Photon Science Seminar: Dr. Tom Oliver, University of Bristol, "Ultrafast charge transfer in biomolecules, macromolecular receptors, and de novo proteins"

Abstract
I will highlight recent work from my group on photoinduced energy and charge-transfer processes using ultrafast optical spectroscopies.  We explore synthetic carbohydrate-binding proteins (lectins) that exhibit intrinsic  fluorescence modulation in response to binding glucose. Our ultrafast measurements reveal that intramolecular charge-transfer within these lectins governs their  fluorescence behaviour. Glucose binding changes the associated non-radiative rate and thus providing a molecular basis for their sensing mechanism.  The UV photoinduced ionization of aromatic amino acids have been studied. The electron ejection mechanism dictates the radiative decay pathway and controls  triplet-state yields in aqueous environments.  Using ultrafast two-dimensional electronic spectroscopy with sub-8 fs time resolution and >150 nm bandwidth, we probe the photoinduced dynamics of a model de novo heme-binding protein.

Zoom
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