| Recent
Advances in Medical Applications of Synchrotron Radiation Stanford Synchrotron Radiation Laboratory March 4-5, 2002 Program Director: Edward Rubenstein |
 < a href="Rubenstein-Workshop.pdf">PDF of all abstracts |
|
Cancer
of the Lung
Katsuhito Yamasaki, M.D. Department of Radiology, Kobe University Hospital, SPring-8 |
| The
Medical Application
Committee of SPring-8 met. A standard expectation
for diagnosis is differentiation of the tumor as either benign or
malignant, necessitating the risk of biopsy. Our hope is to differentiate
without a biopsy. In our CT 630 biopsy cases, pneumothorax occurred
20% in cytology and 40% in tissue biopsy. Another expectation is early
detection of cancer and angiographies of micro vessels. 1. Refraction imaging and histological correlation is used in excised human lung tissue. Study was performed to evaluate the special resolution with synchrotron radiation on 2mm thick sections of excised normal human lung. Fine structure of secondary pulmonary lobules is visible. Even acinus is visible in excised mouse lung, but human lung is about 20 cm thick. Our target is secondary pulmonary lobule. This is polyhedron; size is from 1 to 1.5 c m. In conventional X-ray study, this is not visible. Lung disease occurred in secondary lobules as schema. Observation of secondary Lobules are important. 2. In another study, we observed refraction lung imaging with analyzer crystal. In this study, the sample is rather thick - about 1 cm. Secondary lobule structure is visible. 3. Earlier detection of lung cancer can be expected. D etectability will improve using Synchrotron radiation. |
