Macromolecular Crystallography Beamlines

BL12-1 BL12-2 BL9-2 BL14-1 MFX
Flux (p/s) 1e+13 (0.98 Å) 4e+12 (0.98 Å) 7e+11 (0.98 Å) 2e+11 (1.2 Å) 1e+12 (per pulse)
Experiment Types Monochromatic, Polychromatic, MAD, SAD, Microbeam, Serial Monochromatic, MAD, SAD, Microbeam, Serial Monochromatic, MAD, SAD, Minibeam Monochromatic, MAD, SAD, Minibeam Polychromatic, Femtosecond, Microbeam, Serial
Beam Size (um) * 5 x 50 15 x 50 60 x 60 50 x 50 1 x 1
Collimated Beam Size 1 x 1 10 x 10
Max Image Rate (Hz) * >100 20 20 0.5 33
% General Use 50% 78% 100% 100% 100%

The Macromolecular Crystallography (MC) group supports state-of-the-art X-ray crystallography beamline (BL) facilities that are optimized for monochromatic, single-wavelength (SAD) and multi-wavelength anomalous dispersion (MAD) X-ray diffraction experiments at ambient and cryogenic temperatures. The beamline designs have been optimized to provide macromolecular crystallography facilities with state-of-the-art Parameters and latest cutting-edge Features.

BL12-2 is a undulator beamline optimized for experiments that can make use of an intense microbeam (for example, studies that involve microcrystals).  BL12-1 is a new undulator beamline with an even smaller microbeam capability, currently in the final commissioning phase. The beamlines are outfitted with cutting-edge pixel array X-ray detectors (PADs). High-end data storage and computational systems are available for near real-time data processing.  The beamlines are fully automated and the majority of our current user groups ship frozen samples and collect crystallographic and complementary spectroscopic data from remote locations, across the US and the world. 

The MC group also supports fixed-target femtosecond X-ray diffraction experiments on the MFX station at the LCLS.