Tau mixtures.
Chung, P.J.; Song, C.; Miller, H.P.; Li, Y.; Raviv, U.; Choi, M.Chul; Wilson, L.; Feinstein, S.C.; Safinya, C.R. Methods Cell Biol 141, 155-178 (2017).
-
Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization.
de la Peña, A.Torrents; Julien, J.P.; de Taeye, S.W.; Garces, F.; Guttman, M.; Ozorowski, G.; Pritchard, L.K.; Behrens, A.J.; Go, E.P.; Burger, J.A.; Schermer, E.E.; Sliepen, K.; Ketas, T.J.; Pugach, P.; Yasmeen, A.; Cottrell, C.A.; Torres, J.L.; Vavourakis, C.D.; van Gils, M.J.; LaBranche, C.; Montefiori, D.C.; Desaire, H.; Crispin, M.; Klasse, P.Johan; Lee, K.K.; Moore, J.P.; Ward, A.B.; Wilson, I.A.; Sanders, R.W. Cell Rep 20, 1805-1817 (2017).
-
Internal Structure and Preferential Protein Binding of Colloidal Aggregates.
Duan, D.; Torosyan, H.; Elnatan, D.; McLaughlin, C.K.; Logie, J.; Shoichet, M.S.; Agard, D.A.; Shoichet, B.K. ACS Chem Biol 12, 282-290 (2017).
-
Environmental Calcium Controls Alternate Physical States of the Caulobacter Surface Layer.
Herrmann, J.; Jabbarpour, F.; Bargar, P.G.; Nomellini, J.F.; Li, P.N.; Lane, T.J.; Weiss, T.M.; Smit, J.; Shapiro, L.; Wakatsuki, S. Biophys J 112, 1841-1851 (2017).
-
Hydrophilic Phage-Mimicking Membrane Active Antimicrobials Reveal Nanostructure-Dependent Activity and Selectivity.
Jiang, Y.; Zheng, W.; Kuang, L.; Ma, H.; Liang, H. ACS Infect Dis 3, 676-687 (2017).
-
Structural and functional characterization of α-catenin reveals constitutive binding to β-catenin and F-actin.
Kang, H.; Bang, I.; Jin, K.Sik; Lee, B.; Lee, J.; Shao, X.; Heier, J.A.; Kwiatkowski, A.V.; Nelson, J.; Hardin, J.; Weis, W.I.; Choi, H.J. J Biol Chem 292, 7077-7086 (2017).
-
Direct Antimicrobial Activity of IFN-β.
Kaplan, A.; Lee, M.W.; Wolf, A.J.; Limon, J.J.; Becker, C.A.; Ding, M.; Murali, R.; Lee, E.Y.; Liu, G.Y.; Wong, G.C.L.; Underhill, D.M. J Immunol 198, 4036-4045 (2017).
-
Crystallinity of Double-Stranded RNA-Antimicrobial Peptide Complexes Modulates Toll-Like Receptor 3-Mediated Inflammation.
Lee, E.Y.; Takahashi, T.; Curk, T.; Dobnikar, J.; Gallo, R.L.; Wong, G.C.L. ACS Nano 11, 12145-12155 (2017).
-
What can machine learning do for antimicrobial peptides, and what can antimicrobial peptides do for machine learning?
Lee, E.Y.; Lee, M.W.; Fulan, B.M.; Ferguson, A.L.; Wong, G.C.L. Interface Focus 7, 20160153 (2017).
-
Structural features of NS3 of Dengue virus serotypes 2 and 4 in solution and insight into RNA binding and the inhibitory role of quercetin.
Pan, A.; Saw, W.Geok; Manimekalai, M.Sony Subra; Grüber, A.; Joon, S.; Matsui, T.; Weiss, T.M.; Grüber, G. Acta Crystallogr D Struct Biol 73, 402-419 (2017).
-
Plasmon-actuated nano-assembled microshells.
Quint, M.T.; Sarang, S.; Quint, D.A.; Keshavarz, A.; Stokes, B.J.; Subramaniam, A.Bala; Huang, K.Casey; Gopinathan, A.; Hirst, L.S.; Ghosh, S. Sci Rep 7, 17788 (2017).
-
Determination of the conformational ensemble of the TAR RNA by X-ray scattering interferometry.
Shi, X.; Walker, P.; Harbury, P.B.; Herschlag, D. Nucleic Acids Res 45, e64 (2017).
-
Distinct solubility and cytotoxicity regimes of paclitaxel-loaded cationic liposomes at low and high drug content revealed by kinetic phase behavior and cancer cell viability studies.
Steffes, V.M.; Murali, M.M.; Park, Y.; Fletcher, B.J.; Ewert, K.K.; Safinya, C.R. Biomaterials 145, 242-255 (2017).
-
Bacterial amyloid curli acts as a carrier for DNA to elicit an autoimmune response via TLR2 and TLR9.
Tursi, S.A.; Lee, E.Y.; Medeiros, N.J.; Lee, M.H.; Nicastro, L.K.; Buttaro, B.; Gallucci, S.; Wilson, R.Paul; Wong, G.C.L.; Tükel, Ç. PLoS Pathog 13, e1006315 (2017).
-
Molecular Architecture of the Major Membrane Ring Component of the Nuclear Pore Complex.
Upla, P.; Kim, S.Joong; Sampathkumar, P.; Dutta, K.; Cahill, S.M.; Chemmama, I.E.; Williams, R.; Bonanno, J.B.; Rice, W.J.; Stokes, D.L.; Cowburn, D.; Almo, S.C.; Sali, A.; Rout, M.P.; Fernandez-Martinez, J. Structure 25, 434-445 (2017).
-
The molecular architecture of the yeast spindle pole body core determined by Bayesian integrative modeling.
Viswanath, S.; Bonomi, M.; Kim, S.Joong; Klenchin, V.A.; Taylor, K.C.; Yabut, K.C.; Umbreit, N.T.; Van Epps, H.A.; Meehl, J.; Jones, M.H.; Russel, D.; Velazquez-Muriel, J.A.; Winey, M.; Rayment, I.; Davis, T.N.; Sali, A.; Muller, E.G. Mol Biol Cell 28, 3298-3314 (2017).
-
Dynamic intramolecular regulation of the histone chaperone nucleoplasmin controls histone binding and release.
Warren, C.; Matsui, T.; Karp, J.M.; Onikubo, T.; Cahill, S.; Brenowitz, M.; Cowburn, D.; Girvin, M.; Shechter, D. Nat Commun 8, 2215 (2017).
-
Di-Peptide-Modified Gemini Surfactants as Gene Delivery Vectors: Exploring the Role of the Alkyl Tail in Their Physicochemical Behavior and Biological Activity.
Al-Dulaymi, M.A.; Chitanda, J.M.; Mohammed-Saeid, W.; Araghi, H.Younesi; Verrall, R.E.; Grochulski, P.; Badea, I. AAPS J 18, 1168-81 (2016).
-
Structure and mechanism of a molecular rheostat, an RNA thermometer that modulates immune evasion by Neisseria meningitidis.
Barnwal, R.Pratap; Loh, E.; Godin, K.S.; Yip, J.; Lavender, H.; Tang, C.M.; Varani, G. Nucleic Acids Res 44, 9426-9437 (2016).
-
A Usual G-Protein-Coupled Receptor in Unusual Membranes.
Chawla, U.; Jiang, Y.; Zheng, W.; Kuang, L.; Perera, S.M.D.C.; Pitman, M.C.; Brown, M.F.; Liang, H. Angew Chem Int Ed Engl 55, 588-92 (2016).
-
Tau mediates microtubule bundle architectures mimicking fascicles of microtubules found in the axon initial segment.
Chung, P.J.; Song, C.; Deek, J.; Miller, H.P.; Li, Y.; Choi, M.Chul; Wilson, L.; Feinstein, S.C.; Safinya, C.R. Nat Commun 7, 12278 (2016).
-
Neurofilament networks: Salt-responsive hydrogels with sidearm-dependent phase behavior.
Deek, J.; Chung, P.J.; Safinya, C.R. Biochim Biophys Acta 1860, 1560-9 (2016).
-
Structure and Function of the Nuclear Pore Complex Cytoplasmic mRNA Export Platform.
Fernandez-Martinez, J.; Kim, S.Joong; Shi, Y.; Upla, P.; Pellarin, R.; Gagnon, M.; Chemmama, I.E.; Wang, J.; Nudelman, I.; Zhang, W.; Williams, R.; Rice, W.J.; Stokes, D.L.; Zenklusen, D.; Chait, B.T.; Sali, A.; Rout, M.P. Cell 167, 1215-1228.e25 (2016).
-
Structure of the Intermediate Filament-Binding Region of Desmoplakin.
Kang, H.; Weiss, T.M.; Bang, I.; Weis, W.I.; Choi, H.J. PLoS One 11, e0147641 (2016).
-
Mapping membrane activity in undiscovered peptide sequence space using machine learning.
Lee, E.Y.; Fulan, B.M.; Wong, G.C.L.; Ferguson, A.L. Proc Natl Acad Sci U S A 113, 13588-13593 (2016).
-
A review of immune amplification via ligand clustering by self-assembled liquid-crystalline DNA complexes.
Lee, E.Y.; Lee, C.K.; Schmidt, N.W.; Jin, F.; Lande, R.; Curk, T.; Frenkel, D.; Dobnikar, J.; Gilliet, M.; Wong, G.C.L. Adv Colloid Interface Sci 232, 17-24 (2016).
-
Changes in Structure and Antigenicity of HIV-1 Env Trimers Resulting from Removal of a Conserved CD4 Binding Site-Proximal Glycan.
Liang, Y.; Guttman, M.; Williams, J.A.; Verkerke, H.; Alvarado, D.; Hu, S.L.; Lee, K.K. J Virol 90, 9224-36 (2016).
-
Probing the Impact of Local Structural Dynamics of Conformational Epitopes on Antibody Recognition.
Liang, Y.; Guttman, M.; Davenport, T.M.; Hu, S.L.; Lee, K.K. Biochemistry 55, 2197-213 (2016).
-
Novel Features of DAG-Activated PKC Isozymes Reveal a Conserved 3-D Architecture.
Lučić, I.; Truebestein, L.; Leonard, T.A. J Mol Biol 428, 121-141 (2016).
-
Selective Binding of AIRAPL Tandem UIMs to Lys48-Linked Tri-Ubiquitin Chains.
Rahighi, S.; Braunstein, I.; Ternette, N.; Kessler, B.; Kawasaki, M.; Kato, R.; Matsui, T.; Weiss, T.M.; Stanhill, A.; Wakatsuki, S. Structure 24, 412-22 (2016).
-
Stretchable Self-Healing Polymeric Dielectrics Cross-Linked Through Metal-Ligand Coordination.
Rao, Y.L.; Chortos, A.; Pfattner, R.; Lissel, F.; Chiu, Y.C.; Feig, V.; Xu, J.; Kurosawa, T.; Gu, X.; Wang, C.; He, M.; Chung, J.Won; Bao, Z. J Am Chem Soc 138, 6020-7 (2016).
-
The effect of multivalent cations and Tau on paclitaxel-stabilized microtubule assembly, disassembly, and structure.
Safinya, C.R.; Chung, P.J.; Song, C.; Li, Y.; Ewert, K.K.; Choi, M.Chul Adv Colloid Interface Sci 232, 9-16 (2016).
-
Oxidation of Membrane Curvature-Regulating Phosphatidylethanolamine Lipid Results in Formation of Bilayer and Cubic Structures.
Sankhagowit, S.; Lee, E.Y.; Wong, G.C.L.; Malmstadt, N. Langmuir 32, 2450-7 (2016).
-
The solution structural ensembles of RNA kink-turn motifs and their protein complexes.
Shi, X.; Huang, L.; Lilley, D.M.J.; Harbury, P.B.; Herschlag, D. Nat Chem Biol 12, 146-52 (2016).
-
Two crystal structures reveal design for repurposing the C-Ala domain of human AlaRS.
Sun, L.; Song, Y.; Blocquel, D.; Yang, X.L.; Schimmel, P. Proc Natl Acad Sci U S A 113, 14300-14305 (2016).
-
Simple rules for passive diffusion through the nuclear pore complex.
Timney, B.L.; Raveh, B.; Mironska, R.; Trivedi, J.M.; Kim, S.Joong; Russel, D.; Wente, S.R.; Sali, A.; Rout, M.P. J Cell Biol 215, 57-76 (2016).
-
Solution structure of an "open" E. coli Pol III clamp loader sliding clamp complex.
Tondnevis, F.; Weiss, T.M.; Matsui, T.; Bloom, L.B.; McKenna, R. J Struct Biol 194, 272-81 (2016).
-
Structure of Carbon Nanotube Porins in Lipid Bilayers: An in Situ Small-Angle X-ray Scattering (SAXS) Study.
Tran, I.C.; Tunuguntla, R.H.; Kim, K.; Lee, J.R.I.; Willey, T.M.; Weiss, T.M.; Noy, A.; van Buuren, T. Nano Lett 16, 4019-24 (2016).
-
Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein.
Tuttle, M.D.; Comellas, G.; Nieuwkoop, A.J.; Covell, D.J.; Berthold, D.A.; Kloepper, K.D.; Courtney, J.M.; Kim, J.K.; Barclay, A.M.; Kendall, A.; Wan, W.; Stubbs, G.; Schwieters, C.D.; M Y Lee, V.; George, J.M.; Rienstra, C.M. Nat Struct Mol Biol 23, 409-15 (2016).
-
Structure and Dynamics of Extracellular Loops in Human Aquaporin-1 from Solid-State NMR and Molecular Dynamics.
Wang, S.; Ing, C.; Emami, S.; Jiang, Y.; Liang, H.; Pomès, R.; Brown, L.S.; Ladizhansky, V. J Phys Chem B 120, 9887-902 (2016).
-
Structure of a Bacterial Virus DNA-Injection Protein Complex Reveals a Decameric Assembly with a Constricted Molecular Channel.
Zhao, H.; Speir, J.A.; Matsui, T.; Lin, Z.; Liang, L.; Lynn, A.Y.; Varnado, B.; Weiss, T.M.; Tang, L. PLoS One 11, e0149337 (2016).
-
Magnetic field induced quantum dot brightening in liquid crystal synergized magnetic and semiconducting nanoparticle composite assemblies.
Amaral, J.Jussi; Wan, J.; Rodarte, A.L.; Ferri, C.; Quint, M.T.; Pandolfi, R.J.; Scheibner, M.; Hirst, L.S.; Ghosh, S. Soft Matter 11, 255-60 (2015).
-
Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition.
Bonora, M.; Wieckowsk, M.R.; Chinopoulos, C.; Kepp, O.; Kroemer, G.; Galluzzi, L.; Pinton, P. Oncogene 34, 1608 (2015).
-
Prion Protein-Antibody Complexes Characterized by Chromatography-Coupled Small-Angle X-Ray Scattering.
Carter, L.; Kim, S.Joong; Schneidman-Duhovny, D.; Stöhr, J.; Poncet-Montange, G.; Weiss, T.M.; Tsuruta, H.; Prusiner, S.B.; Sali, A. Biophys J 109, 793-805 (2015).
-
Long-range ion-water and ion-ion interactions in aqueous solutions.
Chen, C.; Huang, C.; Waluyo, I.; Weiss, T.; Pettersson, L.G.M.; Nilsson, A. Phys Chem Chem Phys 17, 8427-30 (2015).
-
Direct force measurements reveal that protein Tau confers short-range attractions and isoform-dependent steric stabilization to microtubules.
Chung, P.J.; Choi, M.Chul; Miller, H.P.; Feinstein, E.; Raviv, U.; Li, Y.; Wilson, L.; Feinstein, S.C.; Safinya, C.R. Proc Natl Acad Sci U S A 112, E6416-25 (2015).
-
Impact of phospholipids on plasmid packaging and toxicity of gemini nanoparticles.
Dong, C.; Badea, I.; Poorghorban, M.; Verrall, R.; Foldvari, M. J Mater Chem B 3, 8806-8822 (2015).
-
Structural Variations and Solvent Structure of r(UGGGGU) Quadruplexes Stabilized by Sr(2+) Ions.
Fyfe, A.C.; Dunten, P.W.; Martick, M.M.; Scott, W.G. J Mol Biol 427, 2205-19 (2015).
-
Dynamic changes during acid-induced activation of influenza hemagglutinin.
Garcia, N.K.; Guttman, M.; Ebner, J.L.; Lee, K.K. Structure 23, 665-76 (2015).
-
The accurate assessment of small-angle X-ray scattering data.
Grant, T.D.; Luft, J.R.; Carter, L.G.; Matsui, T.; Weiss, T.M.; Martel, A.; Snell, E.H. Acta Crystallogr D Biol Crystallogr 71, 45-56 (2015).
-
Local and global structural drivers for the photoactivation of the orange carotenoid protein.
Gupta, S.; Guttman, M.; Leverenz, R.L.; Zhumadilova, K.; Pawlowski, E.G.; Petzold, C.J.; Lee, K.K.; Ralston, C.Y.; Kerfeld, C.A. Proc Natl Acad Sci U S A 112, E5567-74 (2015).
-
Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with αα Domain Architecture That Catalyzes a Unique Cyclization-Fragmentation Reaction Sequence.
Harris, G.G.; Lombardi, P.M.; Pemberton, T.A.; Matsui, T.; Weiss, T.M.; Cole, K.E.; Köksal, M.; Murphy, F.V.; Vedula, S.; Chou, W.K.W.; Cane, D.E.; Christianson, D.W. Biochemistry 54, 7142-55 (2015).
-
Small-Anion Selective Transmembrane "Holes" Induced by an Antimicrobial Peptide Too Short to Span Membranes.
Hu, K.; Jiang, Y.; Xie, Y.; Liu, H.; Liu, R.; Zhao, Z.; Lai, R.; Yang, L. J Phys Chem B 119, 8553-60 (2015).
-
PqqD is a novel peptide chaperone that forms a ternary complex with the radical S-adenosylmethionine protein PqqE in the pyrroloquinoline quinone biosynthetic pathway.
Latham, J.A.; Iavarone, A.T.; Barr, I.; Juthani, P.V.; Klinman, J.P. J Biol Chem 290, 12908-18 (2015).
-
Ordering in bio-inorganic hybrid nanomaterials probed by in situ scanning transmission X-ray microscopy.
Lee, J.R.I.; Bagge-Hansen, M.; Tunuguntla, R.; Kim, K.; Bangar, M.; Willey, T.M.; Tran, I.C.; Kilcoyne, D.A.; Noy, A.; van Buuren, T. Nanoscale 7, 9477-86 (2015).
-
Protein Arginine Methyltransferase 8: Tetrameric Structure and Protein Substrate Specificity.
Lee, W.C.; Lin, W.L.; Matsui, T.; Chen, E.S.W.; Wei, T.Y.Wade; Lin, W.H.; Hu, H.; Zheng, Y.George; Tsai, M.D.; Ho, M.C. Biochemistry 54, 7514-23 (2015).
-
Assembly and Molecular Architecture of the Phosphoinositide 3-Kinase p85α Homodimer.
LoPiccolo, J.; Kim, S.Joong; Shi, Y.; Wu, B.; Wu, H.; Chait, B.T.; Singer, R.H.; Sali, A.; Brenowitz, M.; Bresnick, A.R.; Backer, J.M. J Biol Chem 290, 30390-405 (2015).
-
Effects of Low Concentrations of Docosahexaenoic Acid on the Structure and Phase Behavior of Model Lipid Membranes.
Lor, C.; Hirst, L.S. Membranes (Basel) 5, 857-74 (2015).
-
An encapsidated viral protein and its role in RNA packaging by a non-enveloped animal RNA virus.
Mendes, A.; Vlok, M.; Short, J.R.; Matsui, T.; Dorrington, R.A. Virology 476, 323-333 (2015).
-
The structure of the PanD/PanZ protein complex reveals negative feedback regulation of pantothenate biosynthesis by coenzyme A.
Monteiro, D.C.F.; Patel, V.; Bartlett, C.P.; Nozaki, S.; Grant, T.D.; Gowdy, J.A.; Thompson, G.S.; Kalverda, A.P.; Snell, E.H.; Niki, H.; Pearson, A.R.; Webb, M.E. Chem Biol 22, 492-503 (2015).
-
Anti-PolyQ Antibodies Recognize a Short PolyQ Stretch in Both Normal and Mutant Huntingtin Exon 1.
Owens, G.E.; New, D.M.; West, A.P.; Bjorkman, P.J. J Mol Biol 427, 2507-2519 (2015).
-
Characterization of the host-guest complex of a curcumin analog with β-cyclodextrin and β-cyclodextrin-gemini surfactant and evaluation of its anticancer activity.
Poorghorban, M.; Das, U.; Alaidi, O.; Chitanda, J.M.; Michel, D.; Dimmock, J.; Verrall, R.; Grochulski, P.; Badea, I. Int J Nanomedicine 10, 503-15 (2015).
-
Self-assembled nanoparticle micro-shells templated by liquid crystal sorting.
Rodarte, A.L.; Cao, B.H.; Panesar, H.; Pandolfi, R.J.; Quint, M.; Edwards, L.; Ghosh, S.; Hein, J.E.; Hirst, L.S. Soft Matter 11, 1701-7 (2015).
-
Structural insight and flexible features of NS5 proteins from all four serotypes of Dengue virus in solution.
Saw, W.Geok; Tria, G.; Grüber, A.; Manimekalai, M.Sony Subra; Zhao, Y.; Chandramohan, A.; Anand, G.Srinivasan; Matsui, T.; Weiss, T.M.; Vasudevan, S.G.; Grüber, G. Acta Crystallogr D Biol Crystallogr 71, 2309-27 (2015).
-
Liquid-crystalline ordering of antimicrobial peptide-DNA complexes controls TLR9 activation.
Schmidt, N.W.; Jin, F.; Lande, R.; Curk, T.; Xian, W.; Lee, C.; Frasca, L.; Frenkel, D.; Dobnikar, J.; Gilliet, M.; Wong, G.C.L. Nat Mater 14, 696-700 (2015).
-
Quantifying Nucleic Acid Ensembles with X-ray Scattering Interferometry.
Shi, X.; Bonilla, S.; Herschlag, D.; Harbury, P. Methods Enzymol 558, 75-97 (2015).
-
Nematic director reorientation at solid and liquid interfaces under flow: SAXS studies in a microfluidic device.
Silva, B.F.B.; Zepeda-Rosales, M.; Venkateswaran, N.; Fletcher, B.J.; Carter, L.G.; Matsui, T.; Weiss, T.M.; Han, J.; Li, Y.; Olsson, U.; Safinya, C.R. Langmuir 31, 4361-71 (2015).
-
The Hsp104 N-terminal domain enables disaggregase plasticity and potentiation.
Sweeny, E.A.; Jackrel, M.E.; Go, M.S.; Sochor, M.A.; Razzo, B.M.; DeSantis, M.E.; Gupta, K.; Shorter, J. Mol Cell 57, 836-849 (2015).
-
Intrinsic disorder drives N-terminal ubiquitination by Ube2w.
Vittal, V.; Shi, L.; Wenzel, D.M.; Scaglione, M.; Duncan, E.D.; Basrur, V.; Elenitoba-Johnson, K.S.J.; Baker, D.; Paulson, H.L.; Brzovic, P.S.; Klevit, R.E. Nat Chem Biol 11, 83-9 (2015).
-
Structural studies of truncated forms of the prion protein PrP.
Wan, W.; Wille, H.; Stöhr, J.; Kendall, A.; Bian, W.; McDonald, M.; Tiggelaar, S.; Watts, J.C.; Prusiner, S.B.; Stubbs, G. Biophys J 108, 1548-1554 (2015).
-
Truncated forms of the prion protein PrP demonstrate the need for complexity in prion structure.
Wan, W.; Stöhr, J.; Kendall, A.; Stubbs, G. Prion 9, 333-8 (2015).
-
In situ structural studies of Anabaena sensory rhodopsin in the E. coli membrane.
Ward, M.E.; Wang, S.; Munro, R.; Ritz, E.; Hung, I.; Gor'kov, P.L.; Jiang, Y.; Liang, H.; Brown, L.S.; Ladizhansky, V. Biophys J 108, 1683-1696 (2015).
-
Helical antimicrobial polypeptides with radial amphiphilicity.
Xiong, M.; Lee, M.W.; Mansbach, R.A.; Song, Z.; Bao, Y.; Peek, R.M.; Yao, C.; Chen, L.F.; Ferguson, A.L.; Wong, G.C.L.; Cheng, J. Proc Natl Acad Sci U S A 112, 13155-60 (2015).
-
Viral fusion protein transmembrane domain adopts β-strand structure to facilitate membrane topological changes for virus-cell fusion.
Yao, H.; Lee, M.W.; Waring, A.J.; Wong, G.C.L.; Hong, M. Proc Natl Acad Sci U S A 112, 10926-31 (2015).
-
Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46.
Yin, J.P.; Schoeffler, A.J.; Wickliffe, K.; Newton, K.; Starovasnik, M.A.; Dueber, E.C.; Harris, S.F. Structure 23, 2043-54 (2015).
-
Molecular functions of the TLE tetramerization domain in Wnt target gene repression.
Chodaparambil, J.V.; Pate, K.T.; Hepler, M.R.D.; Tsai, B.P.; Muthurajan, U.M.; Luger, K.; Waterman, M.L.; Weis, W.I. EMBO J 33, 719-31 (2014).
-
Architectures of whole-module and bimodular proteins from the 6-deoxyerythronolide B synthase.
Edwards, A.L.; Matsui, T.; Weiss, T.M.; Khosla, C. J Mol Biol 426, 2229-45 (2014).
-
CD4-induced activation in a soluble HIV-1 Env trimer.
Guttman, M.; Garcia, N.K.; Cupo, A.; Matsui, T.; Julien, J.P.; Sanders, R.W.; Wilson, I.A.; Moore, J.P.; Lee, K.K. Structure 22, 974-84 (2014).
-
Integrative structure-function mapping of the nucleoporin Nup133 suggests a conserved mechanism for membrane anchoring of the nuclear pore complex.
Kim, S.Joong; Fernandez-Martinez, J.; Sampathkumar, P.; Martel, A.; Matsui, T.; Tsuruta, H.; Weiss, T.M.; Shi, Y.; Markina-Inarrairaegui, A.; Bonanno, J.B.; Sauder, M.; Burley, S.K.; Chait, B.T.; Almo, S.C.; Rout, M.P.; Sali, A. Mol Cell Proteomics 13, 2911-26 (2014).
-
Interface for Light-Driven Electron Transfer by Photosynthetic Complexes Across Block Copolymer Membranes.
Kuang, L.; Olson, T.L.; Lin, S.; Flores, M.; Jiang, Y.; Zheng, W.; Williams, J.A.C.; Allen, J.P.; Liang, H. J Phys Chem Lett 5, 787-91 (2014).
-
"Frozen" block copolymer nanomembranes with light-driven proton pumping performance.
Kuang, L.; Fernandes, D.A.; O'Halloran, M.; Zheng, W.; Jiang, Y.; Ladizhansky, V.; Brown, L.S.; Liang, H. ACS Nano 8, 537-45 (2014).
-
Two interdependent mechanisms of antimicrobial activity allow for efficient killing in nylon-3-based polymeric mimics of innate immunity peptides.
Lee, M.W.; Chakraborty, S.; Schmidt, N.W.; Murgai, R.; Gellman, S.H.; Wong, G.C.L. Biochim Biophys Acta 1838, 2269-79 (2014).
-
Structural basis of the pH-dependent assembly of a botulinum neurotoxin complex.
Matsui, T.; Gu, S.; Lam, K.H.; Carter, L.G.; Rummel, A.; Mathews, I.I.; Jin, R. J Mol Biol 426, 3773-3782 (2014).
-
Transformation of taxol-stabilized microtubules into inverted tubulin tubules triggered by a tubulin conformation switch.
Ojeda-Lopez, M.A.; Needleman, D.J.; Song, C.; Ginsburg, A.; Kohl, P.A.; Li, Y.; Miller, H.P.; Wilson, L.; Raviv, U.; Choi, M.Chul; Safinya, C.R. Nat Mater 13, 195-203 (2014).
-
Internal motions prime cIAP1 for rapid activation.
Phillips, A.H.; Schoeffler, A.J.; Matsui, T.; Weiss, T.M.; Blankenship, J.W.; Zobel, K.; Giannetti, A.M.; Dueber, E.C.; Fairbrother, W.J. Nat Struct Mol Biol 21, 1068-74 (2014).
-
Structure of Clostridium difficile PilJ exhibits unprecedented divergence from known type IV pilins.
Piepenbrink, K.H.; Maldarelli, G.A.; de la Peña, C.F.Martinez; Mulvey, G.L.; Snyder, G.A.; De Masi, L.; von Rosenvinge, E.C.; Günther, S.; Armstrong, G.D.; Donnenberg, M.S.; Sundberg, E.J. J Biol Chem 289, 4334-45 (2014).
-
Tuning quantum-dot organization in liquid crystals for robust photonic applications.
Rodarte, A.L.; Nuno, Z.S.; Cao, B.H.; Pandolfi, R.J.; Quint, M.T.; Ghosh, S.; Hein, J.E.; Hirst, L.S. Chemphyschem 15, 1413-21 (2014).
-
Cationic liposome-nucleic acid complexes for gene delivery and gene silencing.
Safinya, C.R.; Ewert, K.K.; Majzoub, R.N.; Leal, C. New J Chem 38, 5164-5172 (2014).
-
Engineering persister-specific antibiotics with synergistic antimicrobial functions.
Schmidt, N.W.; Deshayes, S.; Hawker, S.; Blacker, A.; Kasko, A.M.; Wong, G.C.L. ACS Nano 8, 8786-93 (2014).
-
A mechanistic understanding of processing additive-induced efficiency enhancement in bulk heterojunction organic solar cells.
Schmidt, K.; Tassone, C.J.; Niskala, J.R.; Yiu, A.T.; Lee, O.P.; Weiss, T.M.; Wang, C.; Fréchet, J.M.J.; Beaujuge, P.M.; Toney, M.F. Adv Mater 26, 300-5 (2014).
-
Ultrafast X-ray probing of water structure below the homogeneous ice nucleation temperature.
Sellberg, J.A.; Huang, C.; McQueen, T.A.; Loh, N.D.; Laksmono, H.; Schlesinger, D.; Sierra, R.G.; Nordlund, D.; Hampton, C.Y.; Starodub, D.; DePonte, D.P.; Beye, M.; Chen, C.; Martin, A.V.; Barty, A.; Wikfeldt, K.T.; Weiss, T.M.; Caronna, C.; Feldkamp, J.; Skinner, L.B.; Seibert, M.M.; Messerschmidt, M.; Williams, G.J.; Boutet, S.; Pettersson, L.G.M.; Bogan, M.J.; Nilsson, A. Nature 510, 381-4 (2014).
-
Glycosylation of Skp1 affects its conformation and promotes binding to a model f-box protein.
Sheikh, O.; Schafer, C.M.; Powell, J.T.; Rodgers, K.K.; Mooers, B.H.M.; West, C.M. Biochemistry 53, 1657-69 (2014).
-
From a structural average to the conformational ensemble of a DNA bulge.
Shi, X.; Beauchamp, K.A.; Harbury, P.B.; Herschlag, D. Proc Natl Acad Sci U S A 111, E1473-80 (2014).
-
PEGylated cationic liposome-DNA complexation in brine is pathway-dependent.
Silva, B.F.B.; Majzoub, R.N.; Chan, C.L.; Li, Y.; Olsson, U.; Safinya, C.R. Biochim Biophys Acta 1838, 398-412 (2014).
-
Structure of the bifunctional aminoglycoside-resistance enzyme AAC(6')-Ie-APH(2'')-Ia revealed by crystallographic and small-angle X-ray scattering analysis.
Smith, C.A.; Toth, M.; Weiss, T.M.; Frase, H.; Vakulenko, S.B. Acta Crystallogr D Biol Crystallogr 70, 2754-64 (2014).
-
Conformational analysis of the Streptococcus pneumoniae hyaluronate lyase and characterization of its hyaluronan-specific carbohydrate-binding module.
Suits, M.D.L.; Pluvinage, B.; Law, A.; Liu, Y.; Palma, A.S.; Chai, W.; Feizi, T.; Boraston, A.B. J Biol Chem 289, 27264-77 (2014).
-
Control of RecBCD enzyme activity by DNA binding- and Chi hotspot-dependent conformational changes.
Taylor, A.F.; Amundsen, S.K.; Guttman, M.; Lee, K.K.; Luo, J.; Ranish, J.; Smith, G.R. J Mol Biol 426, 3479-99 (2014).
-
Crystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodies.
Trastoy, B.; Lomino, J.V.; Pierce, B.G.; Carter, L.G.; Günther, S.; Giddens, J.P.; Snyder, G.A.; Weiss, T.M.; Weng, Z.; Wang, L.X.; Sundberg, E.J. Proc Natl Acad Sci U S A 111, 6714-9 (2014).
-
Fungal prion HET-s as a model for structural complexity and self-propagation in prions.
Wan, W.; Stubbs, G. Proc Natl Acad Sci U S A 111, 5201-6 (2014).
-
Fiber diffraction of the prion-forming domain HET-s(218-289) shows dehydration-induced deformation of a complex amyloid structure.
Wan, W.; Stubbs, G. Biochemistry 53, 2366-70 (2014).
-
Heterogeneous seeding of HET-s(218-289) and the mutability of prion structures.
Wan, W.; Stubbs, G. Prion 8, (2014).
-
Structural insights into omega-class glutathione transferases: a snapshot of enzyme reduction and identification of a non-catalytic ligandin site.
Brock, J.; Board, P.G.; Oakley, A.J. PLoS One 8, e60324 (2013).
-
Solvation structures of protons and hydroxide ions in water.
Chen, C.; Huang, C.; Waluyo, I.; Nordlund, D.; Weng, T.C.; Sokaras, D.; Weiss, T.; Bergmann, U.; Pettersson, L.G.M.; Nilsson, A. J Chem Phys 138, 154506 (2013).
-
Self-assembling semiconducting polymers--rods and gels from electronic materials.
Clark, A.P.Z.; Shi, C.; Ng, B.C.; Wilking, J.N.; Ayzner, A.L.; Stieg, A.Z.; Schwartz, B.J.; Mason, T.G.; Rubin, Y.; Tolbert, S.H. ACS Nano 7, 962-77 (2013).
-
Chemical speciation of neptunium(VI) under strongly alkaline conditions. Structure, composition, and oxo ligand exchange.
Clark, D.L.; Conradson, S.D.; Donohoe, R.J.; Gordon, P.L.; Keogh, W.; Palmer, P.D.; Scott, B.L.; Tait, D. Inorg Chem 52, 3547-55 (2013).
-
Syntaxin1a variants lacking an N-peptide or bearing the LE mutation bind to Munc18a in a closed conformation.
Colbert, K.N.; Hattendorf, D.A.; Weiss, T.M.; Burkhardt, P.; Fasshauer, D.; Weis, W.I. Proc Natl Acad Sci U S A 110, 12637-42 (2013).
-
Isolate-specific differences in the conformational dynamics and antigenicity of HIV-1 gp120.
Davenport, T.M.; Guttman, M.; Guo, W.; Cleveland, B.; Kahn, M.; Hu, S.L.; Lee, K.K. J Virol 87, 10855-73 (2013).
-
Neurofilament sidearms modulate parallel and crossed-filament orientations inducing nematic to isotropic and re-entrant birefringent hydrogels.
Deek, J.; Chung, P.J.; Kayser, J.; Bausch, A.R.; Safinya, C.R. Nat Commun 4, 2224 (2013).
-
Virus assembly and maturation: auto-regulation through allosteric molecular switches.
Domitrovic, T.; Movahed, N.; Bothner, B.; Matsui, T.; Wang, Q.; Doerschuk, P.C.; Johnson, J.E. J Mol Biol 425, 1488-96 (2013).
-
Molecular model of a soluble guanylyl cyclase fragment determined by small-angle X-ray scattering and chemical cross-linking.
Fritz, B.G.; Roberts, S.A.; Ahmed, A.; Breci, L.; Li, W.; Weichsel, A.; Brailey, J.L.; Wysocki, V.H.; Tama, F.; Montfort, W.R. Biochemistry 52, 1568-82 (2013).
-
The structure of yeast glutaminyl-tRNA synthetase and modeling of its interaction with tRNA.
Grant, T.D.; Luft, J.R.; Wolfley, J.R.; Snell, M.E.; Tsuruta, H.; Corretore, S.; Quartley, E.; Phizicky, E.M.; Grayhack, E.J.; Snell, E.H. J Mol Biol 425, 2480-93 (2013).
-
All-atom ensemble modeling to analyze small-angle x-ray scattering of glycosylated proteins.
Guttman, M.; Weinkam, P.; Sali, A.; Lee, K.K. Structure 21, 321-31 (2013).
-
A functional interaction between gp41 and gp120 is observed for monomeric but not oligomeric, uncleaved HIV-1 Env gp140.
Guttman, M.; Lee, K.K. J Virol 87, 11462-75 (2013).
-
αE-catenin actin-binding domain alters actin filament conformation and regulates binding of nucleation and disassembly factors.
Hansen, S.D.; Kwiatkowski, A.V.; Ouyang, C.Y.; Liu, H.; Pokutta, S.; Watkins, S.C.; Volkmann, N.; Hanein, D.; Weis, W.I.; Mullins, D.; Nelson, J. Mol Biol Cell 24, 3710-20 (2013).
-
Structure of the arginine methyltransferase PRMT5-MEP50 reveals a mechanism for substrate specificity.
Ho, M.C.; Wilczek, C.; Bonanno, J.B.; Xing, L.; Seznec, J.; Matsui, T.; Carter, L.G.; Onikubo, T.; Kumar, R.; Chan, M.K.; Brenowitz, M.; Cheng, H.; Reimer, U.; Almo, S.C.; Shechter, D. PLoS One 8, e57008 (2013).
-
A critical evaluation of random copolymer mimesis of homogeneous antimicrobial peptides.
Hu, K.; Schmidt, N.W.; Zhu, R.; Jiang, Y.; Lai, G.Hwee; Wei, G.; Palermo, E.F.; Kuroda, K.; Wong, G.C.L.; Yang, L. Macromolecules 46, 1908-1915 (2013).
-
Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9.
Julien, J.P.; Lee, J.Hyun; Cupo, A.; Murin, C.D.; Derking, R.; Hoffenberg, S.; Caulfield, M.J.; King, R.; Marozsan, A.J.; Klasse, P.Johan; Sanders, R.W.; Moore, J.P.; Wilson, I.A.; Ward, A.B. Proc Natl Acad Sci U S A 110, 4351-6 (2013).
-
A common structure for the potexviruses.
Kendall, A.; Bian, W.; Maris, A.; Azzo, C.; Groom, J.; Williams, D.; Shi, J.; Stewart, P.L.; Wall, J.S.; Stubbs, G. Virology 436, 173-8 (2013).
-
Barley stripe mosaic virus: structure and relationship to the tobamoviruses.
Kendall, A.; Williams, D.; Bian, W.; Stewart, P.L.; Stubbs, G. Virology 443, 265-70 (2013).
-
Stacking of Short DNA Induces the Gyroid Cubic-to-Inverted Hexagonal Phase Transition in Lipid-DNA Complexes.
Leal, C.; Ewert, K.K.; Bouxsein, N.F.; Shirazi, R.S.; Li, Y.; Safinya, C.R. Soft Matter 9, 795-804 (2013).
-
Hexamers of the type II secretion ATPase GspE from Vibrio cholerae with increased ATPase activity.
Lu, C.; Turley, S.; Marionni, S.T.; Park, Y.J.; Lee, K.K.; Patrick, M.; Shah, R.; Sandkvist, M.; Bush, M.F.; Hol, W.G.J. Structure 21, 1707-17 (2013).
-
Structural study of hNck2 SH3 domain protein in solution by circular dichroism and X-ray solution scattering.
Matsumura, Y.; Shinjo, M.; Matsui, T.; Ichimura, K.; Song, J.; Kihara, H. Biophys Chem 175-176, 39-46 (2013).
-
Danio rerio αE-catenin is a monomeric F-actin binding protein with distinct properties from Mus musculus αE-catenin.
Miller, P.W.; Pokutta, S.; Ghosh, A.; Almo, S.C.; Weis, W.I.; Nelson, J.; Kwiatkowski, A.V. J Biol Chem 288, 22324-32 (2013).
-
Ion specific effects in bundling and depolymerization of taxol-stabilized microtubules.
Needleman, D.J.; Ojeda-Lopez, M.A.; Raviv, U.; Miller, H.P.; Li, Y.; Song, C.; Feinstein, S.C.; Wilson, L.; Choi, M.Chul; Safinya, C.R. Faraday Discuss 166, 31-45 (2013).
-
Conformational analysis of StrH, the surface-attached exo-β-D-N-acetylglucosaminidase from Streptococcus pneumoniae.
Pluvinage, B.; Chitayat, S.; Ficko-Blean, E.; Abbott, W.; Kunjachen, J.Maroor; Grondin, J.; Spencer, H.L.; Smith, S.P.; Boraston, A.B. J Mol Biol 425, 334-49 (2013).
-
Structure, dynamics, evolution, and function of a major scaffold component in the nuclear pore complex.
Sampathkumar, P.; Kim, S.Joong; Upla, P.; Rice, W.J.; Phillips, J.; Timney, B.L.; Pieper, U.; Bonanno, J.B.; Fernandez-Martinez, J.; Hakhverdyan, Z.; Ketaren, N.E.; Matsui, T.; Weiss, T.M.; Stokes, D.L.; Sauder, M.; Burley, S.K.; Sali, A.; Rout, M.P.; Almo, S.C. Structure 21, 560-71 (2013).
-
Influenza virus A M2 protein generates negative Gaussian membrane curvature necessary for budding and scission.
Schmidt, N.W.; Mishra, A.; Wang, J.; Degrado, W.F.; Wong, G.C.L. J Am Chem Soc 135, 13710-9 (2013).
-
Structural ensemble and microscopic elasticity of freely diffusing DNA by direct measurement of fluctuations.
Shi, X.; Herschlag, D.; Harbury, P.A.B. Proc Natl Acad Sci U S A 110, E1444-51 (2013).
-
Purification and SAXS analysis of the integrin linked kinase, PINCH, parvin (IPP) heterotrimeric complex.
Stiegler, A.L.; Grant, T.D.; Luft, J.R.; Calderwood, D.A.; Snell, E.H.; Boggon, T.J. PLoS One 8, e55591 (2013).
-
Nucleotide and partner-protein control of bacterial replicative helicase structure and function.
Strycharska, M.S.; Arias-Palomo, E.; Lyubimov, A.Y.; Erzberger, J.P.; O'Shea, V.L.; Bustamante, C.J.; Berger, J.M. Mol Cell 52, 844-54 (2013).
-
Structure of the Streptococcus pneumoniae surface protein and adhesin PfbA.
Suits, M.D.; Boraston, A.B. PLoS One 8, e67190 (2013).
-
Heterogeneous seeding of a prion structure by a generic amyloid form of the fungal prion-forming domain HET-s(218-289).
Wan, W.; Bian, W.; McDonald, M.; Kijac, A.; Wemmer, D.E.; Stubbs, G. J Biol Chem 288, 29604-12 (2013).
-
Scalable and selective dispersion of semiconducting arc-discharged carbon nanotubes by dithiafulvalene/thiophene copolymers for thin film transistors.
Wang, H.; Mei, J.; Liu, P.; Schmidt, K.; Jiménez-Osés, G.; Osuna, S.; Fang, L.; Tassone, C.J.; Zoombelt, A.Pieter; Sokolov, A.N.; Houk, K.N.; Toney, M.F.; Bao, Z. ACS Nano 7, 2659-68 (2013).
-
Dynamics in cryo EM reconstructions visualized with maximum-likelihood derived variance maps.
Wang, Q.; Matsui, T.; Domitrovic, T.; Zheng, Y.; Doerschuk, P.C.; Johnson, J.E. J Struct Biol 181, 195-206 (2013).
-
Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12.
Wu, Y.; West, A.P.; Kim, H.J.; Thornton, M.E.; Ward, A.B.; Bjorkman, P.J. Cell Rep 5, 1443-55 (2013).