BL4-2 Biological Small Angle Scattering/Diffraction

Results of Users' Research

1. SSRL Highlight Articles

2. Publications from BL 4-2 at SSRL

This is a partial list of publications based on B-SAXS/D experiments on BL 4-2 at SSRL.  We encourage you to let us know of any omissions.

2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1996 1995 1994 1993


Y. Liang, M. Guttman, J. A. Williams, H. Verkerke, D. Alvarado, S.-L. Hu and K. K. Lee, "Changes in Structure and Antigenicity in HIV-1 Env Trimers Resulting from Removal of a Conserved CD4 Binding Site-proximal Glycan", J. Virol. (2016), doi: 10.1128/JVI.01116-16

M. G. Joyce, B. Zhang, L. Ou, M. Chen, G.-Y. Chuang, A. Druz, W.-P. Kong, Y.-T. Lai, E. J. Rundlet, Y. Tsybovsky, Y. Yang, I. S. Georgiev, M. Guttman, C. R. Lees, M. Pancera, M. Sastry, C. Soto, G. B. E. Stewart-Jones, P. V. Thomas, J. G. Van Galen, U. Baxa, K. K. Lee, J. R. Mascola, B. S. Graham and P. D. Kwong, "Iterative Structure-based Improvement of a Fusion-glycoprotein Vaccine against RSV", Nat. Struct. Mol. Biol. (2016), doi: 10.1038/nsmb.3267

X. Shi, L. Huang, D. M. Lilley, P. B. Harbury and D. Herschlag, "The Solution Structural Ensembles of RNA Kink-turn Motifs and Their Protein Complexes", Nat. Chem. Biol. 12, 146 (2016), doi: 10.1038/nchembio.1997

W. R. Hollingsworth, C. Segura, J. Balderrama, N. Lopez, P. Schleissner and A. L. Ayzner, "Exciton Transfer and Emergent Excitonic States in Oppositely- charged Conjugated Polyelectrolyte Complexes", J. Phys. Chem. B (2016), doi: 10.1021/acs.jpcb.6b065

S. Rahighi, I. Braunstein, N. Ternette, B. Kessler, M. Kawasaki, R. Kato, T. Matsui, T. M. Weiss, A. Stanhill and S. Wakatsuki, "Selective Binding of AIRAPL Tandem UIMs to Lys48-linked Tri-ubiquitin Chains", Structure 24, 412 (2016), doi: 10.1016/j.str.2015.12.017

I. C. Tran, R. H. Tunuguntla, K. Kim, J. R. I. Lee, T. M. Willey, T. M. Weiss, A. Noy and T. van Buuren, "Structure of Carbon Nanotube Porins in Lipid Bilayers: An in Situ Small-Angle X-ray Scattering (SAXS) Study", Nano Lett. 16, 4019 (2016), doi: 10.1021/acs.nanolett.6b00466

K. Engberg, D. A. Waters, S. Kelmanovich, R. Parke-Houben, L. Hartmann, M. F. Toney and C. W. Frank, "Self-assembly of Cholesterol Tethered within Hydrogel Networks", Polymer 84, 371 (2016), doi: 10.1016/j.polymer.2016.01.015

M. A. Al-Dulaymi, J. M. Chitanda, W. Mohammed-Saeid, H. Y. Araghi, R. E. Verrall, P. Grochulski and I. Badea, "Di-Peptide-Modified Gemini Surfactants as Gene Delivery Vectors: Exploring the Role of the Alkyl Tail in Their Physicochemical Behavior and Biological Activity", AAPS J (2016), doi: 10.1208/s12248-016-9906-1

J. Deek, P. J. Chung and C. R. Safinya, "Neurofilament Networks: Salt-responsive Hydrogels with Sidearm-dependent Phase Behavior", Biochim. Biophys. Acta 1860, 1560 (2016), doi: 10.1016/j.bbagen.2016.03.018

F. Tondnevis, T. M. Weiss, T. Matsui, L. B. Bloom and R. McKenna, "Solution Structure of an "Open" E. coli Pol III Clamp Loader Sliding Clamp Complex", J. Struct. Biol. 194, 272 (2016), doi: 10.1016/j.jsb.2016.03.003

S. Sankhagowit, E. Y. Lee, G. C.-L. Wong and N. Malmstadt, "Oxidation of Membrane Curvature-regulating Phosphatidylethanolamine Lipid Results in Formation of Bilayer and Cubic Structures", Langmuir 32, 2450 (2016), doi: 10.1021/acs.langmuir.5b04332

Y. Liang, M. Guttman, T. M. Davenport, S.-L. Hu and K. K. Lee, "Probing the Impact of Local Structural Dynamics of Conformational Epitopes on Antibody Recognition", Biochemistry 55, 2197 (2016), doi: 10.1021/acs.biochem.5b01354

P. J. Chung, C. Song, J. Deek, H. P. Miller, Y. Li, M. C. Choi, L. Wilson, S. C. Feinstein and C. R. Safinya, "Tau Mediates Microtubule Bundle Architectures Mimicking Fascicles of Microtubules Found in the Axon Initial Segment", Nat. Commun. 7, 12278 (2016), doi: 10.1038/ncomms12278

M. D. Tuttle, G. Comellas, A. J. Nieuwkoop, D. J. Covell, D. A. Bethold, K. D. Kloepper, J. M. Courtney, J. K. Kim, A. M. Barclay, A. Kendall, W. Wan, G. Stubbs, C. D. Schwieters, V. M.-Y. Lee, J. M. George and C. M. Rienstra, "Solid-state NMR Structure of a Pathogenic Fibril of Full-length Human alpha-synuclein", Nat. Struct. Mol. Biol. 23, 409 (2016), doi: 10.1038/nsmb.3194

C. R. Safinya, P. J. Chung, C. Song, Y. Li, K. K. Ewert and M. C. Choi, "The Effect of Multivalent Cations and Tau on Paclitaxel-stabilized Microtubule Assembly, Disassembly, and Structure", Adv. Colloid. Interfac. 232, 9 (2016), doi: 10.1016/j.cis.2015.11.002

R. P. Barnwal, E. Loh, K. S. Godin, J. Yip, H. Lavender, C. M. Tang and G. Varani, "Structure and Mechanism of a Molecular Rheostat, an RNA Thermometer that Modulates Immune Evasion by Neisseria meningitidis", Nucleic Acids Res. (2016), doi: 10.1093/nar/gkw584

R. C. Huber, A. S. Ferreira, J. C. Aguirre, D. Kilbride, D. B. Toso, K. Mayoral, Z. H. Zhou, N. Kopidakis, Y. Rubin, B. J. Schwartz, T. G. Mason and S. H. Tolbert, "Structure and Conductivity of Semiconducting Polymer Hydrogels", J. Phys. Chem. B 120, 6215 (2016), doi: 10.1021/acs.jpcb.6b0220

H. Zhao, J. A. Speir, T. Matsui, Z. Lin, L. Liang, A. Y. Lynn, B. Varnado, T. M. Weiss and L. Tang, "Structure of a Bacterial Virus DNA-injection Protein Complex Reveals a Decameric Assembly with a Constricted Molecular Channel", PLoS One 11, e0149337 (2016), doi: 10.1371/journal.pone.0149337

Y.-L. Rao, A. Chortos, R. Pfattner, F. Lissel, Y.-C. Chiu, V. Feig, J. Xu, T. Kurosawa, X. Gu, C. Wang, M. He, J. W. Chung and Z. Bao, "Stretchable Self-Healing Polymeric Dielectrics Cross-linked through Metal–ligand Coordination", J. Am. Chem. Soc. 138, 6020 (2016), doi: 10.1021/jacs.6b02428

H. Kang, T. M. Weiss, I. Bang, W. I. Weis and H.-J. Choi, "Structure of the Intermediate Filament-binding Region of Desmoplakin", PLoS One 11, e0147641 (2016), doi: 10.1371/journal.pone.0147641

I. Lucic, L. Truebestein and T. A. Leonard, "Novel Features of DAG-activated PKC Isozymes Reveal a Conserved 3-D Architecture", J. Mol. Biol. 428, 121 (2016), doi: 10.1016/j.jmb.2015.11.001

E. Y. Lee, C. K. Lee, N. W. Schmidt, F. Jin, R. Lande, T. Curk, D. Frenkel, J. Dobnikar, M. Gilliet and G. C.-L. Wong, "A Review of Immune Amplification via Ligand Clustering by Self-assembled Liquid-crystalline DNA Complexes", Adv. Colloid. Interfac. 232, 17 (2016), doi: 10.1016/j.cis.2016.02.003

P. J. Chung and C. R. Safinya, "Probing Forces Generated and Architectures Mediated by Tau on Microtubules", University of California (Santa Barbara), 2016

S. Wang, C. Ing, S. Emami, Y. Jiang, H. Liang, R. Pomes, L. S. Brown and V. Ladizhansky, "Structure and Dynamics of Extracellular Loops in Human Aquaporin-1 from Solid-state NMR and Molecular Dynamics", J. Phys. Chem. B 120, 9887 (2016), doi: 10.1021/acs.jpcb.6b06731

L. Sun, Y. Song, D. Blocquel, X.-L. Yang and P. Schimmel, "Two Crystal Structures Reveal Design for Repurposing the C-Ala Domain of Human AlaRS", Proc. Natl. Acad. Sci. USA 113, 14300 (2016), doi: 10.1073/pnas.1617316113

B. L. Timney, B. Ravneh, R. Mironska, J. M. Trivedi, S. J. Kim, D. Russel, S. R. Wente, A. Sali and M. P. Rout, "Simple Rules for Passive Diffusion through the Nuclear Pore Complex", J. Cell Biol. 215, 57 (2016), doi: 10.1083/jcb.201601004

E. Y. Lee, B. M. Fulan, G. C. L. Wong and A. L. Ferguson, "Mapping Membrane Activity in Undiscovered Peptide Sequence Space Using Machine Learning", Proc. Natl. Acad. Sci. USA 113, 13588 (2016), doi: 10.1073/pnas.1609893113


A. Criswell, B. H. M. Mooers and F. J. Schmidt, "Structural Studies of a Double-stranded RNA from Trypanosome RNA Editing by Small-angle X-ray Scattering", in RNA-RNA Interactions: Methods in Molecular Biology, Springer (2015)

J. Yin, A. J. Schoeffler, K. Wickliffe, K. Newton, M. A. Starovasnik, E. C. Dueber and S. F. Harris, "Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46", Structure 23, 2043 (2015), doi: 10.1016/j.str.2015.08.010

L. Carter, S. J. Kim, D. Schneidman-Duhovny, J. Stohr, G. Poncet-Montange, T. M. Weiss, H. Tsuruta, S. B. Prusiner and A. Sali, "Prion Protein--Antibody Complexes Characterized by Chromatography-coupled Small-angle X-ray Scattering", Biophys. J. 109, 793 (2015), doi: 10.1016/j.bpj.2015.06.065

C. Chen, C. Huang, I. Waluyo, T. Weiss, L. G.-M. Pettersson and A. Nilsson, "Long-range Ion-Water and Ion-Ion Interactions in Aqueous Solutions", Phys. Chem. Chem. Phys. 17, 8427 (2015), doi: 10.1039/C4CP04759A

W. G. Saw, G. Tria, A. Gruber, M. S. Supamanian Manimekalai, Y. Zhao, A. Chandramohan, G. Srinivasan Anand, T. Matsui, T. M. Weiss, S. G. Vasudevan and G. Gruber, "Structural Insight and Flexible Features of NS5 Proteins from all Four Serotypes of Dengue Virus in Solution", Acta Crystallogr. D 71, 2309 (2015), doi: 10.1107/S1399004715017721

S. Gupta, M. Guttman, R. L. Leverenz, K. Zhumadilova, E. G. Pawlowski, C. J. Petzold, K. K. Lee, C. Y. Ralston and C. A. Kerfeld, "Local and Global Structural Drivers for the Photoactivation of the Orange Carotenoid Protein", Proc. Natl. Acad. Sci. USA 112, E5567 (2015) doi: 10.1073/pnas.1512240112

P. J. Chung, M. C. Choi, H. P. Miller, H. E. Feinstein, U. Raviv, Y. Li, L. Wilson, S. C. Feinstein and C. R. Safinya, "Direct Force Measurements Reveal that Protein Tau Confers Short-range Attractions and Isoform-dependent Steric Stabilization to Microtubules", Proc. Natl. Acad. Sci. USA 112, E6416 (2015), doi: 10.1073/pnas.1513172112

G. G. Harris, P. M. Lombardi, T. A. Pemberton, T. Matsui, T. M. Weiss, K. E. Cole, M. Koksal, F. V. Murphy, L. S. Vedula, W. K.-W. Chou, D. E. Cane and D. W. Christianson, "Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with aa Domain Architecture that Catalyzes a Unique Cyclization-Fragmentation Reaction Sequence", Biochemistry 54, 7142 (2015), doi: 10.1021/acs.biochem.5b01143

J. LoPiccolo, S. J. Kim, Y. Shi, B. Wu, H. Wu, B. T. Chait, R. H. Singer, A. Sali, M. penowitz, A. R. pesnick and J. M. Backer, "Assembly and Molecular Architecture of the Phosphoinositide 3-Kinase p85alpha Homodimer", J. Biol. Chem. 290, 30390 (2015), doi: 10.1074/jbc.M115.689604

C. Dong, I. Badea, M. Poorghorban, R. Verrall and M. Foldvari, "Impact of Phospholipids on Plasmid Packaging and Toxicity of Gemini Nanoparticles", J. Mater. Chem. B 3, 8806 (2015), doi: 10.1039/C5TB01400J

W.-C. Lee, W.-L. Lin, T. Matsui, E. S.-W. Chen, T.-Y. W. Wei, W.-H. Lin, H. Hu, Y. G. Zheng, M.-D. Tsai and M.-C. Ho, "Protein Arginine Methyltransferase 8: Tetrameric Structure and Protein Substrate Specificity", Biochemistry 54, 7514 (2015), doi: 10.1021/acs.biochem.5b00995

J. A. Latham, A. T. Iavarone, I. Barr, P. V. Juthani and J. P. Klinman, "PqqD is a Novel Peptide Chaperone that Forms a Ternary Complex with the Radical S-Adenosylmethionine Protein PqqE in the Pyrroloquinoline Quinone Biosynthetic Pathway", J. Biol. Chem. 290, 129089 (2015), doi: 10.1074/jbc.M115.646521

W. Wan, H. Wille, J. Stohr, A. Kendall, W. Bian, M. McDonald, S. Tiggelaar, J. C. Watts, S. B. Prusiner and G. Stubbs, "Structural Studies of Truncated Forms of the Prion Protein PrP", Biophys. J. 108, 1548 (2015), doi: 10.1016/j.bpj.2015.01.008

J. J. Amaral, J. Wan, A. L. Rodarte, C. Ferri, M. T. Quint, R. J. Pandolfi, M. Scheibner, L. S. Hirst and S. Ghosh, "Magnetic Field Induced Quantum Dot Brightening in Liquid Crystal Synergized Magnetic and Semiconducting Nanoparticle Composite Assemblies", Soft Matter 11, 255 (2015), doi: 10.1039/C4SM02015D

B. B. Silva, M. Zepeda-Rosales, N. Venkateswaran, B. J. Fletcher, L. G. Carter, T. Matsui, T. M. Weiss, J. Han, Y. Li, U. Olsson and C. R. Safinya, "Nematic Director Reorientation at Solid and Liquid Interfaces under Flow: SAXS Studies in a Microfluidic Device", Langmuir 3 , 4361 (2015), doi: 10.1021/la5034614

D. C.-F. Monteiro, V. Patel, C. P. Bartlett, S. Nozaki, T. D. Grant, J. A. Gowdy, G. S. Thompson, A. P. Kalverda, E. H. Snell, H. Niki, A. R. Pearson and M. E. Webb, "The Structure of the PanD/PanZ Protein Complex Reveals Negative Feedback Regulation of Pantothenate Biosynthesis by Coenzyme A", Chem. Biol. 22, 492 (2015), doi: 10.1016/j.chembiol.2015.03.017

J. R. Kramer, N. W. Schmidt, K. M. Mayle, D. T. Kamei, G. C.-L. Wong and T. J. Deming, "Reinventing Cell Penetrating Peptides Using Glycosylated Methionine Sulfonium Ion Sequences", ACS Cent. Sci. 1, 83 (2015), doi: 10.1021/acscentsci.5b00054

J. R.-I. Lee, M. Bagge-Hansen, R. Tunuguntla, K. Kim, M. Bangar, T. M. Willey, I. C. Tran, D. A. Kilcoyne, A. Noy and T. van Buuren, "Ordering in Bio-inorganic Hybrid Nanomaterials Probed by In Situ Scanning Transmission X-ray Microscopy", Nanoscale 7, 9477 (2015), doi: 10.1039/C5NR00622H

M. E. Ward, S. Wang, R. Munro, E. Ritz, I. Hung, P. L. Gor'kov, Y. Jiang, H. Liang, L. S. Brown and V. Ladizhansky, "In situ Structural Studies of Anabaena Sensory Rhodopsin in the E. coli Membrane", Biophys. J. 108, 1683 (2015), doi: 10.1016/j.bpj.2015.02.018

X. Shi, S. Bonilla, D. Herschlag and P. Harbury, "Quantifying Nucleic Acid Ensembles with X-ray Scattering Interferometry", Methods Enzymol. 558, 75 (2015), doi: 10.1016/bs.mie.2015.02.001

V. Vittal, L. Shi, D. M. Wenzel, K. M. Scaglione, E. D. Duncan, V. Basrur, K. S.-J. Elenitoba-Johnson, D. Baker, H. L. Paulson, P. S. Brozovic and R. E. Klevit, "Intrinsic Disorder Drives N-Terminal Ubiquitination by Ube2w", Nat. Chem. Biol. 11, 83 (2015), doi: 10.1038/nchembio.1700

N. K. Garcia, M. Guttman, J. L. Ebner and K. K. Lee, "Dynamic Changes during Acid-induced Activation of Influenza Hemagglutinin", Structure 23, 665 (2015), doi: 10.1016/j.str.2015.02.006

T. D. Grant, J. R. Luft, L. G. Carter, T. Matsui, T. M. Weiss, A. Martel and E. H. Snell, "The Accurate Assessment of Small-angle X-ray Scattering Data", Acta Crystallogr. D 71, 45 (2015), doi: 10.1107/S1399004714010876

G. E. Owens, D. M. New, A. P. West and P. J. Bjorkman, "Anti-PolyQ Antibodies Recognize a Short PolyQ Stretch in Both Normal and Mutant Huntingtin Exon 1", J. Mol. Biol. 42 , 2507 (2015), doi: 10.1016/j.jmb.2015.05.023

N. W. Schmidt, F. Jin, R. Lande, T. Curk, W. Xian, C. Lee, L. Frasca, D. Frenkel, J. Dobnikar, M. Gilliet and G. C.-L. Wong, "Liquid-Crystalline Ordering of Antimicrobial Peptide-DNA Complexes Controls TLR9 Activation", Nat. Mater. 14, 696 (2015), doi: 10.1038/nmat4298

K. Hu, Y. Jiang, Y. Xie, H. Liu, R. Liu, Z. Zhao, R. Lai and L. Yang, "Small-Anion Selective Transmembrane "Holes" Induced by an Antimicrobial Peptide Too Short to Span Membranes", J. Phys. Chem. B 119, 8553 (2015), doi: 10.1021/acs.jpcb.5b03133

M. Poorghorban, U. Das, O. Alaidi, J. M. Chitanda, D. Michel, J. Dimmock, R. Verrall, P. Grochulski and I. Badea, "Characterization of the Host-Guest Complex of a Curcumin Analog with beta-Cyclodextrin and beta-Cyclodextrin-gemini Surfactant and Evaluation of Its Anticancer Activity", Int. J. Nanomed. 10, 503 (2015), doi: 10.2147/IJN.S70828

A. C. Fyfe, P. W. Dunten, M. M. Martick and W. G. Scott, "Structural Variations and Solvent Structure of r(UGGGGU) Quadruplexes Stabilized by Sr2+ Ions", J. Mol. Biol. 427, 2205 (2015), doi: 10.1016/j.jmb.2015.03.022

A. L. Rodarte, B. H. Cao, H. Panesar, R. J. Pandolfi, M. Quint, L. Edwards, S. Ghosh, J. E. Hein and L. S. Hirst, "Self-assembled Nanoparticle Micro-shells Templated by Liquid Crystal Sorting", Soft Matter 11, 1701 (2015), doi: 10.1039/C4SM02326A

E. A. Sweeny, M. E. Jackrel, M. S. Go, M. A. Sochor, B. M. Razzo, M. E. DeSantis, K. Gupta and J. Shorter, "The Hsp104 N-Terminal Domain Enables Disaggregase Plasticity and Potentiation", Mol. Cell 57, 836 (2015), doi: 10.1016/j.molcel.2014.12.021

R. C. Huber, A. S. Ferreira, R. Thompson, D. Kilbride, N. S. Knutson, L. S. Devi, D. B. Toso, J. R. Challa, Z. H. Zhou, Y. Rubin, B. J. Schwartz and S. H. Tolbert, "Long-lived Photoinduced Polaron Formation in Conjugated Polyelectrolyte-fullerene Assemblies", Science 348, 1340 (2015), doi: 10.1126/science.aaa6850

C. R. Safinya, J. Deek, R. Beck, J. B. Jones and Y. Li, "Assembly of Biological Nanostructures: Isotropic and Liquid Crystalline Phases of Neurofilament Hydrogels", Ann. Rev. Cond. Mat. Phys. 6, 113 (2015), doi: 10.1146/annurev-conmatphys-031214-014623

C. Lor and L. S. Hirst, "Effects of Low Concentrations of Docosahexaenoic Acid on the Structure and Phase Behavior of Model Lipid Membranes", Membranes 5, 857 (2015), doi: 10.3390/membranes5040857

A. Mendes, M. Vlok, J. R. Short, T. Matsui and R. A. Dorrington, "An Encapsidated Viral Protein and Its Role in RNA Packaging by a Non-enveloped Animal RNA Virus", Virology 476, 323 (2015), doi: 10.1016/j.virol.2014.12.026

C. Liu, "Design, Synthesis and Evaluation of Bivalent Inhibitors of Trehalose-6-phosphate Phosphatase", University of New Mexico, 2015; Advisor: D. Dunaway-Mariano

F. Tondnevis, "Structural, Biophysical and Biochemical Studies of Replication Proteins", University of Florida, 2015; Advisors: L. Bloom and R. McKenna

A. S. Ferreira, "Using Self-assembly to Control Nanoscale Morphology in Semiconducting Polymers for Application in Organic Photovoltaics", University of California (Los Angeles), 2015; Advisor: S. H. Tolbert

N. K. Garcia, "Decoding the Structural Determinants of Hemagglutinin Mediated Influenza Entry and Antigenicity", University of Washington, 2015; Advisor: K. K. Lee

J. R. Kane, "Lineage-specific Hijacking of Non-canonical Cofactors in the Evolution of Lentiviral Vif Anti-APOBEC3 Activity", University of California (San Francisco), 2015; Advisor: N. J. Krogan

R. L. Roberts, M.Sc. thesis, "Structural and Bioinformatic Analysis of Ethylmalonyl-CoA Decarboxylase", State University of New York (Buffalo), 2015; Advisor: E. H. Snell

C. Lor, "Phase Behavior and Nanotube Formation in Lipid Membranes", University of California (Merced), 2015; Advisor: L. S. Hirst

M. O. Sheikh, "Control of the Oxygen Sensing in Dictyostelium by Glycosylationdependent Changes in Skp1 Protein Conformation and E3(SCF)ubiquitin Ligase Assembly", University of Oklahoma, 2015; Advisor: C. M. West

V. Vittal, "Structural and Functional Characterization of Non-Canonical Ubiquitin Conjugating Enzymes", University of Washington, 2015; Advisor: R. E. Klevit

Y. Jiang, M.Sc. thesis, "Hydrophilic and Cationic Polymers as Potent Antimicrobial Materials: Another Pathway to Fight Tough Bacterial Infections", Colorado School of Mines, 2015; Advisor: H. Liang


M. Guttman, N. K. Garcia, A. Cupo, T. Matsui, J.-P. Julien, R. W. Sanders, I. A. Wilson, J. Moore and K. K. Lee, "CD4-Induced Activation in a Soluble HIV-1 Env Trimer", Structure 22, 974 (2014), doi: 10.1016/j.str.2014.05.001

T. Matsui, S. Gu, K.-h. Lam, L. G. Carter, A. Rummel, I. I. Mathews and R. Jin, "Structural Basis of the pH-dependent Assembly of Botulinum Neurotoxin Complex", J. Mol. Biol. 426, 3773 (2014), doi: 10.1016/j.jmb.2014.09.009

B. F.-B. Silva, R. N. Majzoub, C.-L. Chan, Y. Li, U. Olsson and C. R. Safinya, "PEGylated Cationic Liposome-DNA Complexation in Brine is Pathway-Dependent", Biochim. Biophys. Acta 1838, 398 (2014), doi: 10.1016/j.bbamem.2013.09.008

J. V. Chodaparambil, K. T. Pate, M. R.-D. Hepler, B. P. Tsai, U. M. Muthurajan, K. Luger, M. L. Waterman and W. I. Weis, "Molecular Functions of the TLE Tetramerization Domain in Wnt Target Gene Repression", EMBO J. 33, 719 (2014), doi: 10.1002/embj.201387188

J. A. Bartelt, J. D. Douglas, W. R. Matekar, A. El Labban, C. J. Tassone, M. F. Toney, J. M.-J. Frechet, P. M. Beaujuge and M. D. McGehee, "Controlling Solution-Phase Polymer Aggregation with Molecular Weight and Solvent Additives to Optimize Polymer-Fullerene Bulk Heterojunction Solar Cells", Adv. Eng. Mater. 4, 1301733 (2014), doi: 10.1002/aenm.201301733

X. Shi, K. Beauchamp, P. A.-B. Harbury and D. Herschlag, "From a Structural Average to the Conformational Ensemble of a DNA Bulge", Proc. Natl. Acad. Sci. USA 111, E1473 (2014), doi: 10.1073/pnas.1317032111

W. Wan and G. Stubbs, "Heterogeneous Seeding of HET-s(218-289) and the Mutability of Prion Structures", Prion 8 (2014), doi: 10.1074/jbc.M113.505511

M. W. Lee, S. Chakraborty, N. W. Schmidt, R. Murgai, S. H. Gellman and G. C.-L. Wong, "Two Interdependent Mechanisms of Antimicrobial Activity Allow for Efficient Killing in Nylong-3-based Polymeric Mimics of Innate Immunity Peptides", Biochim. Biophys. Acta 1838, 2269 (2014), doi: 10.1016/j.bbamem.2014.04

L. Kuang, D. A. Fernandes, M. O'Halloran, W. Zheng, Y. Jiang, V. Ladizhansky, L. S. Brown and H. Liang, "'Frozen' Block Copolymer Nanomembranes with Light-Driven Proton Pumping Performance", ACS Nano 8, 537 (2014), doi: 10.1021/nn4059852

C. R. Safinya, K. K. Ewert, R. N. Majzoub and C. Leal, "Cationic Liposome-Nucleic Acie Complexes for Gene Delivery and Gene Silencing", New J. Chem. 38, 5164 (2014), doi: 10.1039/C4NJ01314J

B. Trastoy, J. V. Lomino, B. G. Pierce, L. G. Carter, S. Gunther, J. P. Giddens, G. A. Snyder, T. M. Weiss, Z. Weng, L.-X. Wang and E. J. Sundberg, "Crystal Structure of Streptococcus pyogenes EndoS, an Immunomodulatory Endoglycosidase Specific for Human IgG Antibodies", Proc. Natl. Acad. Sci. USA 111, 6704 (2014), doi: 10.1073/pnas.1322908111

K. H. Piepenbrink, G. A. Maldarelli, C. F. Martinez de la Pena, G. L. Mulvey, G. A. Snyder, L. De Masi, E. C. von Rosenvinge, S. Guenther, G. D. Armstrong, M. S. Donnenberg and E. J. Sundberg, "Structure of Clostridium difficile PilJ Exhibits Unprecedented Divergence from Known Type IV Pilins", J. Biol. Chem. 289, 4334 (2014), doi: 10.1074/jbc.M113.534404

W. Wan and G. Stubbs, "Fiber Diffraction of the Prion-Forming Domain HET-s(218-289) Shows Dehydration-Induced Deformation of a Complex Amyloid Structure", Biochemistry 53, 2366 (2014), doi: 10.1021/bi5002807

W. Wan and G. Stubbs, "Fungal Prion HET-s as a Model for Structural Complexity and Self-propagation in Prions", Proc. Natl. Acad. Sci. USA 111, 5201 (2014), doi: 10.1073/pnas.1322933111

A. L. Rodarte, Z. S. Nuno, B. H. Cao, R. J. Pandolfi, M. T. Quint, S. Ghosh, J. E. Hein and L. S. Hirst, "Tuning Quantum-Dot Organization in Liquid Crystals for Robust Photonic Applications", ChemPhysChem 15, 1413 (2014), doi: 10.1002/cphc.201301007

A. H. Phillips, A. J. Schoeffler, T. Matsui, T. M. Weiss, J. W. Blankenship, K. Zobel, A. M. Giannetti, E. C. Dueber and W. J. Fairbrother, "Internal Motions Prime ClAP1 for Rapid Activation", Nat. Struct. Mol. Biol. 21, 1068 (2014), doi: 10.1038/nsmb.2916

M. O. Sheikh, C. M. Schafer, J. T. Powell, K. K. Rodgers, B. H. M. Mooers and C. M. West, "Glycosylation of Skp1 Affects Its Conformation and Promotes Binding to a Model F-Box Protein", Biochemistry 53, 1657 (2014), doi: 10.1021/bi401707y

C. A. Smith, M. Toth, T. M. Weiss, H. Frase and S. B. Vakulenko, "Structure of the Bifunctional Aminoglycoside-resistance Enzyme AAC(6')-Ie-APH(2'')-Ia Revealed by Crystallographic and Small-angle X-ray Scattering Analysis", Acta Crystallogr. D 70, 2754 (2014), doi: 10.1107/S1399004714017635

A. L. Edwards, T. Matsui, T. M. Weiss and C. Khosla, "Architectures of Whole-Module and Bimodular Proteins from the 6-Deoxyerythronolide B Synthase", J. Mol. Biol. 426, 2229 (2014), doi: 10.1016/j.jmb.2014.03.015

A. F. Taylor, S. K. Amundsen, M. Guttman, K. K. Lee, J. Luo, J. Ranish and G. R. Smith, "Control of RecBCD Enzyme Activity by DNA Binding- and Chi Hotspot-dependent Conformational Changes", J. Mol. Biol. 426, 3479 (2014), doi: 10.1016/j.jmb.2014.07.017

M. D.-L. Suits, B. Pluvinage, A. Law, Y. Liu, A. S. Palma, W. Chai, T. Feizi and A. B. Boraston, "Conformational Analysis of the Streptococcus pneumoniae Hyaluronate Lyase and Characterization of Its Hyaluronan-specific Carboyhydrate-binding Module", J. Biol. Chem. 289, 27264 (2014), doi: 10.1074/jbc.M114.578435

S. J. Kim, J. Fernandez-Martinez, P. Sampathkumar, A. Martel, T. Matsui, H. Tsuruta, T. Weiss, A. Markina-Inarrairaegui, J. B. Bonanno, J. M. Sauder, S. K. Burley, S. C. Almo, M. Rout and A. Sali, "Integrative Structure-Function Mapping of the Nucleoporin Nup133 Suggests a Conserved Mechanism for Membrane Anchoring of the Nuclear Pore Complex", Mol. Cell. Proteomics 13, 2911 (2014), doi: 10.1074/mcp.M114.040915 mcp.M114.040915

N. W. Schmidt, S. Deshayes, S. Hawker, A. Blacker, A. M. Kasko and G. C.-L. Wong, "Engineering Persister-Specific Antibiotics with Synergistic Antimicrobial Functions", ACS Nano 8, 8786 (2014), doi: 10.1021/nn502201a

K. Schmidt, C. J. Tassone, J. R. Niskala, A. T. Yiu, O. P. Lee, T. M. Weiss, C. Wang and J. M.-J. Frechet, "A Mechanistic Understanding of Processing Additive-induced Efficiency Enhancement in Bulk Heterojunction Organic Solar Cells", Adv. Mater. 26, 300 (2014), doi: 10.1002/adma.201303622

M. A. Ojeda-Lopez, D. J. Needleman, C. Song, A. Ginsburg, P. A. Kohl, H. P. Miller, L. Wilson, U. Raviv, M. C. Choi and C. R. Safinya, "Transformation of Taxol-stabilized Microtubules into Inverted Tubulin Tubules Triggered by a Tubulin Conformation Switch", Nat. Mater. 13, 195 (2014), doi: 10.1038/nmat3858

A. L. Rodarte, "Dispersions of Semiconductor Nanoparticles in Thermotropic Liquid Crystal: From Optical Modification to Assisted Self-Assembly", University of California (Merced), 2014; Advisors: S. Ghosh and L. S. Hirst

O. Zribi, "Biocompatible Nanoparticles and Biopolyelectrolytes", University of Colorado, 2014; Advisors: A. Glushchenko and Y. Garbovskiy

J. A. Sellberg, "X-ray Scattering and Spectroscopy of Supercooled Water and Ice", Stockholm University, 2014; Advisor: A. Nilsson

W. Wan, "Structure and Assembly of the Fungal Prion-forming Domain HET-s(218-289)", Vanderbilt University, 2014; Advisor: G. Stubbs

R. C. Huber, "Self-Assembly of Semiconducting Polymers and Fullerenes for Photovoltaic Applications", University of California Los Angeles, 2014; Advisor: S. H. Tolbert

C. Chen, "Soft X-ray Spectroscopy and X-ray Scattering of Ice and Water in Aqueous Solutions", Stanford University, 2014; Advisors: A. Nilsson, L. Cegelski and R. Pecora

D. J. Saltzberg, "Substrate Specificity and Conformational Activation Mechanism of beta-Phosphoglucomutase", Boston University, 2014; Advisors: K. Allen, D. Atkinson and J. Straub

R. J. Pandolfi, "Self-assembly and Design of Tunable Soft Materials", University of California (Merced), 2014; Advisor: L. S. Hirst


K. N. Colbert, D. A. Hattendorf, T. M. Weiss, P. Burkhardt, D. Fasshauer and W. I. Weis, "Syntaxin 1a Variants Lacking an N-peptide or Bearing the LE Mutation Bind to Munc18a in a Closed Conformation", Proc. Natl. Acad. Sci. USA 110, 12637 (2013)

T. M. Davenport, M. Guttman, W. Guo, B. Cleveland, M. Kahn, S.-L. Hu and K. K. Lee, "Isolate-Specific Differences in the Conformational Dynamics and Antigenicity of HIV-1 gp120", J. Virol. 87, 10855 (2013)

J. Deek, P. J. Chung, J. Kayser, A. R. Bausch and C. R. Safinya, "Neurofilament Sidearms Modulate Parallel and Crossed-filament Orientations Inducing Nematic to Isotropic and Re-entrant Birefringent Hydrogels", Nat. Commun. 4, 2224 (2013)

B. G. Fritz, S. A. Roberts, A. Ahmed, L. Breci, W. Li, A. Weichsel, J. L. Brailey, V. H. Wysocki, F. Tama and W. R. Montfort, "Molecular Model of a Soluble Guanylyl Cyclase Fragment Determined by Small-Angle X-ray Scattering and Chemical Cross-Linking", Biochemistry 52, 1568 (2013)

M. Guttman and K. K. Lee, "A Functional gp41-gp120 Interaction is Observed in Monomeric but not Oligomeric, Uncleaved HIV-1 Env gp140", J. Virol. (2013)

M. Guttman, P. Weinkam, A. Sali and K. K. Lee, "All-Atom Ensemble Modeling to Analyze Small-Angle X-ray Scattering of Glycosylated Proteins", Structure 21, 321 (2013)

S. D. Hansen, A. V. Kwiatkowski, C.-Y. Ouyang, H. Liu, S. Pokutta, S. C. Watkins, N. Volkmann, D. Hanein, W. I. Weis, R. D. Mullins and W. J. Nelson, "Alpha-E-Catenin Actin Binding Domain Alters Actin Filament Conformation and Regulates Binding of Nucleation and Disassembly Factors", Mol. Biol. Cell 24, 3719 (2013)

M.-C. Ho, C. Wilczek, J. B. Bonanno, L. Xing, J. Seznec, T. Matsui, L. G. Carter, T. Onikubo, T. R. Kumar, M. K. Chan, M. Brenowitz, R. H. Cheng, U. Reimer and D. Shechter, "Structure of the Arginine Methyltransferase PRMT5-MEP50 Reveals a Mechanism for Substrate Specificity", PLoS One 8, e57008 (2013)

K. Hu, N. W. Schmidt, R. Zhu, Y. Jiang, G. H. Lai, G. Wei, E. F. Palermo, K. Kuroda, G. C. L. Wong and L. Yang, "A Critical Evaluation of Random Copolymer Mimesis of Homogeneous Antimicrobial Peptides", Macromolecules 46, 1908 (2013)

J. L. Jenkins, A. A. Agrawal, A. Gupta, M. R. Green and C. L. Kielkopf, "U2AF65 Adapts to Diverse Pre-mRNA Splice Sites through Conformational Selection of Specific and Promiscuous RNA Recognition Motifs", Nucleic Acids Res. 41, 3859 (2013)

J.-P. Julien, J. H. Lee, A. Cupo, C. D. Murin, R. Derking, S. Hoffenberg, M. J. Caulfield, C. R. King, A. J. Marozsan, P. J. Klasse, R. W. Sanders, J. P. Moore, I. A. Wilson and A. B. Ward, "Asymmetric Recognition of the HIV-1 Trimer by Broadly Neutralizing Antibody PG9", Proc. Natl. Acad. Sci. USA 110, 4351 (2013)

A. Kendall, W. Bian, A. Maris, C. Azzo, J. Groom, D. Williams, J. Shi, P. L. Stewart, J. S. Wall and G. Stubbs, "A Common Structure for the Potexviruses", Virology 436, 173 (2013)

A. Kendall, D. Williams, W. Bian, P. L. Stewart and G. Stubbs, "Barley Stripe Mosaic Virus: Structure and Relationship to the Tobamoviruses", Virology 443, 265 (2013)

C. Leal, K. K. Ewert, N. F. Bouxsein, R. S. Shirazi, Y. Li and C. R. Safinya, "Stacking of Short DNA Induces the Gyroid Cubic-to-Inverterd Hexagonal Phase Transition in Lipid-DNA Complexes", Soft Matter 9, 795 (2013)

Y. Matsumura, M. Shinjo, T. Matsui, K. Ichimura, J. Song and H. Kihara, "Structural Study of hNck2 SH3 Domain Protein in Solution by Circular Dichroism and X-ray Solution Scattering", Biophys. Chem. 175, 39 (2013)

P. W. Miller, S. Pokutta, A. Ghosh, S. C. Almo, W. I. Weis, W. J. Nelson and A. V. Kwiatkowski, "Danio rerio aE-catenin is a Monomeric F-actin Binding Protein With Distinct Properties from Mus musculus aE-catenin ", J. Biol. Chem. 288, 22324 (2013)

D. J. Needleman, M. A. Ojeda-Lopez, U. Raviv, H. P. Miller, Y. Li, C. Song, S. C. Feinstein, L. Wilson, M. C. Choi and C. R. Safinya, "Ion Specific Effects in Bundling and Depolymerization of Taxol-stabilized Microtubules", Faraday Discuss. 166, 31 (2013)

B. Pluvinage, S. Chitayat, E. Ficko-Blean, W. Abbott, J. M. Kunjachen, J. Grondin, H. L. Spencer, S. P. Smith and A. B. Boraston, "Conformational Analysis of StrH, the Surface-Attached exo-ß-D-N-Acetylglucosaminidase from Streptococcus pneumoniae", J. Mol. Biol. 425, 334 (2013)

P. Sampathkumar, S. J. Kim, P. Upla, W. J. Rice, J. Phillips, B. L. Timney, U. Pieper, J. B. Bonanno, J. Fernandez-Martinez, Z. Hakhverdyan, N. E. Ketaren, T. Matsui, T. M. Weiss, D. L. Stokes, J. M. Sauder, S. K. Burley, A. Sali, M. P. Rout and S. C. Almo, "Structure, Dynamics, Evolution, and Function of a Major Scaffold Component in the Nuclear Pore Complex", Structure 21, 560 (2013)

N. W. Schmidt, A. Mishra, J. Wang, W. F. DeGrado and G. C. L. Wong, "Influenza Virus A M2 Protein Generates Negative Gaussian Membrane Curvature Necessary for Budding and Scission", J. Am. Chem. Soc. 135, 137 (2013)

X. Shi, D. Herschlag and P. A. B. Harbury, "Structural Ensemble and Microscopic Elasticity of Freely Diffusing DNA by Direct Measurement of Fluctuations", Proc. Natl. Acad. Sci. USA 110, E1444 (2013)

B. F. B. Silva, R. N. Majzoub, C.-L. Chan, Y. Li, U. Olsson and C. R. Safinya, "PEGylated Cationic Liposome-DNA Complexation in Brine is Pathway-Dependent", Biochim. Biophys. Acta 1838, 398 (2013)

A. L. Stiegler, T. D. Grant, J. R. Luft, D. A. Calderwood, E. H. Snell and T. J. Boggon, "Purification and SAXS Analysis of the Integrin Linked Kinase, PINCH, Parvin (IPP) Heterotrimeric Complex", PLoS One 8, e55591 (2013)

M. S. Strycharska, E. Arias-Palomo, A. Y. Lyubimov, J. P. Erzberger, V. L. O'Shea, C. J. Bustamante and J. M. Berger, "Nucleotide and Partner-Protein Control of Bacterial Replicative Helicase Structure and Function", Mol. Cell 52, 844 (2013)

W. Wan, W. Bian, M. McDonald, A. Kijac, D. E. Wemmer and G. Stubbs, "Heterogeneous Seeding of a Prion Structure by a Generic Amyloid Form of the Fungal Prion-Forming Domain HET-s(218-289)", J. Biol. Chem. 288, 29604 (2013)

Q. Wang, T. Matsui, T. Domitrovic, Y. Zheng, P. C. Doerschuk and J. E. Johnson, "Dynamics in Cryo EM Reconstructions Visualized with Maximum-likelihood Derived Variance Maps", J. Struct. Biol. 181, 195 (2013)

Y. Wu, A. P. West, Jr, H. J. Kim, M. E. Thornton, A. B. Ward and P. J. Bjorkman, "Structural Basis for Enhanced HIV-1 Neutralization by a Dimeric Immunoglobulin G Form of the Glycan-recognizing Antibody 2G12", Cell Rep. 5, 1443 (2013)


E. Boura, B. Rozycki, H. S. Chung, D. Z. Herrick, B. Canagarajah, D. S. Cafiso, W. S. Eaton, G. Hummer and J. H. Hurley, "Solution Structure of the ESCRT-1 and -11 Supercomplex: Implications for Membrane Budding and Scission", Structure 20, 874 (2012)

J. W. Chartron, D. G. VanderVelde, M. Rao and W. M. Clemons, Jr., "Get5 Carboxyl-terminal Domain is a Novel Dimerization Motif that Tethers an Extended Get4/Get5 Complex", J. Biol. Chem. 287, 8310 (2012)

C. N. Cunningham, D. R. Southworth, K. A. Krukenberg and D. A. Agard, "The Conserved Arginine 380 of Hsp90 is not a Catalytic Residue, but Stabilizes the Closed Conformation Required for ATP Hydrolysis", Protein Sci. 21, 1162 (2012)

T. Domitrovic, T. Matsui and J. E. Johnson, "Dissecting Quasi-equivalence in Non-enveloped Viruses: Membrane Disruption is Promoted by Lytic Peptides Released from Subunit Pentamers, not Hexamers", J. Virol. 86, 9976 (2012)

A. Gopal, Z. H. Zhou, C. M. Knobler and W. M. Gelbart, "Visualizing Large RNA Molecules in Solution", RNA 18, 284 (2012)

W. Guo, J. M. West, A. S. Dutton, H. Tsuruta and E. R. Kantrowitz, "Trapping and Structure Determination of an Intermediate in the Allosteric Transition of Aspartate Transcarbamoylase", Proc. Natl. Acad. Sci. USA 109, 7741 (2012)

M. Guttman, M. Kahn, N. K. Garcia, S.-L. Hu and K. K. Lee, "Solution Structure, Conformational Dynamics, and CD4-induced Activation in Full-length, Glycosylated, Monomeric HIV gp120", J. Virol. 86, 8750 (2012)

M. A. Jamros, L. C. Oliveira, P. C. Whitford, J. N. Onuchic, J. A. Adams and P. A. Jennings, "Substrate-Specific Reorganization of the Conformational Ensemble of CSK Implicates Novel Modes of Kinase Function", PLOS Comput. Biol. 8, e1002695 (2012)

T. Keiber, F. Bridges, R. E. Baumbach and M. B. Maple, "Unusual Local Disorder in NdOs4Sb12 and PrOs4Sb12 Skutterudites", Phys. Rev. B 86, 174106 (2012)

P. S. Lee, H.-M. Zhang, A. G. Marshall, X.-L. Yang and P. Schimmel, "Uncovering of a Short Internal Peptide Activates a tRNA Synthetase Procytokine", J. Biol. Chem. 287, 20504 (2012)

A. Martel, P. Liu, T. M. Weiss, M. Niebuhr and H. Tsuruta, "An Integrated High-throughput Data Acquisition System for Biological Solution X-ray Scattering Studies", J. Synchrotron Radiat. 19, 431 (2012)

O. Martinez-Avila, S. Wu, S. J. Kim, Y. Cheng, R. Samudrala, F. Khan, A. Sali, J. A. Horst and S. Habelitz, "Self-assembly of Filamentous Amelogenin Requires Calcium and Phosphate: From Dimers via Nanoribbons to Fibrils", Biomacromolecules 13 , 3494 (2012)

M. McDonald, H. Box, W. Bian, A. Kendall, R. Tycko and G. Stubbs, "Fiber Diffraction Data Indicate a Hollow Core for the Alzheimer's Ab 3-Fold Symmetric Fibril", J. Mol. Biol. 423, 454 (2012)

N. Noinaj, N. C. Easley, M. Oke, N. Mizuno, J. Gumbart, E. Boura, A. N. Steere, O. Zak, P. Aisen, E. Tajkhorshid, R. W. Evans, A. R. Gorringe, A. B. Mason, A. C. Steven and S. K. Buchanan, "Structural Basis for Iron Piracy by Pathogenic Neisseria", Nature 483, 53 (2012)

C. Peters-Libeu, J. Miller, E. Rutenber, Y. Newhouse, P. Krishnan, K. Cheung, D. Hatters, E. Brooks, K. Widjaja, T. Tran, S. Mitra, M. Arrasate, L. A. Mosquera, D. Taylor, K. H. Weisgraber and S. Finkbeiner, "Disease-associated Polyglutamine Stretches in Monomeric Huntingtin Adopt a Compact Structure", J. Mol. Biol. 421, 587 (2012)

P. Sampathkumar, S. J. Kim, D. Manglicmot, K. T. Bain, J. Gilmore, T. Gheyi, J. Phillips, U. Pieper, J. Fernandez-Martinez, J. D. Franke, T. Matsui, H. Tsuruta, S. Atwell, D. A. Thompson, J. S. Emtage, S. R. Wasserman, M. P. Rout, A. Sali, J. M. Sauder, S. C. Almo and S. K. Burley, "Atomic Structure of the Nuclear Pore Complex Targeting Domain of a Nup116 Homologue from the Yeast, Candida glabrata", Proteins 80, 2110 (2012)

N. W. Schmidt, K. P. Tai, K. Kamdar, A. Mishra, G. H. Lai, K. Zhao, A. J. Ouellette and G. C. L. Wong, "Arginine in alpha-Defensins: Differential Effects on Bactericidal Activity Correspond to Geometry of Membrane Curvature Generation and Peptide-Lipid Phase Behavior", J. Biol. Chem. 287, 21866 (2012)

N. W. Schmidt, M. Lis, K. Zhao, G. H. Lai, A. N. Alexandrova, G. N. Tew and G. C. L. Wong, "Molecular Basis for Nanoscopic Membrane Curvature Generation from Quantum Mechanical Models and Synthetic Transporter Sequences", J. Am. Chem. Soc. 134, 19207 (2012)

R. S. Shirazi, K. K. Ewert, B. F. B. Silva, C. Leal, Y. Li and C. R. Safinya, "Structural Evolution of Environmentally Responsive Cationic Liposome-DNA Complexes with a Reducible Lipid Linker", Langmuir 28, 10495 (2012)

W. Wan, H. Wille, J. Stohr, U. Baxa, S. B. Prusiner and G. Stubbs, "Degradation of Fungal Prion HET-s(218-289) Induces Formation of a Generic Amyloid Fold", Biophys. J. 102, 2339 (2012) Q. Wang, T. Matsui, T. Domitrovic, Y. Zheng, P. C. Doerschuk and J. E. Johnson, "Dynamics in Cryo EM Reconstructions Visualized with Maximum-Likelihood Derived Variance Maps", J. Struct. Biol. , (2012)

Y. Wang, T. S. Corbitt, S. D. Jett, Y. Tang, K. S. Schanze, E. Y. Chi and D. G. Whitten, "Direct Visualization of Bactericidal Action of Cationic Conjugated Polyelectrolytes and Oligomers", Langmuir 28, 65 (2012)

A. L. West, S. E. Evans, J. M. Gonzalez, L. G. Carter, H. Tsuruta, E. Pozharski and S. L. J. Michel, "Ni(II) Coordination to Mixed Sites Modulates DNA Binding of HpNikR via a Long-range Effect", Proc. Natl. Acad. Sci. USA 109, 5633 (2012)

K. Zhao, U.-J. Choe, D. T. Kamei and G. C. L. Wong, "Enhanced Activity of Cyclic Transporter Sequences Driven by Phase Behavior of Peptide-Lipid Complexes", Soft Matter 8, 6430 (2012)


V. E. Ahn, M. L.-H. Chu, H.-J. Choi, D. Tran, A. Abo and W. I. Weis, "Structural Basis of Wnt Signaling Inhibition by Dickkopf Binding to LRP5/6", Dev. Cell 21, 862 (2011)

E. Boura, B. Rozycki, D. Z. Herrick, H. S. Chung, J. Vecer, W. A. Eaton, D. S. Cafiso, G. Hummer and J. H. Hurley, "Solution Structure of the ESCRT-I Complex by Small-Angle X-ray Scattering, EPR, and FRET Spectroscopy", Proc. Natl. Acad. Sci. USA 108, 9437 (2011)

N. F. Bouxsein, C. Leal, C. S. McAllister, K. K. Ewert, Y. Li, C. E. Samuel and C. R. Safinya, "Two-Dimensional Packing of Short DNA with Nonpairing Overhangs in Cationic Liposome-DNA Complexes: From Onsager Nematics to Columnar Nematics with Finite-Length Columns", J. Am. Chem. Soc. 133, 7585 (2011)

J. W. Chartron, G. M. Gonzalez and W. M. Clemons, Jr., "A Structural Model of the Sgt2 Protein and Its Interactions with Chaperones and the Get4/Get5 Complex", J. Biol. Chem. 286, 34325 (2011)

B. N. Chaudhuri, S. Gupta, V. S. Urban, M. R. Chance, R. D'Mello, L. Smith, K. Lyons and J. Gee, "A Combined Global and Local Approach to Elucidate Spatial Organization of the Mycobacterial ParB-parS Partition Assembly", Biochemistry 50, 1799 (2011)

B. N. Chaudhuri and R. Dean, "The Evidence of Large-Scale DNA-Induced Compaction in the Mycobacterial Chromosomal ParB", J. Mol. Biol. 413, 901 (2011)

M. L. Dechassa, K. Wyns, M. Li, M. A. Hall, M. D. Wang and K. Luger, "Structure nd Scm3-mediated Assembly of Budding Yeast Centromeric Nucleosomes", Nat. Commun. 2, 313 (2011)

D. J. Dickinson, W. J. Nelson and W. I. Weis, "A Polarized Epithelium Organized by beta-and alpha-Catenin Predates Cadherin and Metazoan Origins", Science 331, 1336 (2011)

E. C. Dueber, A. J. Schoeffler, A. Lingel, J. M. Elliott, A. V. Fedorova, A. M. Giannetti, K. Zobel, B. Mauer, E. Varfolomeev, P. Wu, H. J. A. Wallweber, S. G. Hymowitz, K. Deshayes, D. Vucic and W. J. Fairbrother, "Antagonists Induce a Conformational Change in cIAP1 that Promotes Autobiquitination", Science 334, 376 (2011)

T. D. Grant, J. R. Luft, J. R. Wolfley, H. Tsuruta, A. Martel, G. T. Montelione and E. H. Snell, "Small Angle X-ray Scattering as a Complementary Tool for High-throughput Structural Studies", Biopolymers 95, 517 (2011)

Y. He and P. J. Bjorkman, "Structure of FcRY, an Avian Immunoglobulin Receptor Related to Mammalian Mannose Receptors, and Its Complex with IgY", Proc. Natl. Acad. Sci. USA 108, 12431 (2011)

M. A. Higgins, E. Ficko-Blean, P. J. Meloncelli, T. L. Lowary and A. B. Boraston, "The Overall Architecture and Receptor Binding of Pneumococcal Carboyhydrate-Antigen-hydrolyzing Enzymes", J. Mol. Biol. 411, 1017 (2011)

D. Hua, L. Kuang and H. Liang, "Self-directed Reconstitution of Proteorhodopsin with Amphiphilic Block Copolymers Induces the Formation of Hierarchically Ordered Proteopolymer Membrane Arrays", J. Am. Chem. Soc. 133, 2354 (2011)

R. K. Huang, R. Khayat, K. K. Lee, I. Gertsman, R. L. Duda, R. W. Hendrix and J. E. Johnson, "The Prohead-1 Structure of Bacteriophage HK97: Implications for Scaffold-mediated Control of Particle Assembly and Maturation", J. Mol. Biol. 408, 541 (2011)

J. S. Joseph, W. Liu, J. Kunken, T. M. Weiss, H. Tsuruta and V. Cherezov, "Characterization of Lipid Matrices for Membrane Protein Crystallization by High-throughput Small Angle X-ray Scattering", Methods 55, 342 (2011)

C. Leal, K. K. Ewert, R. S. Shirazi, N. F. Bouxsein and C. R. Safinya, "Nanogyroids Incorporating Multivalent Lipids: Enhanced Membrane Charge Density and Pore Forming Ability for Gene Silencing", Langmuir 27, 7691 (2011)

T. A. Leonard, B. Tozycki, L. F. Saidi, G. Hummer and J. H. Hurley, "Crystal Structure and Allosteric Activation of Protein Kinase C betaII", Cell 144, 55 (2011)

R. W. Loney, W. R. Anyan, S. C. Biswas, S. B. Rananavare and S. B. Hall, "The Accelerated Late Adsorption of Pulmonary Surfactant", Langmuir 47, 4857 (2011)

A. Mishra, K. P. Tai, N. W. Schmidt, A. J. Ouellette and G. C. L. Wong, "Small-Angle X-ray Scattering Studies of Peptide-Lipid Interactions Using the Mouse Paneth Cell alpha-Defensin Cryptdin-4", Methods Enzymol. 492, 127 (2011)

A. Mishra, G. H. Lai, N. W. Schmidt, V. Z. Sun, A. R. Rodriguez, R. Tong, L. Tang, J. Cheng, T. J. Deming, D. T. Kamei and G. C. L. Wong, "Translocation of HIV TAT Peptide and Analogues Induced by Multiplexed Membrane and Cytoskeletal Interactions", Proc. Natl. Acad. Sci. USA 108, 16883 (2011)

J. N. Pruneda, K. E. Stoll, L. J. Bolton, P. S. Brzovic and R. E. Klevit, "Ubiquitin in Motion: Structural Studies of the Ubiquitin-conjugating Enzyme~Ubiquitin Conjugate", Biochemistry 50, 1624 (2011)

F. Rascon, R. Berthoud, R. Wischert, W. Lukens and C. Coperet, "Access to Well-defined Ruthenium Mononuclear Species Grafted via a Si-Ru Bond on Silane Functionalized Silica", J. Phys. Chem. C 115, 1150 (2011)

C. R. Safinya, U. Raviv, D. J. Needelman, A. Zidovska, M. C. Choi, M. A. Ojeda-Lopez, K. K. Ewert, Y. Li, H. P. Miller, J. Quispe, B. Carragher, C. S. Potter, M. W. Kim, S. C. Feinstein and L. Wilson, "Nanoscale Assembly in Biological Systems: From Neuronal Cytoskeletal Proteins to Curvature Stabilizing Lipids", Adv. Mater. 23, 2260 (2011)

N. W. Schmidt, A. Mishra, G. H. Lai, M. Davis, L. K. Sanders, D. Tran, A. Garcia, K. P. Tai, P. B. McCray, Jr., A. J. Ouellette, M. E. Selsted and G. C. L. Wong, "Criterion for Amino Acid Composition of Defensins and Antimicrobial Peptides Based on Geometry of Membrane Destabilization", J. Am. Chem. Soc. 133, 6720 (2011)

R. S. Shirazi, K. K. Ewert, C. Leal, R. N. Majzoub, N. F. Bouxsein and C. R. Safinya, "Synthesis and Characterization of Degradable Multivalent Cationic Lipids with Disulfide-bond Spacers for Gene Delivery ", Biochim. Biophys. Acta 1808, 2156 (2011)

A. Vailionis, H. Boschker, W. Siemons, E. P. Houwman, D. H. A. Blank, G. Rijnders and G. Koster, "Misfit Strain Accommodation in Epitaxial ABO3 Perovskites: Lattice Rotations and Lattice Modulations", Phys. Rev. B 83, 064101 (2011)

D. J. Waters, K. Engberg, R. Parke-Houben, C. N. Ta, A. J. Jackson, M. F. Toney and C. W. Frank, "Structure and Mechanism of Strength Enhancement in Interpenetrating Polymer Network Hydrogels", Macromolecules 44, 5776 (2011)


R. Beck, J. Deek, J. B. Jones and C. R. Safinya, "Gel-expanded to Gel-condensed Transition in Neurofilament Networks Revealed by Direct Force Measurements", Nat. Mater. 9, 40 (2010)

M. Chavarha, H. Khoojinian, S. C. Biswas, S. B. Rananavare and S. B. Hall, "Hydrophobic Surfactant Proteins Induce a Phosphatidylethanolamine to Form Cubic Phases", Biophys. J. 98, 1549 (2010)

K. K. Ewert, A. Zidovska, A. Ahmad, N. F. Bouxsein, H. M. Evans, C. S. McAllister, C. E. Samuel and C. R. Safinya, "Cationic Lipid-Nucleic Acid Complexes for Gene Delivery and Silencing: Pathways and Mechanisms for Plasmid DNA and siRNA", in W. Bielke and C. Erbacher (eds.)., Topics in Current Chemistry - Nucleic Acid Transfection, Springer, , Heidelberg & New York, (2010), pp. 1-36

R. D. Fisher, M. Ultsch, A. Lingel, G. Schaefer, L. Shao, S. Birtalan, S. S. Sidhu and C. Eigenbrot, "Structure of the Complex Between HER2 and an Antibody Paratope Formed by Side Chains from Tryptophan and Serine", J. Mol. Biol. 402, 217 (2010)

C. Huang, T. M. Weiss, D. Nordlund, K. T. Wikfeldt, L. G. M. Pettersson and A. Nilsson, "Increasing Correlation Length in Bulk Supercooled H2O, D2O and NaCl Solution Determined from Small Angle X-ray Scattering", J. Chem. Phys. 133, 134504 (2010)

M. A. Jamros, L. C. Oliveira, P. C. Whitford, J. N. Onuchic, J. A. Adams, D. K. Blumenthal and P. A. Jennings, "Proteins at Work: A Combined Small Angle X-ray Scattering and Theoretical Determination of the Multiple Structures Involved on the Protein Kinase Functional Landscape", J. Biol. Chem. 285, 36121 (2010)

J. E. Johnson, "Virus Particle Maturation: Insights into Elegantly Programmed Nanomachines", Curr. Opin. Struct. Biol. 20, 210 (2010)

Y.-S. Jun, B. Lee and G. A. Waychunas, "In Situ Observations of Nanoparticle Early Development Kinetics at Mineral-Water Interfaces", Environ. Sci. Technol. 44, 8182 (2010)

J. A. Kenniston and M. A. Lemmon, "Dynamin GTPase Regulation is Altered by PH Domain Mutations Found in Centronuclear Myopathy Patients", EMBO J. 29, 3054 (2010)

A. V. Kwiatkowski, S. L. Maiden, S. Pokutta, H.-J. Choi, J. M. Benjamin, A. M. Lynch, W. J Nelson, W. I. Weis and J. Hardin, "In Vitro and In Vivo Reconstitution if the Cadherin-Catenin-Actin Complex from Caenorhabditis elegans", Proc. Natl. Acad. Sci. USA 107, 14591 (2010)

C. Leal, N. F. Bouxsein, K. K. Ewert and C. R. Safinya, "Highly Efficient Gene Silencing Activity of siRNA Embedded in a Nanostructured Gyroid Cubic Lipid Matrix", J. Am. Chem. Soc. 132, 16841 (2010)

T. Matsui, H. Tsuruta and J. E. Johnson, "Balanced Electrostatic and Structural Forces Guide the Large Conformational Change Associated with Maturation of T = 4 Virus", Biophys. J. 98, 1337 (2010)

M. McDonald, A. Kendall, W. Bian, I. McCullough, E. Lio, W. M. Havens, S. A. Ghabrial and G. Stubbs, "Architecture of the Potyviruses", Virology 405, 309 (2010)

T. Neumann, S. Gajria, N. F. Bouxsein, L. Jaeger and M. Tirrell, "Structural Responses of DNA-DDAB Films to Varying Hydration and Temperature", J. Am. Chem. Soc. 132, 7025 (2010)

P. Sampathkumar, S. A. Ozyurt, J. Do, K. T. Bain, M. Dickey, L. A. Rodgers, T. Gheyi, A. Sali, S. J. Kim, J. Phillips, U. Pieper, J. Fernandez-Martinez, J. D. Franke, A. Martel, H. Tsuruta, S. Atwell, D. A. Thompson, J. Spencer. Emtage, S. R. Wasserman, M. P. Rout, J. Michael. Sauder and S. K. Burley, "Structures of the Autoproteolytic Domain from the Saccharomyces cerevisiae Nuclear Pore Complex Component, Nup145", Proteins: Struct. Funct. Genet. 78, 1992 (2010)

P. Strasser, S. Koh, T. Anniyev, J. Greeley, K. More, C. Yu, Z. Liu, S. Kaya, D. Nordlund, H. Ogasawara, M. F. Toney and A. Nilsson, "Lattice-strain Control of the Activity in Dealloyed Core-shell Fuel Cell Catalysts", Nat. Chem. 2, 454 (2010)

D. J. Waters, K. Engberg, R. Parke-Houben, L. Hartmann, C. N. Ta, M. F. Toney and C. W. Frank, "Morphology of Photopolymerized End-linked Poly(ethylene glycol) Hydrogels by Small-Angle X-ray Scattering ", Macromolecules 43, 6861 (2010)

W. Zhou, C. Long, S. H. Reaney, D. A. Di Monte, A. L. Fink and V. N. Uversky, "Methionine Oxidation Stabilizes Non-toxic Oligomers of alpha-synuclein through Strengthening the Auto-inhibitory Intra-molecular Long-range Interactions", Biochim. Biophys. Acta 1802, 322 (2010)

P. Z. Gatzeva-Topalova, L. R. Warner, A. Pardi and M. C. Sousa, "Structure and Flexibility of the Complete Periplasmic Domain of BamA: The Protein Insertion Machine of the Outer Membrane", Structure 18, 1492 (2010)


M. C. Choi, U. Raviv, H. P. Miller, M. R. Gaylord, E. Kris, D. Ventimiglia, D. J. Needleman, M. W. Kim, L. Wilson, S. C. Feinstein and C. R. Safinya, "Human Microtubule-Associated-Protein Tau Regulates the Number of Protofilaments in Microtubules: A Synchrotron X-ray Scattering Study", Biophys. J. 97, 519 (2009)

M.-C. Ho, J.-F. Menetret, H. Tsuruta and K. N. Allen, "The Origin of the Electrostatic Perturbation in Acetoacetate Decarboxylase", Nature 459, 393 (2009)

C. Huang, K. T. Wikfeldt, T. Tokushima, D. Nordlund, Y. Harada, U. Bergmann, M. Niebuhr, T. M. Weiss, Y. Horikawa, M. Leetmaa, M. P. Ljungberg, O. Takahashi, A. Lenz, L. Ojamae, A. P. Lyubartsev, S. Shin, L. G. M. Pettersson and A. Nilsson, "The Inhomogeneous Structure of Water at Ambient Conditions", Proc. Natl. Acad. Sci. USA 106, 15214 (2009)

K. A. Krukenberg, D. R. Southworth, T. O. Street and D. A. Agard, "pH-dependent Conformational Changes in Bacterial Hsp90 Reveal a Grp94-like Conformation at pH 6 that is Highly Active in Suppression of Citrate Synthase Aggregation ", J. Mol. Biol. 390, 278 (2009)

T. E. Lee, A. R. Chuang, M. S. Marek, S. Doniach and R. H. Fairclough, "Redistribution of Terbium Ions Across Acetylcholine Receptor-enriched Membranes Induced by Agonist Desensitization", Biophys. J. 96, 2637 (2009)

M. M. Lee, C. E. Isaza, J. D. White, R. P.-Y. Chen, G. F.-C. Liang, H. T.-F. He, S. I. Chan and M. K. Chan, "Insight into the Substrate Length Restriction of M32 Carboxypeptidases: Characterization of Two Distinct Subfamilies", Proteins 77, 647 (2009)

A. Lingel, T. M. Weiss, M. Niebuhr, B. Pan, B. A. Appleton, C. Wiesmann, J. Fernando Bazan and W. J. Fairbrother, "Structure of IL-33 and Its Interaction with the ST2 and IL-1RAcP Receptors-Insight into Heterotrimeric IL-1 Signalling Complexes", Structure 17, 1398 (2009)

J. M. Lozano, D. L. Clark, S. D. Conradson, C. Den Auwer, C. Fillaux, D. Guilaumont, D. W. Keogh, J. Mustre de Leon, P. D. Palmer and E. Simoni, "Influence of the Local Atomic Structure in the X-ray Absorption Near Edge Spectroscopy of Neptunium Oxo Ions", Phys. Chem. Chem. Phys. 11, 10396 (2009)

M. M. Murr, G. S. Thakur, Y. Li, H. Tsuruta, I. Mezic and D. E. Morse, "New Pathway for Self-assembly and Emergent Properties", Nano Today 4, 116 (2009)

K. R. Purdy Drew, L. K. Sanders, Z. W. Culumber, O. Zribi and G. C. L. Wong, "Cationic Amphiphiles Increase Activity of Aminoglycoside Antibiotic Tobramycin in the Presence of Airway Polyelectrolytes", J. Am. Chem. Soc. 131, 486 (2009)

H. Shin, K. R. Purdy Drew, J. R. Bartles, G. C. L. Wong and G. M. Grason, "Cooperativity and Frustration in Protein-mediated Parallel Actin Bundles", Phys. Rev. Lett. 103, 238102 (2009)

A. Som, L. Yang, G. C. L. Wong and G. N. Tew, "Divalent Metal Ion Triggered Activity of a Synthetic Antimicrobial in Cardiolipin Membranes", J. Am. Chem. Soc. 131, 15102 (2009)

R. Srivastava, P. Mani and P. Strasser, "In-situ Voltammetric Dealloying of Fuel Cell Catalyst Electrode Layer: A Combined SEM/EPMA Study", J. Power Sources 190, 40 (2009)

H. Wille, W. Bian, M. McDonald, A. Kendall, D. W. Colby, L. Bloch, J. Ollesch, A. L. Borovinskiy, F. E. Cohen, S. B. Prusiner and G. Stubbs, "Natural and Synthetic Prion Structure from X-ray Fiber Diffraction", Proc. Natl. Acad. Sci. USA 106, 16990 (2009)

C. Yu, S. Koh, J. E. Leisch, M. F. Toney and P. Strasser, "Size and Composition Distribution Dynamics of Alloy Nanoparticles Electrocatalysts Probed by Anomalous Small Angle X-ray Scattering (ASAXS)", Faraday Discuss. 140, 283 (2009)

A. Zidovska, H. M. Evans, K. K. Ewert, J. Quispe, B. Carragher, C. S. Potter and C. R. Safinya, "Liquid Crystalline Phases of Dendritic Lipid-DNA Self-Assemblies: Lamellar, Hexagonal, and DNA Bundles", J. Phys. Chem. B 113, 3694 (2009)

A. Zidovska, H. M. Evans, A. Ahmad, K. K. Ewert and C. R. Safinya, "The Role of Cholesterol and Structurally Related Molecules in Enhancing Transfection of Cationic Liposome-DNA Complexes", J. Phys. Chem. B 113, 5208 (2009)


M. Balooch, S. Habelitz, J. H. Kinney, S. J. Marshall and G. W. Marshall, "Mechanical Properties of Mineralized Collagen Fibrils as Influenced by Demineralization", J. Struct. Biol. 162, 404 (2008)

J. P. Cardia, J. Eldo, J. Xia, E. M. O'Day, H. Tsuruta, K. R. Gryncel and E. R. Kantrowitz, "Use of L-Asparagine and N-phosphonacetyl-L-asparagine to Investigate the Linkage of Catalysis and Homotropic Cooperativity in E. coli Aspartate Transcarbomoylase", Proteins: Struct. Funct. Genet. 71, 1088 (2008)

C. N. Cunningham, K. A. Krukenberg and D. A. Agard, "Intra- and Inter-monomer Interactions are Required to Synergistically Facilitate ATP Hydrolysis in HSP90 ", J. Biol. Chem. 283, 21170 (2008)

P. F. Egea, H. Tsuruta, G. P. de Leon, J. Napetschnig, P. Walter and R. M. Stroud, "Structures of the Signal Recognition Particle Receptor from the Archaeon Pyrococcus furiosus: Implications for the Targeting Step at the Membrane", PLoS One 3, e3619 (2008)

K. K. Ewert, C. E. Samuel and C. R. Safinya, "Lipid-DNA Interactions: Structure-Function Studies of Nanomaterials for Gene Delivery", in R. Dias and B. Lindman (eds.)., Interaction of DNA with Surfactant and Polymers, Blackwell, , Boston, MA, (2008), pp. 377-404

K. K. Ewert, A. Ahmad, N. F. Bouxsein, H. M. Evans and C. R. Safinya, "Non-Viral Gene Delivery with Cationic Liposome-DNA Complexes", in J. Le Doux (ed.)., Gene Therapy Protocols, Humana Press, 3rd Ed., Totowa, NJ, (2008), pp. 159-175

O. Farago, K. Ewert, A. Ahmad, H. M. Evans, N. Gronbech-Jensen and C. R. Safinya, "Transitions between Distinct Compaction Regimes in Complexes of Multivalent Cationic Lipids and DNA", Biophys. J. 95, 836 (2008)

F. Forster, B. Webb, K. A. Krukenberg, H. Tsuruta, D. A. Agard and A. Sali, "Integration of Small Angle X-ray Scattering Data into Structural Modeling of Proteins and Their Assemblies", J. Mol. Biol. 382, 1089 (2008)

L. Gan, S. Chen and G. J. Jensen, "Molecular Organization of Gram-negative Peptidoglycan", Proc. Natl. Acad. Sci. USA 105, 18953 (2008)

N. C. Gilbert, M. Niebuhr, H. Tsuruta, T. Bordelon, O. Ridderbusch, A. Dassey, A. R. Brash, S. G. Bartlett and M. E. Newcomer, "A Covalent Linker Allows for Membrane Targeting of an Oxylipin Biosynthetic Complex", Biochemistry 47, 10665 (2008)

D.-P. Hong, A. L. Fink and V. N. Uversky, "Structural Characteristics of the alpha-Synuclein Oligomers Stabilized by the Flavonoid Baicalein", J. Mol. Biol. 383, 214 (2008)

J. B. Jones and C. R. Safinya, "Interplay between Liquid Crystalline and Isotropic Gels in Self-assembled Neurofilament Networks", Biophys. J. 95, 823 (2008)

K. A. Krukenberg, F. Forster, L. M. Rice, A. Sali and D. A. Agard, "Multiple Conformations of E. coli Hsp90 in Solution: Insights into the Conformational Dynamics of Hsp90", Structure 5, 755 (2008)

G. H. Lai, J. C. Butler, O. V. Zribi, I. I. Smalyukh, T. E. Angelini, K. R. Purdy, R. Golestanian and G. C. L. Wong, "Self-organized Gels in DNA/F-Actin Mixtures without Crosslinkers: Networks of Induced Nematic Domains with Tunable Density", Phys. Rev. Lett. 101, 218303 (2008)

K. K. Lee, L. Gan, H. Tsuruta, C. Moyer, J. F. Conway, R. L. Duda, R. W. Hendrix, A. C. Steven and J. E. Johnson, "Virus Capsid Expansion Driven by the Capture of Mobile Surface Loops", Structure 16, 1491 (2008)

H. Liang, G. Whited, C. Nguyen, A. Okerlund and G. D. Stucky, "Inherently Tunable Electrostatic Assembly of Membrane Proteins", Nano Lett. 8, 333 (2008)

R. S. Mathew-Fenn, R. Das and P. A. B. Harbury, "Measuring the Double Helix", Science 322, 446 (2008)

R. S. Mathew-Fenn, R. Das, J. A. Silverman, P. A. Walker and P. A. B. Harbury, "A Molecular Ruler for Measuring Quantitative Distance Distributions", PLoS One 3, e3229 (2008)

M. McDonald, A. Kendall, M. Tanaka, J. S. Weissman and G. Stubbs, "Enclosed Chambers for Humidity Control and Sample Containment in Fiber Diffraction", J. Appl. Crystallogr. 41, 206 (2008) B. C. Ng, M. Yu, A. Gopal, L. H. Rome, H. G. Monbouquette and S. H. Tolbert, "Encapsulation of Semiconducting Polymers in Vault Protein Cages", Nano Lett. 8, 3503 (2008)

L. M. Rice, E. A. Montabana and D. A. Agard, "The Lattice as Allosteric Effector: Structural Studies of alphabeta- and gamma-Tubulin Clarify the Role of GTP in Microtuble Assembly", Proc. Natl. Acad. Sci. USA 105, 5378 (2008)

K.-H. Tang, M. Niebuhr, A. Aulabaugh and M.-D. Tsai, "Solution Structures of 2:1 and 1:1 DNA Polymerase-DNA Complexes Probed by Ultracentrifugation and Small-angle X-ray Scattering", Nucleic Acids Res. 36, 849 (2008)

K.-H. Tang, M. Niebuhr, C.-S. Tung, H.-c. Chan, C.-C. Chou and M.-D. Tsai, "Mismatched dNTP Incorporation by DNA Polymerase beta does not Proceed via Globally Different Conformational Pathways", Nucleic Acids Res. 36, 2948 (2008)

H. Tsuruta and T. C. Irving, "Experimental Approaches for Solution X-ray Scattering and Fiber Diffraction", Curr. Opin. Struct. Biol. 18, 601 (2008)

R. Tuma, H. Tsuruta, K. H. French and P. Prevelige, "Detection of Intermediates and Kinetic Control during Assembly of Bacteriophage P22 Procapsid", J. Mol. Biol. 381, 1395 (2008)

S. Wang, M. T. Overgaard, Y. Hu and D. B. McKay, "The Bacillus subtilis RNA Helicase YxiN is Distended in Solution", Biophys. J. 94, L01 (2008)

Y. Wang, J. Trewhella and D. P. Goldenberg, "Small-angle X-ray Scattering of Reduced Ribonuclease a: Effects of Solution Conditions and Comparisons with a Computational Model of Unfolded Proteins", J. Mol. Biol. 377, 1576 (2008)

J. M. West, J. Xia, H. Tsuruta, W. Guo, E. M. O'Day and E. R. Kantrowitz, "Time Evolution of the Quaternary Structure of Escherichia coli Aspartate Transcarbamoylase upon Reaction with the Natural Substrates and a Slow Tight Binding Inhibitor", J. Mol. Biol. 384, 206 (2008)

L. Yang, V. D. Gordon, D. R. Trinkle, N. W. Schmidt, M. A. Davis, C. DeVries, A. Som, J. E. Cronan, Jr., G. N. Tew and G. C. L. Wong, "Mechanism of a Prototypical Synthetic Membrane-active Antimicrobial: Efficient Hole-punching via Interaction with Negative Intrinsic Curvature Lipids", Proc. Natl. Acad. Sci. USA 105, 20595 (2008)

M. Yu, B. C. Ng, L. H. Rome, S. H. Tolbert and H. G. Monbouquette, "Reversible pH Lability of Cross-linked Vault Nanocapsules", Nano Lett. 8, 3510 (2008)


N. F. Bouxsein, C. S. McAllister, K. K. Ewert, C. E. Samuel and C. R. Safinya, "Structure and Gene Silencing Activities of Monovalent and Pentavalent Cationic Lipid Vectors Complexed with siRNA", Biochemistry 46, 4785 (2007)

M. C. Corbett, Y. Hu, A. W. Fay, H. Tsuruta, M. W. Ribbe, K. O. Hodgson and B. Hedman, "Conformational Differences between Azotobacter vinelandii Nitrogenase MoFe Proteins as Studied by Small-Angle X-ray Scattering", Biochemistry 46, 8066 (2007)

A. Kendall, M. McDonald and G. Stubbs, "Precise Determination of the Helical Repeat of Tobacco Mosaic Virus", Virology 369, 226 (2007)

M. L. Mendillo, C. D. Putnam and R. D. Kolodner, "Escherichia coli MutS Tetramerization Domain Structure Reveals that Stable Dimers but Not Tetramers are Essential for DNA Mismatch Repair in Vivo", J. Biol. Chem. 282, 16354 (2007)

C. A. Mosley, L. Taupenot, N. Biswas, J. P. Taulane, N. H. Olson, S. M. Vaingankar, G. Wen, N. J. Schork, M. G. Ziegler, S. K. Mahata and D. T. O'Connor, "Biogenesis of the Secretory Granule: Chromogranin A Coiled-Coil Structure Results in Unusual Physical Properties and Suggests a Mechanism for Granule Core Condensation", Biochemistry 46, 10999 (2007)

Z. Qin, D. Hu, S. Han, S. H. Reaney, D. A. Di Monte and A. L. Fink, "Effect of 4-hydroxy-2-nonenal Modification on alpha-synuclein Aggregation", J. Biol. Chem. 282, 5862 (2006)

Z. Qin, D. Hu, M. Zhu and A. L. Fink, "Structural Characterization of the Partially Folded Intermediates of an Immunoglobulin Light Chain Leading to Amyloid Fibrillation and Amorphous Aggregation", Biochemistry 46, 3521 (2007)

U. Raviv, T. Nguyen, R. Ghafouri, D. J. Needleman, Y. Li, H. P. Miller, L. Wilson, R. F. Bruinsma and C. R. Safinya, "Microtubule Protofilament Number is Modulated in a Step-wise Fashion by the Charge of Density of an Enveloping Layer", Biophys. J. 92, 278 (2007)

R. Sarma, D. W. Mulder, E. Brecht, R. K. Szilagyi, L. C. Seefeldt, H. Tsuruta and J. W. Peters, "Probing the MgATP-Bound Conformation of the Nitrogenase Fe Protein by Solution Small-Angle X-ray Scattering", Biochemistry 46, 14058 (2007)

K.-H. Tang, H. Guo, W. Yi, M.-D. Tsai and P. G. Wang, "Investigation of the Conformational States of Wzz and the Wzz O-Antigen Complex under Near-Physiological Conditions", Biochemistry 46, 11744 (2007)

A. E. Whitten, D. A. Jacques, B. Hammouda, T. Hanley, G. F. King, J. M. Guss, J. Trewhella and D. B. Langley, "The Structure of KinA-Sda Complex Suggests an Allosteric Mechanism of Histidine Kinase Inhibition", J. Mol. Biol. 368, 407 (2007)

L. Yang, V. D. Gordon, A. Mishra, A. Som, K. R. Purdy, M. A. Davis, G. N. Tew and G. C. L. Wong, "Synthetic Antimicrobial Oligomers Induce a Composition-dependent Topological Transition in Membranes", J. Am. Chem. Soc. 129, 12141 (2007)

X.-L. Yang, M. Kapoor, F. Otero, B. M. Slike, H. Tsuruta, R. Frausto, A. Bates, K. L. Ewalt, D. A. Cheresh and P. Schimmel, "Gain-of-Function Mutational Activation of Human tRNA Synthetase Procytokine", Chem. Biol. 14, 1323 (2007)


J. Eldo, J. P. Cardia, E. M. O'Day, J. Xia, H. Tsuruta and E. R. Kantrowitz, "N-Phosphonacetyl-L-isoasparagine a Potent and Specific Inhibitor of Escherichia coli Aspartate Transcarbamoylase", J. Med. Chem. 49, 5932 (2006)

K. K. Ewert, H. M. Evans, A. Zidovska, N. F. Bouxsein, A. Ahmad and C. R. Safinya, "A Columnar Phase of Dendritic Lipid-based Cationic Liposome-DNA Complexes for Gene Delivery: Hexagonally Ordered Cylindrical Micelles Embedded in a DNA Honeycomb Lattice", J. Am. Chem. Soc. 128, 3998 (2006)

C. Guaqueta, L. K. Sanders, G. C. L. Wong and E. Luijten, "The Effect of Salt on Self-assembled Actin-Lysozyme Complexes", Biophys. J. 90, 4630 (2006)

A. K. Showalter, B. J. Lamarche, M. Bakhtina, M.-I. Su, K.-H. Tang and M.-D. Tsai, "Mechanistic Comparison of High-Fidelity and Error-Prone DNA Polymerases and Ligases Involved in DNA Repair", Chem. Rev. 106, 340 (2006)

O. V. Zribi, H. Kyung, R. Golestanian, T. B. Liverpool and G. C. L. Wong, "Condensation of DNA-actin Polyelectrolyte Mixtures Driven by Ions of Different Valences", Phys. Rev. E 73, 031911 (2006)


T. E. Angelini, H. Liang, W. Wriggers and G. C. L. Wong, "Direct Observation of Counterion Organization in F-actin Polyelectrolyte Bundles", Eur. Phys. J.E 16, 389 (2005)

Y. Bai, R. Das, I. S. Millett, D. Herschlag and S. Doniach, "Probing Counterion Modulated Repulsion and Attraction between Nucleic Acid Duplexes in Solution", Proc. Natl. Acad. Sci. USA 102, 1035 (2005)

M. R. Brzustowicz and A. T. Brunger, "X-ray Scattering from Unilamellar Lipid Vesicles", J. Appl. Crystallogr. 38, 126 (2005)

J. M. Davies, H. Tsuruta, A. P. May and W. I. Weis, "Conformational Changes of p97 During Nucleotide Hydrolysis Determined by Small-angle X-ray Scattering", Structure 13, 183 (2005)

R. C. Hayward, B. F. Chmelka and E. J. Framer, "Template Cross-linking Effects on Morphologies of Swellable Block Copolymer and Mesostructured Silica Thin Films", Macromolecules 38, 7768 (2005)

M. J. Latimer, K. Ito, S. E. McPhillips and B. Hedman, "Integrated Instrumentation for Combined Polarized Single-crystal XAS and Diffraction Data Acquisition for Biological Applications", J. Synchrotron Radiat. 12, 23 (2005)

K. K. Lee, H. Tsuruta, R. W. Hendrix, R. L. Duda and J. E. Johnson, "Cooperative Reorganization of a 420 Subunit Virus Capsid", J. Mol. Biol. 352, 723 (2005)

H. Liang, D. Harries and G. C. L. Wong, "Polymorphism of DNA-anionic Liposome Complexes Reveals Hierarchy of Ion-mediated Interactions", Proc. Natl. Acad. Sci. USA 102, 11173 (2005)

D. J. Needleman, M. A. Ojeda-Lopez, U. Raviv, K. Ewert, H. P. Miller, L. Wilson and C. Safinya, "Radial Compression of Microtubues and the Mechanism of Action of Taxol and Associated Proteins", Biophys. J. 89, 3410 (2005)

U. Raviv, D. J. Needleman, Y. Li, H. P. Miller, L. Wilson and C. R. Safinya, "Cationic Liposome-microtubule Complexes: Pathways to the Formation of Two-state Lipid-protein Nanotubes with Open or Closed Ends", Proc. Natl. Acad. Sci. USA 102, 11167 (2005)

L. K. Sanders, C. Guaqueta, T. E. Angelini, J.-W. Lee, S. C. Slimmer, E. Luijten and G. C. L. Wong, "Structure and Stability of Self-assembled Actin-Lysozyme Complexes in Salty Water", Phys. Rev. Lett. 95, 108302 (2005)

K. A. Stieglitz, K. J. Dusinberre, J. P. Cardia, H. Tsuruta and E. R. Kantrowitz, "Structure of the E. coli Aspartate Transcarbamoylase Trapped in the Middle of the Catalytic Cycle", J. Mol. Biol. 352, 478 (2005)

K. A. Stieglitz, S. C. Pastra-Landis, J. Xia, H. Tsuruta and E. R. Kantrowitz, "A Single Amino Acid Substitution in the Active Site of Escherichia coli Aspartate Transcarbamoylase Prevents the Allosteric Transition", J. Mol. Biol. 349, 413 (2005)

H. Tsuruta, H. Kihara, T. Sano, Y. Amemiya and P. Vachette, "Influence of Nucleotide Effectors on the Kinetics of the Quaternary Structure Transition of Allosteric Aspartate Transcarbamylase", J. Mol. Biol. 348, 195 (2005)

V. N. Uversky, G. Yamin, L. A. Munishkina, M. A. Karyomov, I. S. Millet, S.  Doniach, Y. L. Lyubchenko and A. L. Fink, "Effects of Nitration on the Structure and Aggregation of a-Synuclein", Mol. Brain Res. 134, 84 (2005)

G. Yamin, L. A. Munishkina, M. A. Karymov, Y. L. Lyubchenko, V. N. Uversky and A. L. Fink, "Forcing Nonamyloidogenic b-synuclein to Fibrillate", Biochemistry 44, 9096 (2005)


A. Ahmad, I. S. Millett, S. Doniach, V. N. Uversky and A. L. Fink, "Stimulation of Insulin Fibrillation by Urea-induced Intermediates", J. Biol. Chem. 279, 14999 (2004)

N. Alam, K. A. Stieglitz, M. D. Caban, S. Gourinath, H. Tsuruta and E. R. Kantrowitz, "240's Loop Interactions Stabilize the T State of Escherichia coli Aspartate Transcarbamoylase", J. Biol. Chem. 279, 23302 (2004)

J. E. Johnson, "Virus Structure Analysis with Synchrotron Radiation: Methods and Results", J. Synchrotron Radiat. 11, 89 (2004)

J. E. Kohn, I. S. Millett, J. Jacob, B. Zagrovic, T. M. Dillon, N. Cingel, R. S. Dothager, S. Seifert, P. Thiyagarajan, T. R. Sosnick, M. Z. Hasan, V. S. Pande, I. Ruczinski, S. Doniach and K. W. Plaxco, "Random-coil Behavior and the Dimensions of Chemically Unfolded Proteins", Proc. Natl. Acad. Sci. USA 101, 12491 (2004)

K. K. Lee, L. Gan, H. Tsuruta, R. W. Hendrix, R. L Duda and J. E. Johnson, "Evidence that a Local Refolding Event Triggers Maturation of HK97 Bacteriophage Capsid", J. Mol. Biol. 340, 419 (2004)

D. J. Needleman, M. A. Ojeda-Lopez, U. Raviv, K. Ewert, J. B. Jones, H. P.  Miller, L. Wilson and C. R. Safinya, "Synchrotron X-ray Diffraction Study of   Microtubules Buckling and Bundling under Osmotic Stress: A Probe of Interprotofilament Interactions", Phys. Rev. Lett. 93, 198104 (2004)  

D. J. Needleman, M. A. Ojeda-Lopez, U. Raviv, H. P. Miller, L. Wilson and C.  R. Safinya, "Higher-order Assembly of Microtubules by Counterions: From   Hexagonal Bundles to Living Necklaces", Proc. Natl. Acad. Sci. USA 101, 16099 (2004)  

A. M. Paredes, D. Ferreira, M. Horton, A. Saad, H. Tsuruta, R. Johnston, W. Klimstra, K. Ryman, R. Hernandez, W. Chiu and D. T. Brown, "Conformational Changes in Sindbis virions Resulting from Exposure to Low pH and Interactions with Cells Suggest that Cell Penetration May Occur at the Cell Surface in the Absence of Membrane Fusion", Virology  324, 373 (2004)

K. Takamoto, Das, Q. He, S. Doniach and D. Brenowitz, "Principles of RNA Compaction: Insights from the Equilibrium Folding Pathway of the P4-P6 RNA Domain in Monovalent Cations", J. Mol. Biol. 343, 1195 (2004)                

J. M. West, H. Tsuruta and E. R. Kantrowitz, "A Fluorescent Probe-Labeled Escherichia coli Aspartate Transcarbamoylase that Monitors the Allosteric Conformational State", J. Biol. Chem. 279, 945 (2004)

J. Johnson, "Virus Assembly and Maturation", in E. Westhoff and N. Hardy (Eds.), Folding and Self Assembly of Macromolecules, World Scientific Publishing Co., Bures-sur-Yvette, France (2004) pp. 349-374


A. Ahmad, I. S. Millett, S. Doniach, V. Uversky and A. L. Fink, "Partially Folded Intermediates in Insulin Fibrillation", Biochemistry 42, 11404 (2003)

T. E. Angelini, H. Liang, W. Wriggers and G. C. L. Wong, "Like-charge Attraction between Polyelectrolytes Induced by Counterion Charge Density Waves", Proc. Natl. Acad. Sci. USA 100, 8634 (2003)

R. Das, T. T. Mills, L. W. Kwok, G. S. Maskel, I. S. Millett, S. Doniach, K. D. Finkelstein, D. Herschlag and L. Pollack, "Counterion Distribution around DNA Probed by Solution X-ray Scattering", Phys. Rev. Lett. 90, 188103 (2003)

R. Das, L. W. Kwok, I. S. Millett, Y. Bai, T. T. Mills, J. Jacob, G. S. Maskel, S. Seifert, S. G. J. Mochrie, P. Thiyagarajan, S. Doniach, L. Pollack and D. Herschlag, "The Fastest Global Events in RNA Folding: Electrostatic Relaxation and Tertiary Collapse of the Tetrahymena Ribozyme", J. Mol. Biol. 332, 311 (2003)

H. M. Evans, A. Ahmad, K. Ewert, T. Pfohl, A. Martin-Herranz, R. F. Bruinsma and C. R. Safinya, "Structural Polymorphism of DNA-dendrimer Complexes", Phys. Rev. Lett. 91, 075501 (2003)

A. M. Joubert, A. S. Byrd and V. J. LiCata, "Global Conformations, Hydrodynamics, and X-ray Scattering Properties of Taq and Escherichia coli DNA Polymerases in Solution", J. Biol. Chem. 278, 25341 (2003)

O. Pelletier, E. Pokidysheva, L. S. Hirst, N. Bouxsein, Y. Li and C. R. Safinya, "Structure of Actin Cross-Linked with a-Actinin: A Network of Bundles", Phys. Rev. Lett. 91, 148102 (2003)

V. N. Uversky, L. N. Garriques, I. S. Millett, S. Frokjaer, J. Brange, S. Doniach and A. L. Fink, "Prediction of the Association State of Insulin Using Spectral Parameters", J. Pharm. Sci. 928, 847 (2003)

G. C. L. Wong, A. Lin, J. X. Tang, Y. Li, P. A. Janmey and C. R. Safinya, "Supramolecular Assembly of Actin Filaments into a Lamellar Phase of Crosslinked Two-dimensional Rafts", Phys. Rev. Lett. 91, 018103 (2003)

Shin, D.S., Pellegrini, L., Daniels, D.S., Yelent, B., Craig, L., Bates, D., Yu, D.S., Shivji M.K., Hitomi, C., Arvai, A.S., Volkmann, N., Tsuruta, H., Blundell, T.L., Venkitaraman, A.R., and Tainer, J.A. "Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2." EMBO J. 22, 4566-4576 (2003)


V. M. Abramov, A. M. Vailiev, V. S. Khlebnikov, R. N. Vasilenko, N. L. Kulikova, I. V. Kosarev, A. T. Ishchenko, J. R. Gillespie, I. S. Millett, A. L. Fink and V. N. Uversky, "Structural and Functional Properties of Yersinia pestis Caf1 Capsular Antigen and Their Possible Role in Fulminant Development of Primary Pneumonic Plague ", J. Proteome Res., ASAP Article (2002)

J. Brink, S. J. Ludtke, C. Yang, Z. Gu, S. J. Wakil and W. Chiu, "Quaternary Structure of Human Fatty Acid Synthase by Electron Cryomicroscopy", Proc. Natl. Acad. Sci. USA, (2002)

W.-Y. Choy, F. A. Mulder, K. A. Crowhurst, D. R. Muhandiram, I. S. Millett, S. Doniach, J. D. Forman-Kay, and L. E. Kay "Distribution of Molecular Size within an Unfolded State Ensemble using Small-angle X-ray Scattering and Pulse Field Gradient NMR Techniques ", J. Mol. Biol. 316, 101 (2002)

I. S. Millett, L. E.Townsley, F. Chiti, S. Doniach and K. W. Plaxco, "Equilibrium Collapse and the Kinetic 'Foldability' of Proteins", Biochemistry 41, 321 (2002)

S. Robic, J. M. Berger and S. Marqusee, "Contributions of Folding Cores to the Thermostabilities of Two Ribonucleases H ", Protein Sci. 11, 381 (2002)

R. Russell, X. Zhuang, H. P. Babcock, I. S. Millett, S. Doniach, S. Chu and D. Herschlag, "Exploring the Folding Landscape of a Structured RNA ", Proc. Natl. Acad. Sci. USA 99, 155 (2002)

R. Russell, I. S. Millett, M. W. Tate, L. W. Kwok, B. Nakatani, S. M. Gruner, S. G. J. Mochrie, V. Pande, S. Doniach, D. Herschlag and L. Pollack, "Rapid Compaction During RNA Folding", Proc. Natl. Acad. Sci. USA 99, 4266 (2002)

P. O. Souillac, V. N. Uversky, I. S. Millett, R. Khurana, S. Doniach and A. L. Fink, "Effect of Association State and Conformational Stability on the Kinetics of Immunoglobulin Light Chain Amyloid Fibril Formation at Physiological pH", J. Biol. Chem. 277, 12657 (2002)

P. O. Souillac, V. N. Uversky, I. S. Millett, R. Khurana, S. Doniach and A. L. Fink, "Elucidation of the Molecular Mechanism During the Early Events in Immunoglobulin Light Chain Amyloid Fibrillation: Evidence for an Off-pathway Oligomer at Acidic pH", J. Biol. Chem. 277, 12666 (2002)

D. M. Tiede, R. Zhang and S. Seifert, "Protein Conformations Explored by Difference High-Angle Solution X-ray Scattering: Oxidation State and Temperature Dependent Changes in Cytochrome C", Biochemistry ASAP Article (2002)

V. N. Uversky, J. Li, P. Souillac, I. S. Millett, S. Doniach, R. Jakes, M. Goedert and A. L. Fink, "Biophysical Properties of the Synucleins and Their Propensities to Fibrillate. Inhibition of Synuclein Assembly by a- and ?- Synucleins", J. Biol. Chem. 277, 11970 (2002)

V. M. Abramov, A. M. Vasiliev, R. N. Vasilenko, N. L. Kulikova, I. V. Kosarev, V. S. Khlebnikov, A. T. Ishchenko, S. MacIntyre, J. R. Gillespie, R. Khurana, T. Korpela, A. L. Fink and V. N. Uversky, "Structural and Functional Similarity between Yersinia pestis Capsular Protein Caf1 and Human Interleukin-1ß", Biochemistry 40, 6076 (2001)

M. A. Canady, H. Tsuruta and J. E. Johnson "Analysis of Rapid, Large-Scale Protein Quaternary Structural Changes: Time-Resolved X-ray Solution Scattering of Nudaurelia capensis ? Virus (N?V) Maturation", J. Mol. Biol. 311, 803 (2001)

S. Doniach, "Changes in Biomolecular Conformation Seen by Small Angle X-ray Scattering", Chem. Rev. 101, 1763 (2001)

P. Eastman, N. Grønbech-Jensen and S. Doniach, "Simulation of Protein Folding by Reaction Path Annealing", J. Chem. Phys. 114, 3823 (2001)

R. Khurana, J. R. Gillespie, A. Talapatra, L. J. Minert, C. Ionescu-Zanetti, I. Millett and A. L. Fink, "Partially-folded Intermediates as Critical Precursors of Light Chain Amyloid Fibrils and Amorphous Aggregates", Biochemistry 40, 3525 (2001)

J. Li, V. N. Uversky and A. L. Fink, "Effect of Familial Parkinson's Disease Point Mutations A30P and A53T on the Structural Properties, Aggregation, and Fibrillation of Human alpha-Synuclein", Biochemistry 40, 11604 (2001)

C. P. Macol, H. Tsuruta, B. Stec and E. R. Kantrowitz "Direct Structural Evidence for a Concerted Allosteric Transition in Escherichia coli Aspartate Transcarbamoylase" Nat. Struct. Biol. 8, 423 (2001)

L. Nielsen, R. Khurana, A. Coats, S. Frokjaer, J. Brange, S. Vyas, V. N. Uversky and A. L. Fink, "Effect of Environmental Factors on the Kinetics of Insulin Fibril Formation: Elucidation of the Molecular Mechanism", Biochemistry 40, 6036 (2001)

C. Nishimura, V. N. Uversky and A. L. Fink, "The Effect of Salts on the Stability and Folding of Staphylococcal Nuclease", Biochemistry 40, 2113 (2001)

C. D. Putnam, S. B. Clancy, H. Tsuruta, S. Gonzales, J. G. Wetmur and J. A. Tainer, "Structure and Mechanism of the RuvB Holliday Junction Branch Migration Motor", J. Mol. Biol. 311, 297 (2001)

A. Saad, S. J. Ludtke, J. Jakana, F. J. Rixon, H. Tsuruta and W. Chiu, "Fourier Amplitude Decay of Electron Cryomicroscopic Images of Single Particles and Effects on Structure Determination", J. Struct. Biol. 133, 32 (2001)

C. R. Safinya, "Structures of Lipid-DNA Complexes: Supramolecular Assembly and Gene Delivery", Curr. Opin. Struct. Biol. 11, 440 (2001)

J. B. Sakash, M. K. Williams, H. Tsuruta and E. R. Kantrowitz, "Domain Bridging Interactions. A Necessary Contribution to the Function and Structure of Escherichia coli Aspartate Transcarbamoylase", J. Biol. Chem. 276, 26441 (2001)

R. Tuma, H. Tsuruta, J. M. Benevides, P. E. Prevelige, Jr. and G. J. Thomas, Jr., "Characterization of Subunit Structural Changes Accompanying Assembly of the Bacteriophage P22 Procapsid", Biochemistry 40, 665 (2001)

V. N. Uversky, J. Li and A. L. Fink, "Evidence for a Partially-Folded Intermediate in alpha-Synuclein Fibril Formation", J. Biol. Chem. 276, 10737 (2001)

V. N. Uversky, J. Li and A. L. Fink, "Trimethylamine-N-oxide- induced Folding of alpha-Synuclein", FEBS Lett. 509, 31 (2001)

H. Tsuruta and J. E. Johnson, "Small-Angle Scattering", in M. G. Rossmann and E. Arnold, eds., International Tables for Crystallography, Volume F, Macromolecular Crystallography, Kluwer Academic Publishers, Dordrecht, Boston, London (2001) Chapter 19.3


"Solution Structural Studies and Low-resolution Model of the Schizosaccharomyces pombe sap1 Protein.” M. Bada, D. Walther, B. Arcangioli, S. Doniach and M. Delarue, J. Mol. Biol. 300, 563 (2000).

“In Vivo X-ray Diffraction of Indirect Flight Muscle from Drosophila melanogaster.” T. C. Irving and D. W. Maughan, Biophys. J. 78, 2511 (2000).

"DNA Condensation in Two Dimensions." I. Koltover, K. Wagner and C. R. Safinya, Proc. Natl. Acad. Sci. USA 97, 14046 (2000).

"Maturation Dynamics of a Viral Capsid: Visualization of Transitional Intermediate States." R. Lata, J.F. Conway, N. Cheng, R.L. Duda, R.W. Hendrix, W.R. Wikoff, J.E. Johnson, H. Tsuruta, A.C. Steven, Cell 100, 253-263 (2000).

“Small Angle X-ray Scattering Reveals a Compact Intermediate in RNA Folding.” R. Russell, I. S. Millett, S. Doniach and D. Herschlag, Nature Struct. Biol. 7, 367 (2000).

"Three of the six possible intersubunit stabilizing interactions involving Glu-239 are sufficient for restoration of the homotropic and heterotropic properties of Escherichia coli aspartate transcarbamoylase." J.B. Sakash, R.S. Chan, H. Tsuruta, E.R. Kantrowitz, J. Biol. Chem. 275, 752-758 (2000).

“Structure of Complexes of Cationic Lipids and Poly(Glutamic Acid) Polypeptides: A Pinched Lamellar Phase.” G. Subramanian, R. P. Hjelm, T. J. Deming, G. S. Smith, Y. Li and C. R. Safinya, J. Am. Chem. Soc. 122, 26 (2000).

“Small-angle Scattering and Diffraction.” H. Tsuruta, Synch. Rad. News 13, 10 (2000).

“Zn2+-Mediated Structure Formation and Compaction of the “Natively Unfolded” Human Prothymosin.” V. N. Uversky, J. R. Gillespie, I. S. Millett, A. V. Khodyakova, R. N. Vasilenko, A. M. Vasiliev, I. L. Rodionov, G. D. Kozlovskaya, D. A. Dolgikh, A. L. Fink, S. Doniach, E. A. Permyakov and V. Abramov, Biochem. Biophys. Res. Commun. 267, 663 (2000).

"Reconstruction of Low Resolution Three-dimensional Density Maps from One-dimensional Small Angle X-ray Scattering Data for Biomolecules." D. Walther, F. Cohen and S. Doniach, J. Appl. Cryst. 33, 350 (2000).

“Topologically Linked Protein Rings in the Bacteriophage HK97 Capsid.” W. R. Wikoff, L. Liljas, R. L. Duda, H. Tsuruta, R. W. Hendrix and J. E. Johnson, Science 289, 2129 (2000).

“Hierarchical Self-Assembly of F-Actin and Cationic Lipid Complexes: Stacked Three-Layer Tubule Networks.” G. C. L. Wong, J. X. Tang, A. Lin, Y. Li, P. A. Janmey and C. R. Safinya, Science 288, 2035 (2000).


"Chain collapse can occur concomitantly with the rate-limiting step in protein folding."  K.W. Plaxco, I.S. Millett, D.J. Segel, S. Doniach, D. Baker, Nature Structural Bilolog, 6, 554-556 (1999).

"Characterization of transient intermediates in lysozyme folding with time-resolved small-angle X-ray scattering." D. J. Segel, A. Bachmann, J. Hofrichter, K. O. Hodgson, S. Doniach, T. Kiefhaber, J. Mol. Biol., 288, 489-499 (1999).

"Scaling structure factor amplitudes in electron microscopy using x-ray solution scattering." M.F. Schmid, M.B. Sherman, P. Matsudaira, H. Tsuruta, W. Chiu, J. Struc. Biol. 128, 51-57 (1999).

"Solution structures of dimeric kinesin and ncd motors." D. Stone, R.P. Hjelm Jr., R. Mendelson, Biochemistry, 38, 4938-4947 (1999).

"The 80s loop of the catalytic chain of Escherichia coli aspartate transcarbamoylase is critical for catalysis and homotropic cooperativity" C. Macol, M. Dutta, B. Stec, H. Tsuruta, E.R. Kantrowitz, Protein Science 8, 1305-1313 (1999).

"Solution X-ray scattering-based estimation of electron cryomicroscopy imaging parameters for reconstruction of virus particles." P.A. Thuman-Commike, H. Tsuruta, B. Greene, P.E. Previlige Jr., J. King, W. Chiu, Biophys. J. 76, 2249-2261 (1999).

"Association of partially-folded intermediates of staphylococcal nuclease induces structure and stability." V.N. Uversky, A.S. Karnoup R. Khurana, D.J. Segel, S. Doniach, A.L. Fink, Protein Science 8, 161-173 (1999).

"Tetrameric assembly of full sequence P0 myelin glycoprotein by synchrotron x-ray scattering." H. Inouye, H. Tsuruta, J. Sedzik, K. Uyemura, D.A. Kirschner, Biophys. J., 76, 423-437 (1999).


"A wide-bandpass multilayer monochromator for biological small-angle scattering and fiber diffraction studies." H. Tsuruta, S. Brennan, Z.U. Rek, T.C. Irving, W.H. Tompkins, K.O. Hodgson, J. Appl. Cryst. 31, 672-682 (1998).

"Imaging RNA and dynamic protein segments with low-resolution virus crystallography: Experimental design, data processing and implications of electron density maps."  H. Tsuruta, V.S. Reddy, W.R. Wikoff, J.E. Johnson, J.  J. Mol. Biol. 284, 1439-1452 (1998).

"Kinetics of lysozyme refolding: Structural characterization of a non-specifically collapsed state using time-resolved X-ray scattering." L. Chen, G. Wildegger, T. Kiefhaber, K.O. Hodgson, S.J.  Doniach, Mol. Biol. 276, 225-237 (1998).

"Direct Observation of an Altered Quaternary Structure Transition in a Mutant Aspartate Transcarbamoylase." H. Tsuruta, P. Vachette, E.R. Kantrowitz, Proteins Structure, Function, and Genetics 31, 383-390 (1998).

"Protein denaturation: A small-angle X-ray scattering study of the ensemble of unfolded states of cytochrome c." D.J. Segel, A.L Fink, K.O. Hodgson, S. Doniach, Biochemistry 37, 12443-12541 (1998).

"Activity-dependent changes of lattice spacings in frog skeletal muscle" H. Tsuruta, T. C. Irving, S. R. Taylor, J. Gen. Phys. 112, 14A (1998).


"A lysozme folding intermediate revealed by solution x-ray scattering." L. Chen, K.O. Hodgson, S. Doniach, J. Mol. Biol. 261, 658-671 (1996).


"Time-Resolved Small Angle X-ray Scattering Establishes that an Apomyoglobin Kinetic Folding Intermediate is Compact." D. Eliezer, P.E. Wright, S. Doniach, K.O. Hodgson, H. Tsuruta, P.A. Jennings, Science 270, 487-488 (1995).

"Solution Small-angle X-ray Scattering Study of the Molecular Chaperone Hsc70 and its Subfragments." L. Chen, S. Wilbanks, H. Tsuruta, K.O. Hodgson, D.B. McKay Biochemistry 34, 12095-12106 (1995) .


"Kinetics of the quatermary structure change of aspartate transcarbamylase triggered by succinate, a competitive inhibitor." H. Tsuruta, P. Vachette,  T. Sano, M.F. Moody, Y. Amemiya, K. Wakabayashi, H. Kihara, Biochemistry 33, 10007-10012 (1994).


"Evidence of an associative intermediate on the myoglobin refolding pathway." D. Eliezer, K. Chiba, H. Tsuruta, S. Doniach, K.O. Hodgson, H. Kihara, Biophys. J. 65, 912-917 (1993).

"MgATP-Induced Conformational Changes in the Iron Protein from Azotobacter vinelandii, as Studied by Small-Angle X-ray Scattering." L. Chen, N. Gavini, H. Tsuruta, D. Eliezer, B.K. Burgess, S. Doniach, K.O. Hodgson,  J. Biol. Chem. 269, 3290-3294 (1993).