Recent Advances in Medical Applications of Synchrotron Radiation
Stanford Synchrotron Radiation Laboratory
March 4-5, 2002
Program Director: Edward Rubenstein
Keith Hodgson
James Rubenstein
Katsuhito Yamasaki
Helene Elleaume
Giuliana Tromba
Wolf-Rainer Dix
Kazuki Hyodo
Barton Lane
William Thomlinson
Hiroshi Sugiyama
Joseph Roberson
Masami Ando
John Kinney
Avraham Dilmanian
Dean Chapman
Zhong Zhong
Brenda Laster
Roman Tatchyn
Paul Csonka
Diffraction Enhanced Imaging: New Directions and Methods

Dean Chapman

Illinois Institute of Technology
A number of x-ray imaging methods have introduced new contrast mechanisms to radiography in addition to absorption. The Diffraction Enhanced Imaging (DEI) technique has two additional contrast mechanisms, refraction gradie nt and ultra-small-angle scatter rejection (extinction), that have properties that are useful for soft tissue imaging as well as the potential to greatly reduce x-ray exposure. Some recent results of the application and analysis of DEI for breast cancer imaging and cartilage/joint imaging will be presented. Also, new methods of image analysis that extract more information will be presented. These new methods indicate that th e potential exists to reduce the dose while still obtaining useful information. Finally, an update on efforts to assess if DEI can be developed into a viable laboratory / clinical system will be discussed.

This work is supported by the National Institutes of Health grant R21 GM59395-01, the U. S. Army MRMC grant DAMD17-99-9217 (D.C.) and State of Illinois Higher Education Cooperative Agre ement.

Presenter Contact Information:
Prof. Dean Chapman
Biological, Chemical and Physical Sciences
Illinois Institute of Technology
3101 South Dearborn
Chicago, IL 60616

phone: 312-567-3575
FAX: 312-567-3576
E-mail: dean.chapman@iit.edu



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