Solar panels contain a number of solar cells that convert light into electricity. Solar cells are traditionally made of crystalline silicon, which presently have 15-20% efficiency in conversion of light into electricity. However, these traditional cells are bulky and have high production costs that can take 5-7 years of solar panel operation to recover. Using solar cells made from organic materials could lower their production costs. This would lessen the time it takes for solar panels to generate more energy than consumed during production and would also result in more widespread application of solar energy.
Approximately 1,600 scientists visit SSRL annually to conduct experiments in broad disciplines including life sciences, materials, environmental science, and accelerator physics. Science highlights featured here and in our monthly newsletter, Headlines, increase the visibility of user science as well as the important contribution of SSRL in facilitating basic and applied scientific research. Many of these scientific highlights have been included in reports to funding agencies and have been picked up by other media. Users are strongly encouraged to contact us when exciting results are about to be published. We can work with users and the SLAC Office of Communication to develop the story and to communicate user research findings to a much broader audience. Visit SSRL Publications for a list of the hundreds of SSRL-related scientific papers published annually and to add your most recent publications to this collection.
While we continue to refine our science highlights content you may access older science summaries that date between 04/2001 to 06/2010 by visiting http://www-ssrl.slac.stanford.edu/science/sciencehighlights.html. We will be offering science summaries that date from 06/2012 to the present soon.
The world's animals depend on plants, plants depend on photosynthesis, and photosynthesis depends on iron. Despite a relative abundance of this element, iron in a form useable by plants can be rare. Living organisms require soluble iron, which generally comes from environments in flux since iron settles into stable minerals unavailable to life. Since around 30-40% of oceans are iron-limited, understanding the sources of soluble iron is critical to understanding oceanic ecosystems, which are responsible for taking significant amounts of carbon out of the air.
Diatoms, unicellular algae that exist almost anywhere there is water, have recently attracted attention as potential thwarters of climate change. Diatoms go through cycles of blooms, where they grow and multiply rapidly near the ocean's surface. Scarcity of a nutrient will trigger the end of a bloom and the algae sink, taking with them large amounts of sequestered carbon from the air to the bottom of the ocean. Because iron is a limiting nutrient in about 30-40% of the world's oceans, some researchers propose that artificially enriching iron in oceans would promote diatom growth and carbon dioxide capture similar to the hypothesized scenario that occurs during glacial periods when iron input into the ocean is higher.
The amount of lead particulates in air has decreased significantly as the U.S. began adopting the use of unleaded gasoline and lead limits in the 1970s. Yet, because of the serious health hazards even very small amounts of lead pose to children, some experts believe no amount of lead in our environment is safe. Last year the EPA lowered the allowable lead level in the air by a factor of ten and some have called for an even lower limit. A recent study suggests that to do this one must not overlook the source of lead contamination beneath our feet. The soil serves as a reservoir for lead from the days of leaded gasoline and unregulated manufacturing and may determine a lower limit on the amount of airborne lead.
Metals such as iron, copper, and zinc are critical for brain function, where they serve various roles, such as enzyme cofactors or neurotransmitters. Because the metal atoms can be reactive and cause cell damage, their locations and concentrations are tightly controlled. This control can be lost in some neurodegenerative diseases. Diseases like Alzheimer's dementia and Parkinson's disease are either caused by or lead to increased metal in areas of the brain, while others, like Menkes disease, are characterized by decreased concentrations of metals.
In a similar way to your old pick-up truck rusting in the driveway, your body experiences a continuous battle against the elements. A constant barrage of oxidative stress attacks your cells and their constituent parts, including proteins. Like rust-proof paint on your vehicle, you have defense mechanisms that seek to prevent damage before it starts. But also like your trusty truck, once a weakness in the armor presents itself, it can spread rapidly — and often unnoticed — until you suddenly discover significant damage. Numerous diseases, as well as aging itself, are linked to uncontrolled oxidative processes that lead to irreversible damage and ultimately death. Understanding these oxidative processes may lead toward stopping and possibly even reversing damage.
The tips of crab pincers are made of a very hard material, allowing the crab to fight and forage for food without wearing down their tools. Made mostly of proteins, the tip is known to be bromine-rich instead of calcium-rich, but the biochemical structure and mechanical properties were mostly unknown. Understanding this hard material made by crabs may lead to development of materials made by humans for use in a variety of purposes that require a small, fracture-resistant tool.
Nitric oxide (NO) is one of very few gaseous signaling molecules in humans. NO causes smooth muscles to relax and blood vessels to open. Its deficiency leads to disorders such as hypertension and impotence, but too much NO can lead to rheumatoid arthritis, stroke, cancer, and other diseases. Three distinct but related enzymes (called nitric oxide synthases) make NO from an arginine molecule. One of the nitric oxide synthases, iNOS, creates localized, high concentrations of NO as part of the body's immune response. Because it is this elevated activity of iNOS that can cause disease, scientists would like to specifically inhibit the action of iNOS without interfering with the activity of the other two enzymes, eNOS and nNOS. Since the three enzymes have identical active sites (i.e. where NO is made), finding an inhibitor that will bind in this site for iNOS but not eNOS nor nNOS has proved challenging.
Medications can be rendered ineffective through cells developing multidrug resistance. This is the case in many forms of cancer cells that fail to respond to chemotherapy. The ability of these cells to avoid the effects of drugs can be due to the actions of P-glycoprotein (P-gp). This protein sits in the membranes of cells and acts like a pump. It ushers a wide range of potentially harmful molecules from inside the membrane to outside the cell. Unfortunately, it can also mediate the removal of life-saving medications.
Before DNA is made, the subunits composing DNA must be made. The essential process of making one of these subunits, thymidine monophosphate (TMP), was thought to be similar for most living things, but scientists recently discovered that some bacteria and viruses use a different type of enzyme to perform this reaction. The discovery might result in new antibiotics that would be effective against human pathogens, but not affect human cells.

![Figure 1: Diffraction data for pBTTT:PC[71]BM blends of varying weight ratio that have been annealed at 185 °C for 10 minutes. The annealing took place at the glass transition temperature of pBTTT in order to increase the molecular order. (a) 2D GIXS of pure pBTTT. (b) 2D GIXS of 1:1 pBTTT:PC[71]BM blend. (c) High resolution specular x-ray diffraction for a series of pBTTT:PC[71]BM blends. This confirms the expansion perpendicular to the substrate. Figure 1.](http://www-ssrl.slac.stanford.edu/content/sites/default/files/styles/custom-160/public/images/science/highlights/2009/mayer_fig1.jpg?itok=M_-1qXwB)




![Figure 1. Fundamental biochemical reduction/oxidation processes involving methionine (MetS) sidechains. Structures shown to indicate amino acid within a peptide chain. [O] indicates an oxidative source (e.g. H2O2) and MSR refers to methionine sulfoxide reductase. (Image: Pierre Kennepohl) Figure 1.](http://www-ssrl.slac.stanford.edu/content/sites/default/files/styles/custom-160/public/images/science/highlights/2009/mets_oxidation_fig1.jpg?itok=-wzLD5gc)







