Recent Advances in Medical Applications of Synchrotron Radiation
Stanford Synchrotron Radiation Laboratory
March 4-5, 2002
Program Director: Edward Rubenstein
Keith Hodgson
James Rubenstein
Katsuhito Yamasaki
Helene Elleaume
Giuliana Tromba
Wolf-Rainer Dix
Kazuki Hyodo
Barton Lane
William Thomlinson
Hiroshi Sugiyama
< font face="Verdana, Arial, Helvetica, sans-serif" size="2">Joseph Roberson
Masami Ando
John Kinney
Avraham Dilmanian
Dean Chapman
Zhong Zhong< /font>
Brenda Laster
Roman Tatchyn
Pau l Csonka
Anatomy and Physiology of the Ear: A Potential Site of Medical Application of Synchrotron Radiation

Joseph Roberson, MD

CEO and Medical Director California Ear Institute at Stanford
The human ear utilizes a finely tuned and delicate system of soft tissue and bone to transfer mechanical energy from the air medium of our da ily environment to the fluid filled inner ear. The auditory ossicles are the smallest bones within the human body are a relatively common site of disease and dysfunction. Receptor nerve cells (hair cells) located in the cochlea transform the mechanical energy of the resultant fluid wave into electrical energy. Hair cells transmit their signals to second order neurons located in the central core of the cochlea in the spiral g anglion. Spiral ganglion cell efferent processes make up cochlear (or 8th cranial) nerve that synapse in the brainstem at the cochlear nucleus.

Many of these temporal bone structures have been outside of current clinical imaging techniques due to their size. Hearing loss is a major source of disease and disability among our aging population. The purpose of this presentation is to describe and detail the peripheral auditory system with the aim of aiding interpretation of past studies and potential future medical applications of Synchrotron Radiation.

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