Staff R&D Publications

  1. Mix-and-inject XFEL crystallography reveals gated conformational dynamics during enzyme catalysis.
  2. Strategies for sample delivery for femtosecond crystallography
  3. The conformational flexibility of the acyltransferase from the disorazole polyketide synthase is revealed by an x-ray free-electron laser using a room-temperature sample delivery method for serial crystallography.
  4. High-density grids for efficient data collection from multiple crystals.
  5. Crystal structure of the pristine peroxidase ferryl center and its relevance to proton-coupled electron transfer.
  6. UV-Visible absorption spectroscopy enhanced x-ray crystallography at synchrotron and x-ray free electron laser sources.
  7. The Stanford Automated Mounter: pushing the limits of sample exchange at the SSRL macromolecular crystallography beamlines.
  8. Measuring and modeling diffuse scattering in protein X-ray crystallography.
  9. Capture and X-ray diffraction studies of protein microcrystals in a microfluidic trap array.
  10. Identifying, studying and making good use of macromolecular crystals.
  11. Goniometer-based femtosecond crystallography with X-ray free electron lasers.
  12. Use of transmission electron microscopy to identify nanocrystals of challenging protein targets.
  13. AutoDrug: fully automated macromolecular crystallography workflows for fragment-based drug discovery.
  14. Crystallographic and single-crystal spectral analysis of the peroxidase ferryl intermediate
  15. Remote access to crystallography beamlines at SSRL: novel tools for training, education and collaboration
  16. Web-Ice: intergrated data collection and analysis for macromolecular crystallography
  17. New paradigm for macromolecular crystallography experiments at SSRL: automated crystal screening and remote data collection.
  18. Diffraction-based automated crystal centering.
  19. The 2.7-A crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase (largest MAD structure to date)
  20. Automated diffraction image analysis and spot searching for high-throughput crystal screening
  21. Beamstop with integrated x-ray sensor
  22. Faster data-collection strategies for structure determination using anomalous dispersion
  23. An automated system to mount cryo-cooled protein crystals on a synchrotron beam line, using compact sample cassettes and a small-scale robot.
  24. Blu-Ice and the Distributed Control System: software for data acquisition and instrument control at macromolecular crystallography beamlines.
  25. MAD phasing with krypton.
  26. Successful flash-cooling of xenon-derivatized myoglobin crystals