Overview
Macromolecular Crystallography, 16-pole Wiggler End Station
Beam line 9-2 is a wiggler end station dedicated for monochromatic, high-throughput and high-resolution macromolecular crystallography and optimized for SAD and MAD experiments. It can be run in a full remote access mode. It is equipped with a Dectris Pilatus 6M PAD detector and a remote access controlled UV-Vis microspectrophotometer.
See the Macromolecular Crystallography website for details.
Sample Environment —
| Standard | Ambient pressure |
|---|---|
| Sample temperature: 100K - room temperature | |
| Controlled Humidity (Arinax HCI) - upon advanced request |
Instrumentation —
| Detectors | Dectris Pilatus 6M, pixel, sample to detector distance of 165-650 mm, shutterless data collection, fine phi slicing experiments |
|---|---|
| Goniometer | SSRL single-axis microdiffractometer, air bearing, coaxial cold stream, 1.5 micron SOC |
| Cryo Capability | Oxford Cryojet |
| Microspectrophotometer | UV-VIS |
Publications
Publications
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Highlights
Science Highlights
Beam Line 9-2 Science Highlights
First Atomic Structure of an Intact Polyketide Synthase Revealing Two Asynchronous Reaction Chambers
X-ray Crystallography-derived Conformational Ensembles to Better Understand Enzyme Catalysis
The Making of an Enzyme-in-Action Movie
Design of Novel Protein Cages
Structure of the Full-length Clostridium difficile Toxin B
Muscle Disorders at High Resolution: Native American Myopathy and Beyond
Structures of the CRISPR Genome Integration Complex
A New Type of Pilus from the Human Microbiome
A Designed Supramolecular Protein Assembly with in-Vivo Enzymatic Activity
Structure of the DUF2233 Domain in Bacteria and the Stuttering-associated UCE Glycoprotein
Botulinum Neurotoxin is Bio-shielded by NTNHA in a Handshake Complex
Folate Binding Site of Flavin-dependant Thymidylate Synthase and the Mechanistic Implications
Computational Design of Anti-flu Proteins
Structure of the MTIP-MyoA Complex, a Key Component of the Malaria Parasite Invasion Motor
High Resolution Structure of the Neisseria gonorrhoeae Type IV Pilus: A Membrane-bound Fibrous Assembly
Structure of a Putative Metal-Chelate Type ABC Transporter: An Inward-facing Conformation
High Resolution Snapshots for the Complete Reaction Cycle of a Cocaine Catalytic Antibody
Crystal Structure of Iron-dependent Halogenase
Structural Basis of Transciption: Role of the Trigger Loop in Substrate Specificity and Catalysis
Structural Basis for the Promiscuous Biosynthetic Prenylation of Aromatic Natural Products
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