Overview
Macromolecular Crystallography, 8-pole Wiggler Side Station
Beam line 7-1 is a 8-pole, 2.0-Tesla wiggler side-station beam line optimized for monochromatic, high-throughput, high-resolution macromolecular crystallography. It is SAD and MAD capable and can be run in a full remote access mode. It is equipped with an ADSC Q315R CCD detector. Currenlty 7-1 is dedicated to staff development and user training.
See the Macromolecular Crystallography website for details.
Sample Environment —
| Standard | Ambient pressure |
|---|---|
| Sample temperature: 100K - room temperature |
Instrumentation —
| Detectors | ADSC Quantum 315r CCD, sample to detector distance of 110-650 mm; maximum vertical offset: 75 mm |
|---|---|
| Goniometer | Huber Kappa-geometry goniometer |
| Cryo Capability | Oxford Cryojet |
Publications
Publications
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Highlights
Science Highlights
Beam Line 7-1 Science Highlights
First Atomic Structure of an Intact Polyketide Synthase Revealing Two Asynchronous Reaction Chambers
Shedding Light on Photoisomerization: Electrostatic Control of Excited State Reaction Pathways within Proteins
Structure of the Human Cysteine Desulfurase Complex
Structure of Chinese Herbal-based Medicine Captured by ATP on a Human tRNA Synthetase
Crystal Structure and Functional Analysis Identify Evolutionary Secret of SerRS in Vascular Development
High Resolution Structure of the Neisseria gonorrhoeae Type IV Pilus: A Membrane-bound Fibrous Assembly
Small-Molecule Inhibition of TNF-alpha
Side-on Cu-Nitrosyl Coordination by Nitrite Reductase
Crystal Structures of Anthrax Toxin Lethal Factor Bound to an Optimized Substrate and Candidate Small Molecule Inhibitors
Crystal Structures of Mammalian Carboxylesterases and Their Function in Drug and Xenobiotic Metabolism
Cooperation of Rab and Arl GTPase Family Members in Localization of the Golgin GCC185
Structural Studies of Nitric Oxide Synthase Inhibitor Complexes: An Anchored Plasticity Approach for Selective Enzyme Inhibition
Crystal Structure of the Hexameric Assembly Unit of the HIV Capsid
Marine Diatoms Survive Iron Droughts in the Ocean by Storing Iron in Ferritin
Structure of an Unusually Small RNA Switch Provides Insight into the Minimal Requirements for Microbial Gene Regulation
Metal templated protein interface design
Controlling Protein Aggregation: Lessons from Fungi
Structure of an Enzyme Catalyzing an Unfavorable Ring Closure Revealed
Towards Understanding Anthrax: Structural Basis of Target Recognition by Anthrax Lethal Factor
Experimental Station 7-1
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